System and Method for Patient Specific Modeling of Liver Tumor Ablation
    5.
    发明申请
    System and Method for Patient Specific Modeling of Liver Tumor Ablation 有权
    肝脏肿瘤消融患者特异性建模的系统和方法

    公开(公告)号:US20140136174A1

    公开(公告)日:2014-05-15

    申请号:US14071688

    申请日:2013-11-05

    IPC分类号: G06F19/12

    摘要: A method and system for tumor ablation planning and guidance based on a patient-specific model of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the venous system of the liver. Cellular necrosis in the liver is simulated based on the simulated heat diffusion. A visualization of a simulated necrosis region is generated and displayed to the user for decision making and optimal therapy planning and guidance.

    摘要翻译: 公开了一种基于肝肿瘤消融的患者特异性模型的肿瘤消融计划和指导的方法和系统。 根据患者的3D医学图像数据估计肝脏和肝脏循环系统的患者特异性解剖模型。 根据患者特异性解剖模型模拟肝脏和肝脏循环系统的血流。 基于虚拟消融探针位置和肝脏和肝脏静脉系统中的模拟血流模拟了消融引起的热扩散。 基于模拟热扩散模拟肝脏细胞坏死。 生成模拟坏死区域的可视化,并向用户显示决策和最佳治疗计划和指导。

    Robotic Navigated Nuclear Probe Imaging
    6.
    发明申请
    Robotic Navigated Nuclear Probe Imaging 有权
    机器人导航核探针成像

    公开(公告)号:US20130261446A1

    公开(公告)日:2013-10-03

    申请号:US13881209

    申请日:2011-11-10

    IPC分类号: A61B6/00

    摘要: Robotic navigation is provided for nuclear probe imaging. Using a three-dimensional scanner (19), the surface of a patient is determined (42). A calibrated robotic system positions (48) a nuclear probe about the patient based on the surface. The positioning (48) may be without contacting the patient and the surface may be used in reconstruction to account for spacing of the probe from the patient. By using the robotic system for positioning (48), the speed, resolution and/or quality of the reconstructed image may be predetermined, user settable, and/or improved compared to manual scanning. The reconstruction (52) may be more computationally efficient by providing for regular spacing of radiation detection locations within the volume

    摘要翻译: 提供机器人导航用于核探针成像。 使用三维扫描器(19),确定患者的表面(42)。 校准的机器人系统基于表面定位(48)关于患者的核探针。 定位(48)可以不与患者接触,并且可以在重建中使用表面以考虑探针与患者的间隔。 通过使用用于定位的机器人系统(48),与手动扫描相比,重建图像的速度,分辨率和/或质量可以是预定的,用户可设置的和/或改进的。 通过提供体积内的辐射检测位置的规则间隔,重建(52)可以更有计算效率

    NETWORK CYCLE FEATURES IN RELATIVE NEIGHBORHOOD GRAPHS
    7.
    发明申请
    NETWORK CYCLE FEATURES IN RELATIVE NEIGHBORHOOD GRAPHS 有权
    网络周期特征在相对邻里图

    公开(公告)号:US20130243292A1

    公开(公告)日:2013-09-19

    申请号:US13780370

    申请日:2013-02-28

    IPC分类号: G06T7/00

    摘要: Methods for analyzing biomedical data include: (a) obtaining macroscopic imaging data; (b) obtaining histopathological imaging data; (c) executing a parallel algorithm stored on a non-transient computer-readable medium to compute one or a plurality of network cycle features of a relative neighborhood graph derived from the histopathological imaging data; (d) registering the macroscopic imaging data and the histopathological imaging data; and (e) correlating the macroscopic imaging data and the network cycle features. Systems for analyzing biomedical data and computer readable storage media are described.

    摘要翻译: 分析生物医学数据的方法包括:(a)获取宏观成像数据; (b)获得组织病理学成像数据; (c)执行存储在非瞬时计算机可读介质上的并行算法,以计算从组织病理学成像数据导出的相对邻域图的一个或多个网络周期特征; (d)记录宏观成像数据和组织病理学成像数据; 和(e)将宏观成像数据和网络周期特征相关联。 描述了用于分析生物医学数据和计算机可读存储介质的系统。

    Method and System for Multi-Scale Anatomical and Functional Modeling of Coronary Circulation
    8.
    发明申请
    Method and System for Multi-Scale Anatomical and Functional Modeling of Coronary Circulation 审中-公开
    冠状动脉循环多尺度解剖与功能建模方法与系统

    公开(公告)号:US20130132054A1

    公开(公告)日:2013-05-23

    申请号:US13672781

    申请日:2012-11-09

    IPC分类号: G06F19/12

    摘要: A method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. A patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. A multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. Blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. Hemodynamic quantities, such as fractional flow reserve (FFR), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning.

    摘要翻译: 公开了一种用于冠状循环多尺度解剖和功能建模的方法和系统。 冠状动脉和心脏的患者特异性解剖模型由患者的医学图像数据产生。 基于患者特异性解剖模型产生冠状动脉循环的多尺度功能模型。 使用冠状动脉循环的多尺度功能模型在至少一个冠状动脉的至少一个狭窄区域中模拟血流量。 计算血流动力学量,例如分数流量储备(FFR),以确定狭窄的功能评估,并使用冠状动脉循环的多尺度函数模型进行虚拟干预模拟,以进行决策支持和干预计划。

    HIERARCHICAL ATLAS-BASED SEGMENTATION
    9.
    发明申请
    HIERARCHICAL ATLAS-BASED SEGMENTATION 有权
    基于分层的基于ATLAS的分类

    公开(公告)号:US20110216954A1

    公开(公告)日:2011-09-08

    申请号:US13033730

    申请日:2011-02-24

    IPC分类号: G06K9/32 G06K9/00

    摘要: A method for segmenting an image includes registering an annotated template image to an acquired reference image using only rigid transformations to define a transformation function relating the annotated template image to the acquired reference image. The defined transformation function is refined by registering the annotated template image to the acquired reference image using only affine transformations. The refined transformation function is further refined by registering the annotated template image to the acquired reference image using only multi-affine transformations. The twice refined transformation function is further refined by registering the annotated template image to the acquired reference image using deformation transformations.

    摘要翻译: 用于分割图像的方法包括使用刚性变换将注释的模板图像注册到所获取的参考图像,以定义将所注释的模板图像与所获取的参考图像相关联的变换函数。 通过仅使用仿射变换将注释的模板图像注册到所获取的参考图像来改进定义的变换函数。 通过仅使用多仿射变换将所注释的模板图像注册到所获取的参考图像,进一步改进了精细变换函数。 通过使用变形变换将注释的模板图像注册到所获取的参考图像来进一步改进两次精制转换函数。