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公开(公告)号:US20230182058A1
公开(公告)日:2023-06-15
申请号:US18165543
申请日:2023-02-07
Applicant: EMD Millipore Corporation
Inventor: Joseph Geringer , Robert Castro , Martin Szyk , Sophie Daudenarde , Joseph Almasian
CPC classification number: B01D46/4272 , B01D46/0004
Abstract: Port protection device particularly suited for an encapsulated filter unit. In certain embodiments, the protection device comprises a main body defining an internal region configured to receive a port or the like protruding from an encapsulated filter. In certain embodiments, the main body includes a slot that allows for easy removal of the protection device from the port or the like. A tube management system may be provided to receive and hold tubing. One suitable tube management system includes two spaced tangs that extend from the main body of the protection device and are configured to cooperatively receive and hold tubing between them.
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公开(公告)号:US11602709B2
公开(公告)日:2023-03-14
申请号:US16328640
申请日:2017-08-29
Applicant: EMD Millipore Corporation
Inventor: Joseph Geringer , Robert Castro , Martin Szyk , Sophie Daudenarde , Joseph Almasian
Abstract: Port protection device particularly suited for an encapsulated filter unit. In certain embodiments, the protection device comprises a main body defining an internal region configured to receive a port or the like protruding from an encapsulated filter. In certain embodiments, the main body includes a slot that allows for easy removal of the protection device from the port or the like. A tube management system may be provided to receive and hold tubing. One suitable tube management system includes two spaced tangs that extend from the main body of the protection device and are configured to cooperatively receive and hold tubing between them.
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公开(公告)号:US20180275012A1
公开(公告)日:2018-09-27
申请号:US15520082
申请日:2015-12-17
Applicant: EMD Millipore Corporation
Inventor: Stephen G. Hunt , Nicholas Landry , Martin Szyk
CPC classification number: G01M3/2876 , B01D61/243 , B01D65/022 , B01D65/104 , B01D2201/167 , B01D2273/18 , B01D2313/13 , B01D2313/16 , B01D2313/18 , B01D2313/58 , B01D2313/90 , F16J15/002 , F16K1/46
Abstract: The present disclosure relates to a filter capsule that supports direct integrity testing of an internal filter element. The filter capsule includes a filter housing having an inlet port, an outlet port, a passage running longitudinally between the inlet port and outlet port and holding a filter element, and an aseptic vent assembly. The filter housing also includes an integrity test assembly that can be used as a direct connection for integrity testing hardware, as opposed to upstream of the filter capsule. In one embodiment, the integrity test assembly comprises a body having a bore formed through its interior and a movable plunger within the bore. The plunger includes a handle to move the plunger between a closed position and an open position. Various seals between the plunger and the bore form a fluid tight seal between various portions of the plunger and the bore.
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公开(公告)号:US20180071687A1
公开(公告)日:2018-03-15
申请号:US15562110
申请日:2016-03-10
Applicant: EMD Millipore Corporation
Inventor: Joseph M. Almasian , Mark E. Chisholm , George A. Gagne, Jr. , Martin Szyk
CPC classification number: B01D63/082 , B01D63/14 , B01D69/10 , B01D2313/025 , B01D2313/04 , B01D2319/04 , C02F1/001 , C02F2103/003 , C02F2103/343 , C02F2201/002 , C02F2203/006 , C02F2301/04 , C02F2303/04
Abstract: A membrane-based separation device comprises multiple interconnected flat sheets of membrane bonded to a flexible film. The bonded films are bonded in a way to create an accordion or zig-zag shape. In certain embodiments, the first or upstream layer is affixed to a suitable housing, and the last or most downstream layer is also affixed to the suitable housing. The housing may contain an inlet port for the introduction of sample, and an outlet port for the removal of filtered sample. Flow through the segments is in parallel. Since the membranes are not folded or pleated, higher performance membranes (e.g., polysulfone based membranes with some degree of asymmetry) than those usable in pleated or folded systems can be used.
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公开(公告)号:US20130312492A1
公开(公告)日:2013-11-28
申请号:US13956428
申请日:2013-08-01
Applicant: EMD Millipore Corporation
Inventor: Brian Hillier , Martin Szyk , Aaron Burke , Joseph Almasian
IPC: G01N15/08
CPC classification number: F16K31/50 , F16K1/12 , F16K11/22 , F16K31/445 , F16K31/60 , G01N15/0826 , Y10T137/0318 , Y10T137/7932 , Y10T137/794 , Y10T137/85938 , Y10T137/87885
Abstract: Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.
