专利检索 ap:("C. Frank Bennett" OR "Timothy A. Vickers" OR "James G. Karras" OR "Susan M. Freier") AND inv:"C. Frank Bennett" 第 1 页

1.

发明授权
Oligonucleotide compositions and methods for the modulation of the expression of B7 protein 失效
标题翻译：寡核苷酸组合物和调节B7蛋白表达的方法

公开(公告)号：US07235653B2

公开(公告)日：2007-06-26

申请号：US10641962

申请日：2003-08-15

申请人： C. Frank Bennett , Timothy A. Vickers , James G. Karras , Susan M. Freier

发明人： C. Frank Bennett , Timothy A. Vickers , James G. Karras , Susan M. Freier

IPC分类号： C07H21/04 , A61K31/70 , A01N43/04

CPC分类号： A61K31/711 , A61K38/00 , C07H21/00 , C12N15/1138 , C12N2310/31 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346 , C12N2310/3515 , Y02P20/582 , C12N2310/3525 , C12N2310/3521

摘要： Compositions and methods for the treatment of asthma with oligonucleotides which specifically hybridize with nucleic acids encoding B7 proteins.

摘要翻译： 用与编码B7蛋白的核酸特异性杂交的寡核苷酸治疗哮喘的组合物和方法。

2.

发明授权
Alteration of cellular behavior by antisense modulation of mRNA processing 有权
标题翻译：通过mRNA加工的反义调节来改变细胞行为

公开(公告)号：US06210892B1

公开(公告)日：2001-04-03

申请号：US09277020

申请日：1999-03-26

申请人： C. Frank Bennett , Stanley T. Cooke , Muthiah Manoharan , Jacqueline R. Wyatt , Brenda F. Baker , Brett P. Monia , Susan M. Freier , Robert McKay , James G. Karras

发明人： C. Frank Bennett , Stanley T. Cooke , Muthiah Manoharan , Jacqueline R. Wyatt , Brenda F. Baker , Brett P. Monia , Susan M. Freier , Robert McKay , James G. Karras

IPC分类号： C12Q168

CPC分类号： C12N15/1135 , A61K38/00 , C12N2310/11 , C12N2310/315 , C12N2310/3181 , C12N2310/321 , C12N2310/3233 , C12N2310/334 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346 , Y02P20/582 , C12N2310/3525

摘要： The present invention provides compositions and methods for controlling the behavior of a cell, tissue or organism through antisense modulation of mRNA processing, using antisense compounds which does not support cleavage of the mRNA target.

摘要翻译： 本发明提供了使用不支持mRNA靶的切割的反义化合物来控制细胞，组织或生物体通过mRNA加工反义调节的行为的组合物和方法。

3.

发明授权
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs 失效
标题翻译：用于调节小非编码RNA的低聚化合物和组合物

公开(公告)号：US07683036B2

公开(公告)日：2010-03-23

申请号：US10909125

申请日：2004-07-30

申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

IPC分类号： A61K31/70 , C07H21/04

CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/3181 , C12N2310/32 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2310/351 , C12N2310/3515 , C12N2320/11 , C12N2320/30 , C12N2320/50 , C12N2310/3525

摘要： Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

摘要翻译： 提供化合物，组合物和方法用于调节小非编码RNA的表达和功能。组合物包含靶向小的非编码RNA的寡聚化合物。还提供了使用这些化合物调节小非编码RNA以及这些RNA的下游靶标以及用于诊断和治疗与小非编码RNA相关的疾病的方法。

4.

发明申请
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs 有权
标题翻译：用于调节小非编码RNA的低聚化合物和组合物

公开(公告)号：US20090291907A1

公开(公告)日：2009-11-26

申请号：US12345891

申请日：2008-12-30

申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

IPC分类号： A61K31/7105 , C12N5/06 , C12Q1/68

CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/3181 , C12N2310/32 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2310/351 , C12N2310/3515 , C12N2320/11 , C12N2320/30 , C12N2320/50 , C12N2310/3525

摘要： Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

摘要翻译： 提供化合物，组合物和方法用于调节小非编码RNA的表达和功能。组合物包含靶向小的非编码RNA的寡聚化合物。还提供了使用这些化合物调节小非编码RNA以及这些RNA的下游靶标以及用于诊断和治疗与小非编码RNA相关的疾病的方法。

5.

发明申请
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs 有权
标题翻译：用于调节小非编码RNA的低聚化合物和组合物

公开(公告)号：US20100267813A1

公开(公告)日：2010-10-21

申请号：US12346940

申请日：2008-12-31

申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

IPC分类号： A61K31/7088 , C07H21/02

CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/3181 , C12N2310/32 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2310/351 , C12N2310/3515 , C12N2320/11 , C12N2320/30 , C12N2320/50 , C12N2310/3525

摘要： Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

摘要翻译： 提供化合物，组合物和方法用于调节小非编码RNA的表达和功能。组合物包含靶向小的非编码RNA的寡聚化合物。还提供了使用这些化合物调节小非编码RNA以及这些RNA的下游靶标以及用于诊断和治疗与小非编码RNA相关的疾病的方法。

6.

发明申请
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs 有权

公开(公告)号：US20090291906A1

公开(公告)日：2009-11-26

申请号：US12345854

申请日：2008-12-30

申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

IPC分类号： A61K31/7105 , C12N15/11 , C12N5/06 , C12Q1/68

CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/3181 , C12N2310/32 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2310/351 , C12N2310/3515 , C12N2320/11 , C12N2320/30 , C12N2320/50 , C12N2310/3525

摘要： Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

7.

发明申请
OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS 有权
标题翻译：用于调节小型非编码RNAs的低分子化合物和组合物

公开(公告)号：US20120122216A1

公开(公告)日：2012-05-17

申请号：US13359271

申请日：2012-01-26

申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

发明人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta

IPC分类号： C12N5/071

CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/3181 , C12N2310/32 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2310/351 , C12N2310/3515 , C12N2320/11 , C12N2320/30 , C12N2320/50 , C12N2310/3525

摘要： Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.

摘要翻译： 提供化合物，组合物和方法用于调节小非编码RNA的表达和功能。组合物包含靶向小的非编码RNA的寡聚化合物。还提供了使用这些化合物调节小非编码RNA以及这些RNA的下游靶标以及用于诊断和治疗与小非编码RNA相关的疾病的方法。