公开(公告)号：US20060271030A1

公开(公告)日：2006-11-30

申请号：US11403038

申请日：2006-04-11

申请人： Dan Francis ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Kenneth Horne ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

发明人： Dan Francis ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Kenneth Horne ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

IPC分类号： A61B18/04 ,  A61B18/18

CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00504 ,  A61B2017/00557 ,  A61B2017/00561 ,  A61B2017/00575 ,  A61B2017/22069 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/1407 ,  A61B2090/061 ,  A61M25/0069 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1054

摘要： Methods for treating anatomic tissue defects such as a patent foramen ovate generally involve positioning a distal end of a catheter device at the site of the defect, exposing a housing and energy transmission member from the distal end of the catheter, engaging the housing with tissues at the site of the defect, applying suction or other approximating tool to the tissue via the housing to bring the tissue together, and applying energy to the tissue with the energy transmission member or to deliver a clip or fixation device to substantially close the defect. Apparatus generally include a catheter body, a housing extending from a distal end of the catheter body for engaging tissue at the site of the defect, and further adapted to house a fusing or fixation device such as an energy transmission member adjacent a distal end of the housing, or a clip or fixation delivery element.

摘要翻译： 用于治疗解剖组织缺陷的方法，例如卵形专利孔通常涉及将导管装置的远端定位在缺损部位，使外壳和能量传递构件从导管的远端露出，使壳体与组织接合 通过外壳向组织施加吸力或其它近似工具以将组织带到一起，以及用能量传递构件向组织施加能量，或者输送夹子或固定装置以基本上封闭缺陷。 装置通常包括导管主体，从导管主体的远端延伸的壳体，用于接合缺损位置处的组织，并且还适于容纳定影或固定装置，例如邻近于所述导管主体的远端的能量传递构件 外壳，或夹子或固定传递元件。

公开(公告)号：US20060271089A1

公开(公告)日：2006-11-30

申请号：US11402489

申请日：2006-04-11

申请人： Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Kenneth Horne ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

发明人： Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Kenneth Horne ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

IPC分类号： A61M29/00

CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00504 ,  A61B2017/00557 ,  A61B2017/00561 ,  A61B2017/00575 ,  A61B2017/22069 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/1407 ,  A61B2090/061 ,  A61M25/0069 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1054

摘要： Methods for treating anatomic tissue defects such as a patent foramen ovale generally involve positioning a distal end of a catheter device at the site of the defect, exposing a housing and energy transmission member from the distal end of the catheter, engaging the housing with tissues at the site of the defect, applying suction or other approximating tool to the tissue via the housing to bring the tissue together, and applying energy to the tissue with the energy transmission member or to deliver a clip or fixation device to substantially close the defect. Apparatus generally include a catheter body, a housing extending from a distal end of the catheter body for engaging tissue at the site of the defect, and further adapted to house a fusing or fixation device such as an energy transmission member adjacent a distal end of the housing, or a clip or fixation delivery element.

摘要翻译： 用于治疗解剖组织缺陷的方法，例如卵孔卵孔通常涉及将导管装置的远端定位在缺损部位，使外壳和能量传递构件从导管的远端露出，使壳体与组织接合 通过外壳向组织施加吸力或其它近似工具以将组织带到一起，以及用能量传递构件向组织施加能量，或者输送夹子或固定装置以基本上封闭缺陷。 装置通常包括导管主体，从导管主体的远端延伸的壳体，用于接合缺损位置处的组织，并且还适于容纳定影或固定装置，例如邻近于所述导管主体的远端的能量传递构件 外壳，或夹子或固定传递元件。

公开(公告)号：US20060271040A1

公开(公告)日：2006-11-30

申请号：US11403052

申请日：2006-04-11

申请人： Kenneth Horne ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

发明人： Kenneth Horne ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Lucia Kim ,  Uday Kumar ,  Doug Sutton ,  Miriam Taimisto ,  Andy Uchida

