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    System and Method for Patient Specific Modeling of Liver Tumor Ablation
    1.
    发明申请
    System and Method for Patient Specific Modeling of Liver Tumor Ablation 有权
    肝脏肿瘤消融患者特异性建模的系统和方法

    公开(公告)号：US20140136174A1

    公开(公告)日：2014-05-15

    申请号：US14071688

    申请日：2013-11-05

    申请人： Chloe Audigier ,  Tommaso Mansi ,  Viorel Mihalef ,  Ali Kamen ,  Dorin Comaniciu ,  Puneet Sharma ,  Saikiran Rapaka ,  Herve Delingette ,  Nicholas Ayache

    发明人： Chloe Audigier ,  Tommaso Mansi ,  Viorel Mihalef ,  Ali Kamen ,  Dorin Comaniciu ,  Puneet Sharma ,  Saikiran Rapaka ,  Herve Delingette ,  Nicholas Ayache

    IPC分类号： G06F19/12

    CPC分类号： G16H50/50 ,  G06F19/00 ,  G06F19/3481 ,  G09B23/30

    摘要： A method and system for tumor ablation planning and guidance based on a patient-specific model of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the venous system of the liver. Cellular necrosis in the liver is simulated based on the simulated heat diffusion. A visualization of a simulated necrosis region is generated and displayed to the user for decision making and optimal therapy planning and guidance.

    摘要翻译： 公开了一种基于肝肿瘤消融的患者特异性模型的肿瘤消融计划和指导的方法和系统。 根据患者的3D医学图像数据估计肝脏和肝脏循环系统的患者特异性解剖模型。 根据患者特异性解剖模型模拟肝脏和肝脏循环系统的血流。 基于虚拟消融探针位置和肝脏和肝脏静脉系统中的模拟血流模拟了消融引起的热扩散。 基于模拟热扩散模拟肝脏细胞坏死。 生成模拟坏死区域的可视化，并向用户显示决策和最佳治疗计划和指导。

    Apparatus for simulating the deformation of materials, notably of soft body tissues
    3.
    发明授权
    Apparatus for simulating the deformation of materials, notably of soft body tissues 有权
    用于模拟材料变形的装置，特别是软体组织的变形

    公开(公告)号：US07239992B2

    公开(公告)日：2007-07-03

    申请号：US10061455

    申请日：2002-02-04

    申请人： Nicholas Ayache ,  Herve Delingette ,  Guillaume Picinbono

    发明人： Nicholas Ayache ,  Herve Delingette ,  Guillaume Picinbono

    IPC分类号： G06G7/48 ,  G06F3/00 ,  G06T15/00 ,  G06T17/00 ,  G09G5/00 ,  A61H1/00

    CPC分类号： G06T17/20 ,  G06T13/20

    摘要： The invention relates to the simulation of the deformation of materials, notably of soft body tissues. An apparatus comprises a memory (MEM, NT) storing data as to the position of an object, recorded at the vertices of a grid pattern, and data for force to be exerted on the object. A computer (μP, MT) evaluates new positions of the vertices, as a function of a force exerted globally and mechanical parameters of the material. According to the invention, this computer comprises a module for calculating, for each mesh, a deviation between the current length of an edge and its previous length, and the force data at each vertex of the mesh. Another module calculates, for each vertex, new positional data relating to this vertex as a function of the forces exerted thereon and its previous position.

    摘要翻译： 本发明涉及材料变形的模拟，特别是软体组织的变形。 存储器（MEM，NT）存储关于记录在网格图案的顶点的物体的位置的数据，以及用于施加在物体上的力的数据。 计算机（muP，MT）根据全局施加的力和材料的机械参数来评估顶点的新位置。 根据本发明，该计算机包括用于针对每个网格计算边缘的当前长度与其先前长度之间的偏差以及网格的每个顶点处的力数据的模块。 另一个模块针对每个顶点计算与该顶点相关的新位置数据，作为施加于其上的力及其先前位置的函数。