METHODS OF DIAGNOSING AND TREATING MICROBIOME-ASSOCIATED DISEASE USING INTERACTION NETWORK PARAMETERS
    2.
    发明申请
    METHODS OF DIAGNOSING AND TREATING MICROBIOME-ASSOCIATED DISEASE USING INTERACTION NETWORK PARAMETERS 审中-公开
    使用互动网络参数诊断和治疗微生物相关疾病的方法

    公开(公告)号:US20120149584A1

    公开(公告)日:2012-06-14

    申请号:US13391352

    申请日:2010-08-20

    IPC分类号: C40B20/00 G06G7/58 C12Q1/68

    摘要: Methods of diagnosing and treating microbiome-associated disease or improving health using interaction network parameters are provided. Methods are provided to analyze interaction networks between microbes, and between microbes and the host, to determine important (e.g. “highly-connected”) organisms or molecules as determined by various network parameters. Methods are provided including and beyond correlation to use these “highly-connected” organisms or molecules as targets for modulation or as therapeutic agents to improve health.

    摘要翻译: 提供了使用交互网络参数诊断和治疗微生物相关疾病或改善健康的方法。 提供了用于分析微生物之间以及微生物与宿主之间的相互作用网络的方法,以确定由各种网络参数确定的重要(例如“高度连接的”)生物或分子。 提供包括和超出相关性的方法,以使用这些“高度连接”的生物或分子作为调节的靶标或作为改善健康的治疗剂。