IPC分类号： A61B18/18

CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00504 ,  A61B2017/00557 ,  A61B2017/00561 ,  A61B2017/00575 ,  A61B2017/22069 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/1407 ,  A61B2090/061 ,  A61M25/0069 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1054

摘要： Methods for treating anatomic tissue defects such as a patent foramen ovale generally involve positioning a distal end of a catheter device at the site of the defect, exposing a housing and energy transmission member from the distal end of the catheter, engaging the housing with tissues at the site of the defect, applying suction or other approximating tool to the tissue via the housing to bring the tissue together, and applying energy to the tissue with the energy transmission member or to deliver a clip or fixation device to substantially close the defect. Apparatus generally include a catheter body, a housing extending from a distal end of the catheter body for engaging tissue at the site of the defect, and further adapted to house a fusing or fixation device such as an energy transmission member adjacent a distal end of the housing, or a clip or fixation delivery element.

摘要翻译： 用于治疗解剖组织缺陷的方法，例如卵孔卵孔通常涉及将导管装置的远端定位在缺损部位，使外壳和能量传递构件从导管的远端露出，使壳体与组织接合 通过外壳向组织施加吸力或其它近似工具以将组织带到一起，以及用能量传递构件向组织施加能量，或者输送夹子或固定装置以基本上封闭缺陷。 装置通常包括导管主体，从导管主体的远端延伸的壳体，用于接合缺损位置处的组织，并且还适于容纳定影或固定装置，例如邻近于所述导管主体的远端的能量传递构件 外壳，或夹子或固定传递元件。

公开(公告)号：US08109274B2

公开(公告)日：2012-02-07

申请号：US11403052

申请日：2006-04-11

申请人： Kenneth Horne ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Lucia Kim ,  Uday N. Kumar ,  Doug Sutton ,  Miriam H. Taimisto ,  Andy Uchida

发明人： Kenneth Horne ,  Jose Alejandro ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Lucia Kim ,  Uday N. Kumar ,  Doug Sutton ,  Miriam H. Taimisto ,  Andy Uchida

IPC分类号： A61B19/00

CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00504 ,  A61B2017/00557 ,  A61B2017/00561 ,  A61B2017/00575 ,  A61B2017/22069 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/1407 ,  A61B2090/061 ,  A61M25/0069 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1054

摘要： Methods for treating anatomic tissue defects such as a patent foramen ovale generally involve positioning a distal end of a catheter device at the site of the defect, exposing a housing and energy transmission member from the distal end of the catheter, engaging the housing with tissues at the site of the defect, applying suction or other approximating tool to the tissue via the housing to bring the tissue together, and applying energy to the tissue with the energy transmission member or to deliver a clip or fixation device to substantially close the defect. Apparatus generally include a catheter body, a housing extending from a distal end of the catheter body for engaging tissue at the site of the defect, and further adapted to house a fusing or fixation device such as an energy transmission member adjacent a distal end of the housing, or a clip or fixation delivery element.

摘要翻译： 用于治疗解剖组织缺陷的方法，例如卵孔卵孔通常涉及将导管装置的远端定位在缺损部位，使外壳和能量传递构件从导管的远端露出，使壳体与组织接合 通过外壳向组织施加吸力或其它近似工具以将组织带到一起，以及用能量传递构件向组织施加能量，或者输送夹子或固定装置以基本上封闭缺陷。 装置通常包括导管主体，从导管主体的远端延伸的壳体，用于接合缺损位置处的组织，并且还适于容纳定影或固定装置，例如邻近于所述导管主体的远端的能量传递构件 外壳，或夹子或固定传递元件。

公开(公告)号：US20070123851A1

公开(公告)日：2007-05-31

申请号：US11613415

申请日：2006-12-20

申请人： Jose Alejandro ,  Mark Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday Kumar ,  William Malecki ,  Miriam Taimisto ,  Venkata Vegesna

发明人： Jose Alejandro ,  Mark Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday Kumar ,  William Malecki ,  Miriam Taimisto ,  Venkata Vegesna

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B17/2202 ,  A61B18/02 ,  A61B18/08 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00575 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1407 ,  A61B2018/143 ,  A61B2018/144 ,  A61B2018/1467 ,  A61B2090/3782 ,  A61B2090/3929

