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公开(公告)号：US20250114242A1
公开(公告)日：2025-04-10
申请号：US18741632
申请日：2024-06-12
Applicant: ForSight Vision5, Inc.
Inventor： Eugene de Juan, JR. , Yair Alster , Cary J. Reich , K. Angela Macfarlane , Janelle Chang , Stephen Boyd , David Sierra , Jose D. Alejandro , Douglas Sutton , Alexander J. Gould
Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
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公开(公告)号：US20190105198A1
公开(公告)日：2019-04-11
申请号：US16003857
申请日：2018-06-08
Applicant: ForSight Vision5, Inc.
Inventor： Yair Alster , Eugene de Juan, JR. , Cary J. Reich , Stephen Boyd , David Sierra , Jose D. Alejandro , K. Angela Macfarlane , Douglas Sutton
IPC: A61F9/00 , A61K31/55 , A61K31/5377 , A61K31/5575 , A61K31/407 , A61K31/58 , A61K38/00 , A61K31/5415 , A61K31/43 , A61K31/19 , A61K31/557 , A61K31/4178 , A61K31/7036 , A61K31/573 , A61K31/568 , A61K9/00 , A61M31/00 , A61K31/335 , A61K31/56
Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
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公开(公告)号：US20160243291A1
公开(公告)日：2016-08-25
申请号：US15027573
申请日：2014-10-13
Applicant: FORSIGHT VISION5, INC.
Inventor： Cary J. Reich , K. Angela Macfarlane , Yair Alster , Logan Stark
CPC classification number: A61L31/125 , A61F9/0017 , A61K9/0051 , A61L31/16 , A61L2430/16
Abstract: The present disclosure is directed to a pharmaceutical delivery device useful for the treatment of ocular diseases and disorders through sustained release of therapeutic doses of a pharmaceutical agent, while increasing or reducing formation and/or accumulation of mucus.
Abstract translation: 本公开涉及用于通过持续释放治疗剂量的药剂来治疗眼部疾病和病症的药物递送装置，同时增加或减少粘液的形成和/或积聚。
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公开(公告)号：US20140121612A1
公开(公告)日：2014-05-01
申请号：US14063571
申请日：2013-10-25
Applicant: ForSight Vision5, Inc.
Inventor： Anne Brody Rubin , Yair Alster , Cary J. Reich
IPC: A61F9/00
CPC classification number: A61F9/0017 , A61F2250/0067 , Y10T156/1036
Abstract: Disclosed is an ocular device including a first structure formed of a first material providing a first shape to the ocular device prior to positioning the ocular device on the surface of the eye, a second structure formed of a second, different material having a tubular structure and a lumen through which the first structure extends, and at least one therapeutic agent is dispersed within the second material of the second structure. The first shape of the ocular device conforms to a second, different shape after positioning the ocular device on the surface of the eye. Upon being removed from the eye, the ocular device retains the second shape or changes to a third shape different from both the first shape and the second shape. Related apparatus, systems and method are described.
Abstract translation: 公开了一种眼部装置，其包括第一结构，该第一结构由在将眼睛装置定位在眼睛的表面上之前向眼睛装置提供第一形状的第一材料形成，第二结构由具有管状结构的第二不同材料形成， 第一结构延伸穿过的内腔，以及至少一种治疗剂分散在第二结构的第二材料内。 眼睛装置的第一种形状在将眼睛装置定位在眼睛的表面上之后符合第二种不同的形状。 当从眼睛移除时，眼睛装置保持第二形状或改变为不同于第一形状和第二形状的第三形状。 描述相关装置，系统和方法。
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公开(公告)号：US20230102547A1
公开(公告)日：2023-03-30
申请号：US17739037
申请日：2022-05-06
Applicant: ForSight Vision5, Inc.
Inventor： Yair Alster , Eugene de Juan, JR. , Cary J. Reich , Stephen Boyd , David Sierra , Jose D. Alejandro , K. Angela Macfarlane , Douglas Sutton
IPC: A61F9/00 , A61K9/00 , A61K31/19 , A61K31/407 , A61K31/4178 , A61K31/5377 , A61K31/5415 , A61K31/43 , A61K31/55 , A61K31/557 , A61K31/5575 , A61K31/56 , A61K31/568 , A61K31/573 , A61K31/58 , A61K31/7036 , A61K38/00 , A61M31/00 , A61K31/335
Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
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Patent Agency Ranking
公开(公告)号：US20220331335A1
公开(公告)日：2022-10-20
申请号：US17535000
申请日：2021-11-24
Applicant: ForSight Vision5, Inc.
Inventor： Cary J. Reich , Carlos Schuler , Qiang Ye , Logan Stark , Rachna Jain
Abstract: The present invention is directed to compositions of bimatoprost, processes of preparing these compositions, devices comprising these compositions, and methods of lowering intraocular pressure.
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公开(公告)号：US20200222235A1
公开(公告)日：2020-07-16
申请号：US16580529
申请日：2019-09-24
Applicant: ForSight Vision5, Inc.
Inventor： Anne Brody Rubin , Yair Alster , Cary J. Reich
IPC: A61F9/00
Abstract: Disclosed is an ocular device including a first structure formed of a first material providing a first shape to the ocular device prior to positioning the ocular device on the surface of the eye, a second structure formed of a second, different material having a tubular structure and a lumen through which the first structure extends, and at least one therapeutic agent is dispersed within the second material of the second structure. The first shape of the ocular device conforms to a second, different shape after positioning the ocular device on the surface of the eye. Upon being removed from the eye, the ocular device retains the second shape or changes to a third shape different from both the first shape and the second shape. Related apparatus, systems and method are described.
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公开(公告)号：US20180177634A1
公开(公告)日：2018-06-28
申请号：US15905525
申请日：2018-02-26
Applicant: ForSight Vision5, Inc.
Inventor： Eugene de Juan, JR. , Yair Alster , Cary J. Reich , K. Angela Macfarlane , Janelle Chang , Stephen Boyd , David Sierra , Jose D. Alejandro , Douglas Sutton , Alexander J. Gould
CPC classification number: A61F9/0017 , A61B17/00234 , A61K9/0051 , A61K47/34 , A61L27/025 , A61L27/16
Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
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公开(公告)号：US09937073B2
公开(公告)日：2018-04-10
申请号：US14600505
申请日：2015-01-20
Applicant: ForSight Vision5, Inc.
Inventor： Eugene de Juan, Jr. , Yair Alster , Cary J. Reich , K. Angela Macfarlane , Janelle Chang , Stephen Boyd , David Sierra , Jose D. Alejandro , Douglas Sutton , Alexander J. Gould
CPC classification number: A61F9/0017 , A61B17/00234 , A61K9/0051 , A61K47/34 , A61L27/025 , A61L27/16
Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
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公开(公告)号：US20210128351A1
公开(公告)日：2021-05-06
申请号：US16930678
申请日：2020-07-16
Applicant: ForSight Vision5, Inc.
Inventor： Yair Alster , Eugene de Juan, JR. , Cary J. Reich , Stephen Boyd , David Sierra , Jose D. Alejandro , K. Angela Macfarlane , Douglas Sutton
IPC: A61F9/00 , A61K9/00 , A61K31/19 , A61K31/407 , A61K31/4178 , A61K31/5377 , A61K31/5415 , A61K31/43 , A61K31/55 , A61K31/557 , A61K31/5575 , A61K31/56 , A61K31/568 , A61K31/573 , A61K31/58 , A61K31/7036 , A61K38/00 , A61M31/00 , A61K31/335
Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
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