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    Multicomponent crystalline system comprising nilotinib and selected co-crystal formers
    2.
    发明授权
    Multicomponent crystalline system comprising nilotinib and selected co-crystal formers 有权
    包括尼罗替尼和选择的共晶体形成剂的多组分结晶体系

    公开(公告)号：US09567317B2

    公开(公告)日：2017-02-14

    申请号：US14433147

    申请日：2013-10-16

    Applicant: BASF SE

    Inventor： Tiziana Chiodo ,  Andreas Hafner ,  Tobias Hintermann ,  Beate Salvador ,  Martin Szelagiewicz ,  Fritz Blatter ,  Eva Roedel ,  Marcus Vossen

    IPC: C07D401/14

    CPC classification number: C07D401/14

    Abstract: The present invention relates to crystalline materials comprising nilotinib and a carboxylic acid, carboxylic acid ester, carboxylic acid amide or sulfonic acid as a co-crystal former, and to pharmaceutical compositions comprising said materials. The invention also relates to processes for preparing said crystalline materials and to methods of using said crystalline materials to treat a disease condition in which tyrosine kinase inhibition is beneficial.

    Abstract translation: 本发明涉及包含尼罗替尼和羧酸，羧酸酯，羧酸酰胺或磺酸作为共晶体形成剂的结晶材料以及包含所述材料的药物组合物。 本发明还涉及制备所述结晶材料的方法以及使用所述结晶材料治疗其中酪氨酸激酶抑制是有益的疾病状况的方法。

    Salts of Dasatinib in crystalline form
    4.
    发明授权
    Salts of Dasatinib in crystalline form 有权
    达沙替尼盐结晶

    公开(公告)号：US09556164B2

    公开(公告)日：2017-01-31

    申请号：US14907148

    申请日：2014-07-22

    Applicant: BASF SE

    Inventor： Andreas Hafner ,  Fritz Blatter ,  Martin Szelagiewicz ,  Bernd Siebenhaar ,  Tiziana Chiodo ,  Tobias Hintermann ,  Beate Salvador ,  Marcus Vossen

    IPC: C07D417/12 ,  C07D275/06

    CPC classification number: C07D417/12 ,  C07B2200/13 ,  C07D275/06

    Abstract: The present invention primarily relates to molecular crystalline substances, preferably salts of Dasatinib in crystalline form, comprising a compound of formula 1, preferably a cation of a compound of formula 1, and a second compound selected from the group consisting of glutaric acid, nicotinic acid and saccharin, preferably an anion thereof. The invention is further related to pharmaceutical compositions comprising such a substance. Furthermore, the invention relates to processes for preparing said substances. The invention also relates to several aspects of using said substances or pharmaceutical compositions to treat a disease.

    Abstract translation: 本发明主要涉及分子结晶物质，优选结晶形式的达沙替尼盐，其包含式1化合物，优选式1化合物的阳离子和选自戊二酸，烟酸 和糖精，优选其阴离子。 本发明还涉及包含这种物质的药物组合物。 此外，本发明涉及制备所述物质的方法。 本发明还涉及使用所述物质或药物组合物治疗疾病的若干方面。

    PROCESS FOR PREPARING GRAPHENE NANORIBBONS
    6.
    发明申请
    PROCESS FOR PREPARING GRAPHENE NANORIBBONS 有权
    制备石墨纳米粒的方法

    公开(公告)号：US20150225244A1

    公开(公告)日：2015-08-13

    申请号：US14428488

    申请日：2013-09-04

    Applicant: BASF SE ,  EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT

    Inventor： Tobias Hintermann ,  Roman Fasel ,  Pascal Ruffieux ,  Jinming Cai ,  Juan Sanchez Valencia

    IPC: C01B31/04

    CPC classification number: C01B31/0446 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/184 ,  C01B2204/06