摘要： Methods and apparatus for treatment of layered tissue defects such as a patent foramen ovale provide for applying energy to tissues adjacent to the PFO with a closure device that substantially closes the PFO. Apparatus generally includes an elongate flexible member having a proximal end and a distal end and an energy transmission member deployable from the elongate flexible member. The energy transmission member applies energy to the layered tissue defect at a first position and a second position adjacent to the first position so as to substantially close the layered tissue defect along at least a portion of the defect. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating, direct heat energy, cryogenic or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗层状组织缺陷（例如卵孔卵孔专利）的方法和装置提供了使用基本上封闭PFO的闭合装置向PFO附近的组织施加能量。 设备通常包括细长的柔性构件，其具有近端和远端以及能够从细长柔性构件展开的能量传递构件。 能量传递部件在与第一位置相邻的第一位置和第二位置处向层状组织缺损施加能量，以沿着缺损的至少一部分基本上封闭层状组织缺损。 应用能量可以是单极性或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热，直接热能，低温等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US20070123852A1

公开(公告)日：2007-05-31

申请号：US11613422

申请日：2006-12-20

申请人： Mark Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday Kumar ,  William Malecki ,  Miriam Taimisto

发明人： Mark Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday Kumar ,  William Malecki ,  Miriam Taimisto

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of layered tissue defects having a majority of the surfaces of the defect layers in contact generally involve use of a catheter having at least one energy transmission member at its distal end. The distal end of the apparatus also typically has a force applying member which can apply a force to the tissue defect. Often this force is a lateral force or vacuum which helps the tissue to appose itself. An exemplary method of closing a patent foramen ovale (PFO) involves positioning a closure device between layers of the PFO. Energy is then applied to the layered tissue defect with the closure device so as to substantially close the tissue defect. The energy is often monopolar or bipolar radiofrequency energy. A force may also be applied by the closure device to the layered tissue defect so as to bring the layered tissue defect together.

摘要翻译： 用于治疗具有接触缺陷层的大部分表面的层状组织缺陷的方法和装置通常涉及在其远端使用具有至少一个能量传递构件的导管。 该装置的远端通常还具有可施加力到组织缺损的施力部件。 这种力通常是侧向力或真空，有助于组织自身。 闭合卵孔卵泡（PFO）的示例性方法涉及将闭合装置定位在PFO的层之间。 然后用闭合装置将能量施加到层状组织缺陷，以便基本上封闭组织缺损。 能量通常是单极或双极射频能量。 还可以通过闭合装置将力施加到层状组织缺陷，以使层状组织缺陷在一起。

公开(公告)号：US07972330B2

公开(公告)日：2011-07-05

申请号：US11613415

申请日：2006-12-20

申请人： Jose Alejandro ,  Mark E. Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday N. Kumar ,  William Malecki ,  Miriam H. Taimisto ,  Venkata Vegesna

发明人： Jose Alejandro ,  Mark E. Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday N. Kumar ,  William Malecki ,  Miriam H. Taimisto ,  Venkata Vegesna

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B17/2202 ,  A61B18/02 ,  A61B18/08 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00575 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1407 ,  A61B2018/143 ,  A61B2018/144 ,  A61B2018/1467 ,  A61B2090/3782 ,  A61B2090/3929

摘要： Methods and apparatus for treatment of layered tissue defects such as a patent foramen ovale provide for applying energy to tissues adjacent to the PFO with a closure device that substantially closes the PFO. Apparatus generally includes an elongate flexible member having a proximal end and a distal end and an energy transmission member deployable from the elongate flexible member. The energy transmission member applies energy to the layered tissue defect at a first position and a second position adjacent to the first position so as to substantially close the layered tissue defect along at least a portion of the defect. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating, direct heat energy, cryogenic or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗层状组织缺陷（例如卵孔卵孔专利）的方法和装置提供了使用基本上封闭PFO的闭合装置向PFO附近的组织施加能量。 设备通常包括细长的柔性构件，其具有近端和远端以及能够从细长柔性构件展开的能量传递构件。 能量传递部件在与第一位置相邻的第一位置和第二位置处向层状组织缺损施加能量，以沿着缺损的至少一部分基本上封闭层状组织缺损。 应用能量可以是单极性或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热，直接热能，低温等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US08021362B2

