Deposition method for endoprostheses provided for constantly administering medicaments
    4.
    发明申请
    Deposition method for endoprostheses provided for constantly administering medicaments 审中-公开
    提供用于不断施用药物的内用假体的沉积方法

    公开(公告)号:US20050163914A1

    公开(公告)日:2005-07-28

    申请号:US10507924

    申请日:2003-03-17

    摘要: The present invention describes a deposition method for applying an active ingredient onto an endoprosthesis with a thin polymer coating. By means of the inventive deposition method which can be carried out in a technically easy way it is possible to bring about a slow and largely constant active ingredient release, as shown in III. 1 using tretinoin as the example. Since further processing steps are not necessary after the application of the active ingredient(s), no destruction of the active ingredient by the application of a second polymer coating, for example, has to be feared. Thus, relatively unstable active ingredients, such as tretinoin, can also be applied onto the endoprosthesis without any problems.

    摘要翻译: 本发明描述了一种使用薄聚合物涂层将活性成分施用到内用假体上的沉积方法。 通过本发明的沉积方法,其可以以技术上容易的方式进行,如III所示,可以产生缓慢且大部分恒定的活性成分释放。 1以维甲酸为例。 由于在施用活性成分之后不需要进一步的加工步骤,所以不必担心例如通过施加第二聚合物涂层破坏活性成分。 因此,相对不稳定的活性成分(如维甲酸)也可以应用于内用假体,没有任何问题。