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公开(公告)号：US20150252028A1
公开(公告)日：2015-09-10
申请号：US14434049
申请日：2012-10-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Abstract translation: 本公开涉及用于治疗丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号：US20130034520A1
公开(公告)日：2013-02-07
申请号：US13650374
申请日：2012-10-12
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K31/4178 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D401/14 , A61P31/14 , A61K38/05 , A61K38/21 , A61K31/7056 , A61K38/20 , A61K31/713 , C07D403/14 , A61K31/454
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09776981B2
公开(公告)日：2017-10-03
申请号：US14807084
申请日：2015-07-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D487/04 , C07D309/06 , C07D401/14 , C07D403/14 , C07D471/04 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D403/10 , C07D405/14 , C07D413/14
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20150197499A1
公开(公告)日：2015-07-16
申请号：US14668090
申请日：2015-03-25
Applicant: Bristol-Myers Squibb Company
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D309/06
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US08846023B2
公开(公告)日：2014-09-30
申请号：US14021686
申请日：2013-09-09
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: C07D403/14 , C07D405/14 , C07D417/14 , A61K31/506 , A61K31/4178 , A61K31/427 , A61K31/13 , A61K31/7105 , A61K31/4745 , A61K31/7056 , A61K38/20 , A61K38/21 , C07D401/14
CPC classification number: A61K31/506 , A61K31/13 , A61K31/4178 , A61K31/427 , A61K31/4745 , A61K31/7056 , A61K31/7105 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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Patent Agency Ranking
公开(公告)号：US20180221342A1
公开(公告)日：2018-08-09
申请号：US15749557
申请日：2016-07-27
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David B. Frennesson , Piyasena Hewawasam , Omar D. Lopez , Van N. Nguyen , Mark G. Saulnier , Yong Tu , Alan Xiangdong Wang , Gan Wang , Ningning Xu , Roshan Yadavrao Nimje , Hasibur Rahaman , Samayamunthula Venkata Satya Arun Kumar Gupta , Nicholas A. Meanwell , Makonen Belema
IPC: A61K31/4178 , A61P31/14
CPC classification number: A61K31/4178 , A61K31/417 , A61K31/4184 , A61K31/4439 , A61K31/497 , A61K31/7056 , A61K38/21 , A61K45/06 , A61K2300/00 , A61P31/14
Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
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公开(公告)号：US20170355689A1
公开(公告)日：2017-12-14
申请号：US15689286
申请日：2017-08-29
Applicant: Bristol-Myers Squibb Company
Inventor： RICO LAVOIE , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D309/06 , C07D487/04 , C07D403/10 , A61K31/4184 , A61K31/4375 , A61K31/498 , A61K31/4545 , A61K31/5377 , C07D401/14 , C07D403/14 , C07D405/14 , A61K31/437 , A61K31/4709 , A61K45/06 , C07D413/14 , C07D471/04 , A61K31/4178 , A61K31/4985
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09758487B2
公开(公告)日：2017-09-12
申请号：US15194980
申请日：2016-06-28
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K38/20 , A61K31/4164 , A61K31/517 , A61K31/715 , A61K38/46 , A61P31/00 , C07D403/02 , C07D401/00 , C07D233/64 , C07D401/14 , C07D403/14 , A61K31/4178 , A61K45/06 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20130115193A1
公开(公告)日：2013-05-09
申请号：US13672266
申请日：2012-11-08
Applicant: Bristol-Myers Squibb Company
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D403/14 , A61K31/4545 , C07D401/14 , A61K31/437 , C07D471/04 , A61K31/4985 , C07D487/04 , C07D405/14 , A61K31/498 , A61K31/4178 , A61K31/4375 , A61K31/4709 , A61K31/5377 , C07D413/14 , C07D403/10 , A61K45/06 , A61K31/4184
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09561212B2
公开(公告)日：2017-02-07
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178 , C07D403/14
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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