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公开(公告)号：US07320876B2
公开(公告)日：2008-01-22
申请号：US10284962
申请日：2002-10-31
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US20110318449A1
公开(公告)日：2011-12-29
申请号：US13154719
申请日：2011-06-07
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US20090074909A1
公开(公告)日：2009-03-19
申请号：US11963587
申请日：2007-12-21
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US08551724B2
公开(公告)日：2013-10-08
申请号：US13154719
申请日：2011-06-07
申请人： Douglas M. Webel , Donald E. Orr , Frank E. Ruch , Xingen Lei
发明人： Douglas M. Webel , Donald E. Orr , Frank E. Ruch , Xingen Lei
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US20110086127A1
公开(公告)日：2011-04-14
申请号：US12946821
申请日：2010-11-15
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US07833743B2
公开(公告)日：2010-11-16
申请号：US11963587
申请日：2007-12-21
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US07972805B2
公开(公告)日：2011-07-05
申请号：US12946821
申请日：2010-11-15
CPC分类号： C12Q1/48 , A23K20/189 , A23K20/26 , A23K50/00 , A23K50/75 , A23K50/80 , C12N9/16 , C12Y301/03008 , Y02A40/818
摘要： A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
摘要翻译： 描述了一种用于通过将食物与酵母中表达的植酸酶组合进料来提高包含肌醇六磷酸肌源的食品的营养价值的方法。 该方法包括将动物饲料与酵母中表达的植酸酶组合的步骤，其中植酸酶可以选自AppA1，AppA2和AppA的定点突变体。 本发明还能够减少饲料与体重增加比并增加动物的骨质量和矿物质含量。 还描述了包含AppA2或AppA的位点定向突变体的食品和饲料添加剂。
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公开(公告)号：US07084175B2
公开(公告)日：2006-08-01
申请号：US09870899
申请日：2001-05-31
IPC分类号： A61K31/20
CPC分类号： A23K50/00 , A23K10/22 , A23K20/158
摘要： The present invention is directed to compositions and methods for increasing the reproductive performance of breeding populations of swine. The swine feed compositions of the present invention are animal feed blends including marine animal products such as a fish oil or fish meal products. Methods include administering to the female swine a biologically effective amount of the swine feed composition comprising marine animal products wherein the marine animal products contain omega-3 fatty acids or esters thereof that serve as a source of metabolites in the female swine, to improve reproductive performance of the female swine.
摘要翻译： 本发明涉及用于增加猪繁殖种群繁殖性能的组合物和方法。 本发明的猪饲料组合物是动物饲料混合物，包括海产动物产品如鱼油或鱼粉制品。 方法包括向雌性猪施用生物有效量的包含海洋动物产品的猪饲料组合物，其中海洋动物产品含有ω-3脂肪酸或其酯作为雌性猪的代谢物来源，以改善生殖性能 的女猪。
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