公开(公告)号：US20220378678A1

公开(公告)日：2022-12-01

申请号：US17825372

申请日：2022-05-26

Applicant: Colgate-Palmolive Company

Inventor： Murilo Nogueira NAKAJIMA ,  Saide TANG ,  Enzo UTIMA ,  Guofeng XU ,  Paloma PIMENTA

IPC: A61K8/43 ,  A61K8/73 ,  A61Q11/00

Abstract: This application provides, among other things, oral care compositions where the addition of a stabilizing amount of a nonionic gelling and thickening agent, (e.g., hydroxyethyl cellulose (HEC)) and an effective amount of a zwitterionic surfactant (e.g., a betaine zwitterionic surfactant) (e.g., cocamidopropyl betaine), to formulations comprising a bisbiguanide (e.g., chlorhexidine (CHX)) agent, and optionally an effective amount of abrasive silica, allows for proper structure and consistency to the formulation and to allow it to be used as a gel or a toothpaste to facility delivery of chlorhexidine, among other actives, to the teeth or gums with acceptable stability and foaming.

公开(公告)号：US20210307886A1

公开(公告)日：2021-10-07

申请号：US17354245

申请日：2021-06-22

Applicant: Colgate-Palmolive Company

Inventor： Patrik JOHANSSON ,  Guofeng XU ,  Gerald GONTARZ ,  Robert MOSKOVICH ,  Daniel WAINLESS

IPC: A61C17/22 ,  A46B15/00 ,  A61C17/32 ,  A46B11/00 ,  A61C17/34 ,  C25B1/00 ,  C25B1/26 ,  C25B9/17

Abstract: A powered toothbrush includes a handle, a power source disposed in the handle, a head including a cavity disposed at a distal end of the handle, an electrically conducting element disposed in the cavity and electrically connected to the power source, and a movable cleaning element connected to the head and movable relative to the cavity. The movable cleaning element includes a tooth cleaning support member, a tooth cleaning element mounted on the support member, and a ferromagnetic member. Application of an electrical current to the electrically conducting element generates a magnetic field at the electrically conducting element. The magnetic field selectively at least one of attracts and repels the ferromagnetic member to move the movable cleaning element relative to the electrically conducting element.

公开(公告)号：US20190038535A1

公开(公告)日：2019-02-07

申请号：US15670009

申请日：2017-08-07

Applicant: Colgate-Palmolive Company

Inventor： Chun Huang ,  Guofeng XU ,  Cajetan DOGO-ISONAGIE

IPC: A61K8/49 ,  A61K8/21 ,  A61K8/22 ,  A61Q11/00

Abstract: A whitening composition and methods for whitening teeth and generating a whitening agent with the same are provided. The whitening composition may include an orally acceptable vehicle, a source of hydrogen peroxide that provides hydrogen peroxide, and a cyclic anhydride that generates a whitening agent with the hydrogen peroxided provided by the source of hydrogen peroxide. The whitening agent may be a peracid, such as a succinic peracid.

公开(公告)号：US20170128181A1

公开(公告)日：2017-05-11

申请号：US15344450

申请日：2016-11-04

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Rong DONG ,  Guofeng XU ,  Shaotang YUAN ,  James THOMAS ,  Kevern FRASER

IPC: A61C19/06 ,  A61M11/00 ,  A61C3/00

CPC classification number: A61C19/063 ,  A61C3/005 ,  A61C5/62 ,  A61C19/066 ,  A61K6/0017 ,  A61K6/0091 ,  A61K6/0094 ,  A61K6/0215 ,  A61K6/0235 ,  A61M11/006

Abstract: Disclosed is a method of forming a uniform coating onto a tooth surface, which method includes: forming droplets by spraying an orally acceptable coating material through a spray nozzle, wherein the droplets have a volume-averaged droplet size of about 1 μm to about 100 μm, wherein a spray including the droplets travels from a tip of the spray nozzle towards the tooth surface at a spray rate of less than about 10 milliliters/minute and wherein the droplets include a film-forming polymer, a therapeutic agent and/or a cosmetic agent; and depositing the droplets onto the tooth surface to thereby form a uniform coating.

公开(公告)号：US20240050332A1

公开(公告)日：2024-02-15

申请号：US18258248

申请日：2021-12-20

Applicant: Colgate-Palmolive Company

Inventor： Carl MYERS ,  Guofeng XU ,  Shaoyi ZHANG ,  Saide TANG

IPC: A61K8/21 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/55

CPC classification number: A61K8/21 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/55

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride, and/or stannous chloride, and/or stannous pyrophosphate and potassium salts, with a polyphosphate source, wherein the polyphosphate source comprises three or more phosphate moieties or units, in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor.

