Abstract:
Systems and methods for performing tissue modulation are disclosed. A nerve modulation assembly may include a guide sheath having a proximal end, a distal end, and a lumen extending therebetween. An actuation member, also having a proximal end and a distal end, extends along a central elongate axis disposed within the lumen. Further, the ablation member disposed at the distal end of the actuation member is configured to be actuated from the proximal end of the guide sheath. In particular, the ablation member includes a radiofrequency based electrode member, and an insulation member disposed circumferentially around the radiofrequency based electrode member.
Abstract:
Medical devices and methods for making and using the same are disclosed. An example medical device may include an ablative catheter for nerve modulation through a wall of a blood vessel. The catheter may include a catheter sheath having a proximal end, a distal end, and a lumen extending from the proximal to the distal end. An elongate member may extend along a central elongate axis within the lumen of the catheter sheath. The elongate member having a proximal end and a distal end. An expandable ablative member may be coupled to the distal end of the elongate member having an insulative section connected to a bare electrode section. The ablative member may be configured to switch between a collapsed position and an expanded position.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may be a deflectable medical device that includes a catheter shaft having a distal end. An ablation electrode may be disposed at the distal end. A deflection mechanism may be coupled to the catheter shaft. The deflection mechanism may include a deflection body and a pull wire coupled to the deflection body. The deflection body may have a longitudinally-extending furrow formed therein. A flex member may be disposed adjacent to the deflection mechanism.
Abstract:
Medical devices for ablating nerves perivascularly and methods for making and using the same are disclosed. An example medical device may include an expandable frame slidably disposed within a catheter shaft. The expandable frame may be configured to shift between a collapsed configuration and an expanded configuration. One or more electrodes may be disposed on a surface of the expandable frame. The one or more electrodes may be disposed radially inward relative to the greatest radial extent of the expandable frame when the expandable frame is in the expanded configuration.
Abstract:
Systems for nerve and tissue modulation are disclosed. An example system may an elongate shaft including an expandable frame coupled to the shaft adjacent to a distal end of the shaft. The frame may include a plurality of electrically conductive regions for emitting an electrical current comprising at least a first electrically conductive region and a second electrically conductive region. The system may further include a ground pad and a control unit electrically coupled to the plurality of electrically conductive regions and the ground pad. The control and power unit is configured to operate in unipolar mode and bipolar mode during the same procedure.
Abstract:
Systems for nerve and tissue modulation are disclosed. An illustrative system may include an intravascular nerve modulation system including a catheter shaft, an expandable basket and one or more energy delivery regions. The one or more energy delivery regions may be defined by regions of the basket free from an insulating material.
Abstract:
A catheter for ablating target tissue from a location within a body vessel includes an ablation region that is configured to transition from a first substantially straight configuration to a second configuration having a two-dimensional or three-dimensional shape. The ablation region may include a plurality of ablation elements that may be distributed along a length of the ablation region such that when the ablation region is in the second configuration, the ablation elements may be placed in closer proximity to the target tissue. Additionally, when the ablation region is in the second configuration, the ablation elements may achieve circumferential coverage of the body lumen or blood vessel, and as such, may be capable of ablating the target tissue at multiple locations along the length and around a circumference of the body lumen or vessel in a single step.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a system for nerve modulation. The system may include an elongate shaft and a nerve modulation assembly disposed at the distal end of the shaft. The nerve modulation assembly may have a collapsed configuration and an expanded configuration. The nerve modulation assembly may include an inner basket and an outer basket. The inner basket may include a plurality of electrode struts. Each electrode strut may include an electrode. The outer basket may include a plurality of spacer struts.
Abstract:
Medical devices including catheters for renal nerve ablation and/or modulation as well as methods for making and using such devices are disclosed. An example catheter may, have a proximal region and a distal region. The catheter may be configured to shift between a first straightened configuration and a second deflected configuration. The catheter may also include an ablation member coupled to the distal region and a handle coupled to the proximal region. The handle may include an actuation member for shifting the catheter between the first configuration and the second configuration. A lock may be coupled to the handle that maintains the catheter in either the first configuration or the second configuration.