公开(公告)日：2011-09-20

申请号：US11613422

申请日：2006-12-20

申请人： Mark E. Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday N. Kumar ,  William Malecki ,  Miriam H. Taimisto

发明人： Mark E. Deem ,  Erik Engelson ,  Dominique Filloux ,  Dan Francis ,  Hanson Gifford ,  Kenneth Horne ,  Uday N. Kumar ,  William Malecki ,  Miriam H. Taimisto

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of layered tissue defects having a majority of the surfaces of the defect layers in contact generally involve use of a catheter having at least one energy transmission member at its distal end. The distal end of the apparatus also typically has a force applying member which can apply a force to the tissue defect. Often this force is a lateral force or vacuum which helps the tissue to appose itself. An exemplary method of closing a patent foramen ovale (PFO) involves positioning a closure device between layers of the PFO. Energy is then applied to the layered tissue defect with the closure device so as to substantially close the tissue defect. The energy is often monopolar or bipolar radiofrequency energy. A force may also be applied by the closure device to the layered tissue defect so as to bring the layered tissue defect together.

摘要翻译： 用于治疗具有接触缺陷层的大部分表面的层状组织缺陷的方法和装置通常涉及在其远端使用具有至少一个能量传递构件的导管。 该装置的远端通常还具有可施加力到组织缺损的施力部件。 这种力通常是侧向力或真空，有助于组织自身。 闭合卵孔卵泡（PFO）的示例性方法涉及将闭合装置定位在PFO的层之间。 然后用闭合装置将能量施加到层状组织缺陷，以便基本上封闭组织缺损。 能量通常是单极或双极射频能量。 还可以通过闭合装置将力施加到层状组织缺陷，以使层状组织缺陷在一起。

公开(公告)号：US4994069A

公开(公告)日：1991-02-19

申请号：US265908

申请日：1988-11-02

申请人： Mark Ritchart ,  Mike Mariant ,  Ivan Sepetka ,  Erik Engelson

发明人： Mark Ritchart ,  Mike Mariant ,  Ivan Sepetka ,  Erik Engelson

IPC分类号： A61B17/12 ,  A61B19/00 ,  A61F2/00 ,  A61F2/01

CPC分类号： A61B17/12109 ,  A61B17/12022 ,  A61B17/12145 ,  A61B17/12186 ,  A61F2/01 ,  A61B2017/1205 ,  A61B90/39 ,  A61F2002/016 ,  A61F2002/3008 ,  A61F2002/30093 ,  A61F2210/0019 ,  A61F2250/0098

摘要： A flexible, preferably coiled wire for use in small-vessel vaso-occlusion. The wire has a stretched, linear condition in which it can be advanced through a catheter lumen to a selected vessel, and a relaxed, convoluted condition produced by a combination of a helical winding of the wire, and irregularities of the helical winding. When the wire is released from a catheter into a vessel, it assumes a randomly coiled, substantially space-filling mass which is lodged at the site of release. In a preferred embodiment, the helical winding in the wire's relaxed condition has about the same diameter as that of the vessel, and the wire, in its stretched condition, has a length of about 15-20 times the vessel diameter.

摘要翻译： 一种用于小血管血管闭塞的柔性优选盘绕线。 线材具有拉伸的线性状态，其中它可以通过导管内腔前进到选定的血管，以及通过线的螺旋绕组和螺旋形绕组的不规则性产生的松弛的卷曲状态。 当导线从导管释放到容器中时，它假定随机盘绕，基本上是空间填充的质量块，其被放置在释放位置。 在优选实施例中，线松弛条件下的螺旋绕组具有与容器相同的直径，并且在拉伸状态下，线的长度为容器直径的约15-20倍。