Abstract translation: 流体输送装置包括具有通过其内部的至少一部分形成的孔的主体。 包含在孔内的是可移动的柱塞,其移动而不改变主体的轴向尺寸。 身体的第一端包含设计成连接到上游部件的面。 主体的第二端连接到诸如过滤器,管道等的下游部件。当处于关闭位置时,柱塞的第一端与主体的表面对准,其结合形成一个 可蒸发的表面和抵抗环境的无菌屏障到身体内部的其余部分,柱塞和下游部件。 外环形套环可相对于主体旋转并使柱塞在孔内轴向移动,从开放到闭合位置。
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公开(公告)号:US20130306897A1
公开(公告)日:2013-11-21
申请号:US13955309
申请日:2013-07-31
Applicant: EMD Millipore Corporation
Inventor: Brian Hillier , Martin Szyk , Aaron Burke , Joseph Almasian
CPC classification number: F16K31/50 , F16K1/12 , F16K11/22 , F16K31/445 , F16K31/60 , G01N15/0826 , Y10T137/0318 , Y10T137/7932 , Y10T137/794 , Y10T137/85938 , Y10T137/87885
Abstract: Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.
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公开(公告)号:US12090436B2
公开(公告)日:2024-09-17
申请号:US18165543
申请日:2023-02-07
Applicant: EMD Millipore Corporation
Inventor: Joseph Geringer , Robert Castro , Martin Szyk , Sophie Daudenarde , Joseph Almasian
CPC classification number: B01D46/4272 , B01D46/0004
Abstract: Port protection device particularly suited for an encapsulated filter unit. In certain embodiments, the protection device comprises a main body defining an internal region configured to receive a port or the like protruding from an encapsulated filter. In certain embodiments, the main body includes a slot that allows for easy removal of the protection device from the port or the like. A tube management system may be provided to receive and hold tubing. One suitable tube management system includes two spaced tangs that extend from the main body of the protection device and are configured to cooperatively receive and hold tubing between them.
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公开(公告)号:US10656046B2
公开(公告)日:2020-05-19
申请号:US15520082
申请日:2015-12-17
Applicant: EMD Millipore Corporation
Inventor: Stephen G. Hunt , Nicholas Landry , Martin Szyk
Abstract: The present disclosure relates to a filter capsule that supports direct integrity testing of an internal filter element. The filter capsule includes a filter housing having an inlet port, an outlet port, a passage running longitudinally between the inlet port and outlet port and holding a filter element, and an aseptic vent assembly. The filter housing also includes an integrity test assembly that can be used as a direct connection for integrity testing hardware, as opposed to upstream of the filter capsule. In one embodiment, the integrity test assembly comprises a body having a bore formed through its interior and a movable plunger within the bore. The plunger includes a handle to move the plunger between a closed position and an open position. Various seals between the plunger and the bore form a fluid tight seal between various portions of the plunger and the bore.
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公开(公告)号:US08915264B2
公开(公告)日:2014-12-23
申请号:US13955309
申请日:2013-07-31
Applicant: EMD Millipore Corporation
Inventor: Brian Hillier , Martin Szyk , Aaron Burke , Joseph Almasian
CPC classification number: F16K31/50 , F16K1/12 , F16K11/22 , F16K31/445 , F16K31/60 , G01N15/0826 , Y10T137/0318 , Y10T137/7932 , Y10T137/794 , Y10T137/85938 , Y10T137/87885
Abstract: Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.
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公开(公告)号:US20140339146A1
公开(公告)日:2014-11-20
申请号:US14451524
申请日:2014-08-05
Applicant: EMD Millipore Corporation
Inventor: Joseph Almasian , Jeremy Perreault , Martin Szyk
CPC classification number: B01D35/306 , B01D27/00 , B01D27/08 , B01D29/15 , B01D35/30 , B01D2201/291 , B01D2201/302 , B01D2201/4046 , B01D2201/4084 , B01D2313/02 , B01D2313/44
Abstract: A removable device that ensures that the port of a filter cartridge is liquid tightly sealed to the port of the head of a housing even when there is insufficient room beneath the bowl to allow one to physically secure the cartridge port to the head port before securing the head and bowl together. The invention uses one or more removably attached alignment devices to center the cartridge in the bowl and maintain it at a height sufficient to ensure that the two ports are aligned and liquid tightly sealed to each other when the bowl and head are mated together.
Abstract translation: 一种可移除的装置,其确保过滤器滤芯的端口液密地密封到壳体的头部的端口,即使在碗下方没有足够的空间以允许在固定之前物理地将盒式端口固定到头端口 头和碗在一起。 本发明使用一个或多个可移除地附接的对准装置将筒定位在碗中,并将其保持在足够高的高度,以确保当碗和头配合在一起时两个端口对准并且彼此液密地密封。
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