公开(公告)号：US20200297594A1

公开(公告)日：2020-09-24

申请号：US16062147

申请日：2015-12-17

Applicant: Colgate-Palmolive Company

Inventor： Cajetan DOGO-ISONAGIE ,  Guofeng XU

IPC: A61K8/22 ,  A61K8/38 ,  A61K8/41 ,  A61K8/46 ,  A61K8/73 ,  A61Q11/02

Abstract: Provided is a tooth whitening system, including at least one whitening agent disposed in a first storage chamber, and least one bleach activator disposed in a second storage chamber. t,?

公开(公告)号：US20200206123A1

公开(公告)日：2020-07-02

申请号：US16715237

申请日：2019-12-16

Applicant: Colgate-Palmolive Company

Inventor： Shaotang YUAN ,  Guofeng XU ,  Junhong MAO

IPC: A61K8/91 ,  A61K8/81 ,  A61K8/86 ,  A61K8/90 ,  A61K8/37 ,  A61K8/34 ,  A61K8/04 ,  A61Q11/00

Abstract: An oral care composition and methods for preparing the oral care composition are disclosed. The oral care composition may include a carrier and a structure-building agent. The carrier may be present in an amount of from about 0.01 wt % to about 99 wt %. The structure-building agent may include a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers (PCA-PVA-PEG), and may be present in an amount of from about 0.01 wt % to about 60 wt %, based on a total weight of the oral care composition.

公开(公告)号：US20190388326A1

公开(公告)日：2019-12-26

申请号：US16564693

申请日：2019-09-09

Applicant: Colgate-Palmolive Company

Inventor： Shaotang YUAN ,  Guofeng XU ,  Jennifer GRONLUND ,  Robert DICOSIMO ,  Sharon HAYNIE ,  Mark PAYNE

IPC: A61K8/66 ,  A61K8/25 ,  A61Q11/00 ,  A61K8/90 ,  A61K8/81 ,  A61K8/37 ,  A61K8/22

Abstract: An oral care composition including an enzyme and an anhydrous matrix that at least partially stabilizes the enzyme. The anhydrous matrix includes a source of hydrogen peroxide, an acyl donor, a non-aqueous anhydrous liquid, and a thickener.

公开(公告)号：US20180168993A1

公开(公告)日：2018-06-21

申请号：US15838679

申请日：2017-12-12

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Guofeng XU ,  Robert DICOSIMO ,  Sharon HAYNIE

IPC: A61K8/81 ,  A61Q11/00 ,  A61K8/86 ,  A61K8/37

CPC classification number: A61K8/8182 ,  A61K8/22 ,  A61K8/37 ,  A61K8/375 ,  A61K8/8176 ,  A61K8/86 ,  A61K2800/48 ,  A61Q11/00

Abstract: Described herein are oral care compositions, comprising a peroxydone complex, a dispersant, and a polyvinylpyrrolidone copolymer structure-building agent.

公开(公告)号：US20180168983A1

公开(公告)日：2018-06-21

申请号：US15840050

申请日：2017-12-13

Applicant: Colgate-Palmolive Company

Inventor： Shyamala PILLAI ,  Guofeng XU ,  LaTonya KILPATRICK-LIVERMAN ,  Xiang CHEN ,  Suman CHOPRA ,  Robert DICOSIMO ,  Mark S. PAYNE ,  Mahmoud HASSAN

IPC: A61K8/66 ,  A61Q11/00 ,  A61K8/22 ,  A61K8/37 ,  A61K8/81 ,  A61K8/06 ,  A61C19/06

CPC classification number: A61K8/66 ,  A61C19/066 ,  A61K8/06 ,  A61K8/22 ,  A61K8/31 ,  A61K8/37 ,  A61K8/375 ,  A61K8/44 ,  A61K8/442 ,  A61K8/4973 ,  A61K8/8147 ,  A61K8/817 ,  A61K8/8176 ,  A61K2800/48 ,  A61K2800/882 ,  A61Q11/00

Abstract: An oral care composition including a hydrophobic phase and a hydrophilic phase is disclosed. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor, and the hydrophilic phase may include an enzyme having perhydrolytic activity that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.