    Abstract: The present invention relates to a process for preparing a graphene nanoribbon, which comprises: (a) providing at least one aromatic monomer compound which is selected from at least one polycyclic aromatic monomer compound, at least one oligo phenylene aromatic monomer compound, or combinations thereof, on a solid substrate, (b) polymerization of the aromatic monomer compound so as to form at least one polymer on the surface of the solid substrate, (c) at least partially cyclodehydrogenating the one or more polymers of step (b), wherein at least step (b) is carried out at a total pressure p(total) of at least 1×10−9 mbar; and a partial oxygen pressure p(O2) and partial water pressure p(H2O) which satisfy the following relation: p(O2)×p(H20)

    Abstract translation: 本发明涉及一种制备石墨烯纳米棒的方法，其包括：（a）提供至少一种选自至少一种多环芳族单体化合物，至少一种低聚亚苯基芳族单体化合物或其组合的芳族单体化合物 （b）芳族单体化合物的聚合以在固体基质的表面上形成至少一种聚合物，（c）至少部分地将步骤（b）的一种或多种聚合物环化脱氢，其中 至少步骤（b）以至少1×10 -9毫巴的总压力p（总计）进行; 和满足以下关系的部分氧气压力p（O2）和部分水压p（H2O）：p（O2）×p（H20）<3×10-14 mbar2。

    Daylighting illumination system
    7.
    发明授权
    Daylighting illumination system 有权

    公开(公告)号：US10718479B2

    公开(公告)日：2020-07-21

    申请号：US16346601

    申请日：2017-11-02

    Applicant: BASF SE

    Inventor： Tobias Hintermann ,  Patrice Bujard ,  Andre Kostro ,  Adrian Von Muehlenen ,  Cristobal Garrido Segura

    IPC: F21S11/00 ,  F21V8/00 ,  E04C1/42 ,  E04D13/03 ,  E04C2/54

    Abstract: A daylight illumination system for integration into a building or larger vehicle comprises a translucent facade element (800) containing a glass sheet and a light redirection element (302 or 708), and a light transport channel (801) for guiding light about horizontally into an interior of the building, the light transport channel comprising one opening attached to the interior side of said facade element and at least one opening towards the interior of the building, characterised in that the light redirection element (302 or 708) is formed as a structured polymer film or sheet attached to a glass sheet of the facade element (800) and is configured for changing the direction of incident light into the about horizontal light transport channel.

    PURIFICATION PROCESS FOR GRAPHENE NANORIBBONS
    9.
    发明申请
    PURIFICATION PROCESS FOR GRAPHENE NANORIBBONS 审中-公开
    石墨纳米粒的纯化工艺

    公开(公告)号：US20160207776A1

    公开(公告)日：2016-07-21

    申请号：US14914558

    申请日：2014-08-25

    Applicant: BASF SE

    Inventor： Tobias Hintermann ,  Matthias Georg Schwab ,  Kitty Chih-Pei Cha ,  Thomas Weitz ,  Ansgar Schäfer ,  Imke Britta Müller

    IPC: C01B31/04 ,  H01L29/16 ,  H01L29/78 ,  H01L29/06

    CPC classification number: H01L29/78 ,  C01B32/196 ,  C01B2204/06 ,  H01L29/0669 ,  H01L29/0673 ,  H01L29/1606 ,  H01L29/66037 ,  H01L29/66045 ,  H01L29/7781

    Abstract: In a process for purifying graphene nanoribbons, a composition comprising graphene nanoribbons GNR1 and at least one contaminant is brought into contact with a liquid medium that includes a dispersant. The graphene nanoribbons GNR1 are dispersed in the liquid medium so as to obtain a liquid dispersion of the graphene nanoribbons GNR1. The liquid dispersion of the graphene nanoribbons GNR1 is subjected to a separation treatment so as to at least partly remove the at least one contaminant, thereby obtaining a liquid dispersion of purified graphene nanoribbons GNR1.

    Abstract translation: 在用于纯化石墨烯纳米带的方法中，包含石墨烯纳米带GNR1和至少一种污染物的组合物与包括分散剂的液体介质接触。 将石墨烯纳米带GNR1分散在液体介质中，以获得石墨烯纳米带GNR1的液体分散体。 将石墨烯纳米带GNR1的液体分散体进行分离处理，以至少部分除去至少一种污染物，从而获得纯化的石墨烯纳米带GNR1的液体分散体。

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