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公开(公告)号:US07638480B2
公开(公告)日:2009-12-29
申请号:US10510876
申请日:2003-03-26
CPC分类号: A61K38/215 , A61K38/177 , A61K38/179 , A61K45/06 , A61K48/00 , A61K2300/00
摘要: The invention relates to the use of osteoprotegerin for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
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公开(公告)号:US20060003928A1
公开(公告)日:2006-01-05
申请号:US10510876
申请日:2003-03-26
IPC分类号: A61K38/17
CPC分类号: A61K38/215 , A61K38/177 , A61K38/179 , A61K45/06 , A61K48/00 , A61K2300/00
摘要: The invention relates to the use of osteoprotegerin for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
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3.USE OF SARP-1 FOR THE TREATMENT AND/OR PREVENTION OF SCLERODERMA 失效
标题翻译: 使用SARP-1治疗和/或预防SCLERODERMA公开(公告)号:US20080107627A1
公开(公告)日:2008-05-08
申请号:US11961033
申请日:2007-12-20
IPC分类号: A61K38/00 , A61K39/395 , A61K38/21 , A61P17/00
CPC分类号: A61K38/215 , A61K38/00 , A61K48/00 , C07K14/52 , A61K2300/00
摘要: The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
摘要翻译: 本发明涉及SARP-1在制备用于治疗和/或预防硬皮病,特别是系统性硬化症的药物中的应用。
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4.Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease 失效
标题翻译: 使用骨保护素治疗和/或预防纤维化疾病公开(公告)号:US20050143301A1
公开(公告)日:2005-06-30
申请号:US10966845
申请日:2004-10-15
CPC分类号: A61K38/177 , A61K47/60 , A61K47/6813
摘要: The invention relates to the use of osteoprotegerin for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
摘要翻译: 本发明涉及骨保护素用于治疗和/或预防纤维化疾病,特别是硬皮病的用途。
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5.
公开(公告)号:US07655628B2
公开(公告)日:2010-02-02
申请号:US11961033
申请日:2007-12-20
IPC分类号: A61K38/00
CPC分类号: A61K38/215 , A61K38/00 , A61K48/00 , C07K14/52 , A61K2300/00
摘要: The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
摘要翻译: 本发明涉及SARP-1在制备用于治疗和/或预防硬皮病,特别是系统性硬化症的药物中的应用。
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6.Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease 失效
标题翻译: 使用骨保护素治疗和/或预防纤维化疾病公开(公告)号:US07585840B2
公开(公告)日:2009-09-08
申请号:US10966845
申请日:2004-10-15
CPC分类号: A61K38/177 , A61K47/60 , A61K47/6813
摘要: The invention relates to the use of osteoprotegerin for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
摘要翻译: 本发明涉及骨保护素用于治疗和/或预防纤维化疾病,特别是硬皮病的用途。
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7.
公开(公告)号:US07341995B2
公开(公告)日:2008-03-11
申请号:US10432256
申请日:2001-11-30
IPC分类号: A61K38/00
CPC分类号: A61K38/215 , A61K38/00 , A61K48/00 , C07K14/52 , A61K2300/00
摘要: The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
摘要翻译: 本发明涉及SARP-1在制备用于治疗和/或预防硬皮病,特别是系统性硬化症的药物中的应用。
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8.
公开(公告)号:US20050113291A1
公开(公告)日:2005-05-26
申请号:US10432256
申请日:2001-11-30
IPC分类号: C12N15/09 , A61K35/12 , A61K38/00 , A61K38/17 , A61K38/21 , A61K39/395 , A61K45/00 , A61K45/06 , A61K48/00 , A61P1/16 , A61P9/10 , A61P11/00 , A61P19/00 , A61P21/00 , A61P29/00 , A61P43/00 , C07K14/47 , C07K14/52
CPC分类号: A61K38/215 , A61K38/00 , A61K48/00 , C07K14/52 , A61K2300/00
摘要: The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
摘要翻译: 本发明涉及SARP-1在制备用于治疗和/或预防硬皮病,特别是系统性硬化症的药物中的应用。
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公开(公告)号:US07803910B2
公开(公告)日:2010-09-28
申请号:US11814389
申请日:2006-01-24
IPC分类号: C07K14/00
CPC分类号: A61K49/0008 , A61K38/00
摘要: The present invention relates to sCD164 variants and therapeutic uses thereof, in particular for treating or preventing inflammatory or autoimmune disorders.
摘要翻译: 本发明涉及sCD164变体及其治疗用途,特别是用于治疗或预防炎性或自身免疫性疾病。
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公开(公告)号:US20100048467A1
公开(公告)日:2010-02-25
申请号:US12159541
申请日:2006-01-12
申请人: Mark Douglas Davies , Christopher Benjamin Phelps , Richard Joseph Fagan , Christine Power , Melanie Yorke , Mark Ibberson , Yan Lavrovsky
发明人: Mark Douglas Davies , Christopher Benjamin Phelps , Richard Joseph Fagan , Christine Power , Melanie Yorke , Mark Ibberson , Yan Lavrovsky
IPC分类号: A61K38/16 , A61K31/7088 , A61P35/00
CPC分类号: A61K38/18
摘要: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
摘要翻译: 本发明涉及一种新型蛋白质(INSP002),其被鉴定为分泌型蛋白质,其是胱氨酸 - 结折叠细胞因子超家族的丹氏家族的成员,并且使用该蛋白质和来自编码基因的核酸序列 诊断,预防和治疗疾病。
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