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公开(公告)号：US20210361421A1
公开(公告)日：2021-11-25
申请号：US17393624
申请日：2021-08-04
发明人： Ankita Bordoloi Gurunath , Hao Shang , Jingjia Han
摘要： Devices and methods for reinforcing a regenerative heart valve are provided. A reinforcing element can provide structure and rigidity to withstand stresses that occur within the aortic root. In some instances, a support ring is attached to a regenerative heart valve. In some instances, a tubular wall is provided surrounding a regenerative heart valve.
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公开(公告)号：US20220296775A1
公开(公告)日：2022-09-22
申请号：US17806430
申请日：2022-06-10
发明人： Manouchehr A. Miraki , Jingjia Han , Bin Tian , Angela B. De La Fuente , Liqiong Gui , Hao Shang , Lien Huong Thi Hoang , Vicky Hong Do
摘要： An annuloplasty ring prosthesis comprising a frame having an outer surface; and a cover surrounding the frame. The cover comprises a bioprosthetic tissue that can be regenerative or fixed and non-regenerative. The frame can be bioabsorbable or non-degradable. A ring prosthesis and a method of manufacturing a ring prosthesis is also provided. The ring prosthesis comprising an elongated rod member formed into a substantially ring shape, the elongated rod member being formed substantially from a flat bioprosthetic tissue.
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公开(公告)号：US20240148506A1
公开(公告)日：2024-05-09
申请号：US18417168
申请日：2024-01-19
发明人： Jingjia Han , Ling Zhou , Holly Kung Jung Hsu
CPC分类号： A61F2/2457 , A61L27/16 , A61L27/28 , A61L27/3625 , A61L27/3633 , A61L27/54 , A61L27/58 , A61F2002/0081 , A61F2210/0004 , A61F2210/0076 , A61F2220/0075 , A61L2300/412
摘要： An artificial chordae system can comprise a surgical pad configured to be externally positioned over an opening formed in a portion of a heart wall adjacent to a heart ventricle, and a tether comprising a cord and a tissue ingrowth promoting coating over at least a portion of the cord, the tether comprising a distal portion being configured to couple a heart valve leaflet and a proximal portion being coupled to the surgical pad. The tether can be dimensioned to extend from the heart valve leaflet through the heart ventricle to the opening in the heart wall, and through the opening in the heart wall to the surgical pad. The tissue ingrowth promoting coating can comprise a protein and be configured to promote native tissue growth over the cord to provide regenerated native tissue over the tether for coupling the heart valve leaflet to the heart wall.
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公开(公告)号：US20230056175A1
公开(公告)日：2023-02-23
申请号：US18047983
申请日：2022-10-19
发明人： Jingjia Han , Austin Engelbrecht , Yin Fang , Hui-Chi Yang , Felino V. Cortez, JR. , Megan Cortez , Luke Anthony Zanetti
IPC分类号： A61B17/04
摘要： A surgical pad can comprise a flexible pad portion configured to be positioned over an opening in a target tissue. A plurality of elongate ribs can be distributed across a surface of the flexible pad portion oriented away from the target tissue and can be coupled to the flexible pad portion. A surgical pad can comprise a central opening configured to be aligned with an opening in a target tissue, and a plurality of edge openings distributed around an outer edge portion. A method can comprise positioning a spacer between a target tissue and a surgical pad to adjust the tension of surgical cords secured to surgical pad. A method can comprise positioning a spacer between a surface of a surgical pad oriented away from a target tissue and portions of surgical cords secured over the surface of the surgical pad, to adjust the tension of the surgical cords.
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公开(公告)号：US20230158204A1
公开(公告)日：2023-05-25
申请号：US18157371
申请日：2023-01-20
CPC分类号： A61L27/34 , A61L27/50 , C09D5/1637
摘要： An anti-fouling implantable material and a method of making the anti-fouling implantable material are disclosed. The anti-fouling implantable material includes a polymeric reinforcement layer, an intermediate layer comprising a protective polymer membrane, and an outer layer comprising an ionic polymer. The anti-fouling implantable material may have chemical and/or physical properties compatible with body tissue properties. The anti-fouling implantable material may be used for implantable medical devices, such as prosthetic heart valves and vascular grafts, among others.
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公开(公告)号：US20220296779A1
公开(公告)日：2022-09-22
申请号：US17806041
申请日：2022-06-08
发明人： Bin Tian , Angela B. De La Fuente , Gregory A. Wright , Jingjia Han , Hao Shang
IPC分类号： A61L27/36
摘要： Methods for preparing bioprosthetic tissue are provided. In some instances, bioprosthetic tissue is treated to remove antigenic biomolecules. In some instances, prepared bioprosthetic tissues are incorporated into a medical device.
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公开(公告)号：US20220154370A1
公开(公告)日：2022-05-19
申请号：US17649304
申请日：2022-01-28
发明人： Jingjia Han , Hao Shang
摘要： A method of applying fibrous material to a medical device component involves coupling a medical device component a holder device, rotating a reservoir device containing a liquid polymeric solution to expel at least a portion of the liquid polymeric solution from an orifice of the reservoir device, the expelled at least a portion of the liquid polymeric solution forming one or more strands of fibrous material in a deposition plane, and rotating the holder device at least partially within the deposition plane to apply at least a first portion of the one or more strands of fibrous material to one or more surfaces of the medical device component, thereby forming a fibrous covering on the one or more surfaces of the medical device component.
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