公开(公告)号：US20250049681A1

公开(公告)日：2025-02-13

申请号：US18808749

申请日：2024-08-19

Applicant: Colgate-Palmolive Company

Inventor： Venda Porter MALONEY ,  Vyoma Patel ,  Steven Fisher ,  André Morgan ,  Michael Prencipe ,  Stanislav Jaracz

IPC: A61K8/58 ,  A61K8/24 ,  A61K8/27 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K8/44 ,  A61Q11/00

Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.

公开(公告)号：US12194123B2

公开(公告)日：2025-01-14

申请号：US17725204

申请日：2022-04-20

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61K6/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/36 ,  A61K8/81 ,  A61Q11/00

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US20240315934A1

公开(公告)日：2024-09-26

申请号：US18732903

申请日：2024-06-04

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael Prencipe

IPC: A61K8/27 ,  A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/362 ,  A61Q11/00

CPC classification number: A61K8/27 ,  A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/362 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/92

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

公开(公告)号：US11931437B2

公开(公告)日：2024-03-19

申请号：US17301913

申请日：2021-04-19

Applicant: Colgate-Palmolive Company

Inventor： Madhuleena Bhadra ,  Michael Prencipe ,  Aarti Rege

IPC: A61K8/21 ,  A61K8/25 ,  A61K8/27 ,  A61K8/365 ,  A61Q11/00 ,  C09K3/14

CPC classification number: A61K8/21 ,  A61K8/25 ,  A61K8/27 ,  A61K8/365 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/5922 ,  C09K3/1409

Abstract: This invention relates to dentifrice compositions comprising stannous fluoride and a silica abrasive having a N2 BET surface area of less than 50 m2/g and an Einlehner hardness of from 4 to 11, as well as to methods of using these compositions.

公开(公告)号：US11813342B2

公开(公告)日：2023-11-14

申请号：US17249579

申请日：2021-03-05

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe ,  Paul Thomson ,  Rehana Begum-Gafur

IPC: A61K8/24 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/27 ,  A61K8/20

CPC classification number: A61K8/24 ,  A61K8/20 ,  A61K8/21 ,  A61K8/27 ,  A61Q11/00

Abstract: This invention relates to oral care compositions comprising zinc phosphate, a first source of stannous (e.g., stannous fluoride); and a second source of stannous, wherein the second source of stannous comprises stannous pyrophosphate, as well as to methods of using and of making these compositions.

公开(公告)号：US11260002B2

公开(公告)日：2022-03-01

申请号：US16572749

申请日：2019-09-17

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/44 ,  A61K8/43

Abstract: An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.

公开(公告)号：US20210137815A1

公开(公告)日：2021-05-13

申请号：US17248391

申请日：2021-01-22

Applicant: Colgate-Palmolive Company

Inventor： Lynette Zaidel ,  Guisheng Pan ,  Suman Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US10980720B2

公开(公告)日：2021-04-20

申请号：US16992718

申请日：2020-08-13

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/20 ,  A61K8/24 ,  A61K8/362 ,  A61K8/19

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

公开(公告)号：US10772809B2

公开(公告)日：2020-09-15

申请号：US16708646

申请日：2019-12-10

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/20 ,  A61K8/24 ,  A61K8/362 ,  A61K8/19

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

公开(公告)号：US10507171B2

公开(公告)日：2019-12-17

申请号：US16053916

申请日：2018-08-03

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Prakasarao Mandadi ,  Olivier Garot

IPC: A61K8/22 ,  A61Q11/00 ,  A61K8/81 ,  A61K8/34 ,  A61K8/25 ,  A61K8/24 ,  A61K8/86

Abstract: Described herein are oral care compositions comprising (i) a peroxide whitening agent comprising a whitening complex of crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, (ii) sodium acid pyrophosphate (Na2H2P2O7) in an amount of from 0.05 wt % to 5 wt % based on the weight of the composition, and (iii) less than 3 wt % water based on the weight of the composition.