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公开(公告)号：US10436858B2
公开(公告)日：2019-10-08
申请号：US15532680
申请日：2015-12-02
Applicant: General Electric Company
Inventor： Dattesh Dayanand Shanbhag , Rakesh Mullick , Sheshadri Thiruvenkadam , Florian Wiesinger , Sudhanya Chatterjee , Kevin Matthew Koch
Abstract: An imaging system and method are disclosed. An MR image and measured B0 field map of a target volume in a subject are reconstructed, where the MR image includes one or more bright and/or dark regions. One or more distinctive constituent materials corresponding to the bright regions are identified. Each dark region is iteratively labeled as one or more ambiguous constituent materials. Susceptibility values corresponding to each distinctive and iteratively labeled ambiguous constituent material is assigned. A simulated B0 field map is iteratively generated based on the assigned susceptibility values. A similarity metric is determined between the measured and simulated B0 field maps. Constituent materials are identified in the dark regions based on the similarity metric to ascertain corresponding susceptibility values. The MRI data is corrected based on the assigned and ascertained susceptibility values. A diagnostic assessment of the target volume is determined based on the corrected MRI data.
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2.发明申请SYSTEM AND METHOD FOR JOINT ESTIMATION OF ATTENUATION AND ACTIVITY INFORMATION 有权用于联合评估衰减和活动信息的系统和方法公开(公告)号：US20160174919A1
公开(公告)日：2016-06-23
申请号：US14579039
申请日：2014-12-22
Applicant: General Electric Company
Inventor： Sangtae Ahn , Ravindra Mohan Manjeshwar , Florian Wiesinger , Dattesh Dayanand Shanbhag , Sandeep Suryanarayana Kaushik , Hua Qian , Anne Menini
IPC: A61B6/00 , G01T1/24 , G06T7/00 , A61B8/00 , A61B6/03 , A61B5/055 , A61B5/00 , A61B5/053 , G01R33/56 , G06T11/00
CPC classification number: A61B6/4417 , A61B5/0059 , A61B5/0536 , A61B5/055 , A61B6/032 , A61B6/037 , A61B6/5205 , A61B6/5258 , A61B8/4416 , G01R33/481 , G01R33/56 , G01T1/1603 , G01T1/1647 , G01T1/249 , G06T7/0012 , G06T11/003 , G06T11/006 , G06T2200/04 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/30024 , G06T2207/30061 , G06T2211/40 , G06T2211/424
Abstract: Imaging system and method are presented. Emission scan (ES) and anatomical scan (AS) data corresponding to a target volume in a subject are received. One or more at least partial AS images are reconstructed using AS data. An image-space certainty (IC) map representing a confidence level (CL) for attenuation coefficients of selected voxels in AS images and a preliminary attenuation (PA) map based on AS images are generated. One or more of selected attenuation factors (AF) in projection-space are initialized based on PA map. A projection-space certainty (PC) map representing CL for the selected AF is generated based on IC map. An emission image of the target volume is initialized. The selected AF and emission image are iteratively updated based on the ES data, PC map, initial AF, and/or initial emission image. A desired emission image and/or AF values are determined based on the iteratively updated AF and/or emission image.
Abstract translation: 介绍了成像系统和方法。 接收与对象中的目标体积对应的发射扫描（ES）和解剖扫描（AS）数据。 使用AS数据重构一个或多个至少部分AS图像。 生成表示AS图像中的选定体素的衰减系数的置信水平（CL）和基于AS图像的初步衰减（PA）图的图像空间确定性（IC）图。 基于PA映射初始化投影空间中的一个或多个选择的衰减因子（AF）。 基于IC映射生成表示所选AF的CL的投影空间确定性（PC）映射。 初始化目标体积的发射图像。 基于ES数据，PC映射，初始AF和/或初始发射图像迭代地更新所选择的AF和发射图像。 基于迭代更新的AF和/或发射图像来确定期望的发射图像和/或AF值。
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公开(公告)号：US10362992B2
公开(公告)日：2019-07-30
申请号：US15101538
申请日：2014-09-05
Applicant: General Electric Company
Inventor： Kumar Rajamani , Sandeep Narendra Gupta , Rakesh Mullick , Dattesh Dayanand Shanbhag
IPC: A61B5/055 , A61B5/00 , A61B6/00 , A61B8/08 , G01R33/565 , A61B5/11 , A61B6/03 , G01R33/56 , G01R33/563
Abstract: A system and method for detecting motion is presented. The system and method includes identifying a region of interest in the plurality of images corresponding to a subject of interest. Furthermore, the system and method includes determining signal characteristics corresponding to the region of interest. In addition, the system and method includes generating a composite signal, where the composite signal comprises an aggregate of the signal characteristics corresponding to the region of interest. The system and method also includes analyzing the composite signal to detect motion in the region of interest.
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公开(公告)号：US20190005640A1
公开(公告)日：2019-01-03
申请号：US15640909
申请日：2017-07-03
Applicant: General Electric Company
Inventor： Dattesh Dayanand Shanbhag , Mirabela Rusu , Sandeep Narendra Gupta
Abstract: The disclosed approach employs a generic methodology for transforming individual modality specific multi-parametric data into data, e.g., maps or images, which provides direct insight into the underlying physiology of the tissue. This may facilitate better clinical evaluation of the disease data as well as help non-imaging technologists and scientist to directly correlate imaging findings with basic biological phenomenon being studied with imaging.
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5.发明授权公开(公告)号：US09474495B2
公开(公告)日：2016-10-25
申请号：US14579039
申请日：2014-12-22
Applicant: General Electric Company
Inventor： Sangtae Ahn , Ravindra Mohan Manjeshwar , Florian Wiesinger , Dattesh Dayanand Shanbhag , Sandeep Suryanarayana Kaushik , Hua Qian , Anne Menini
IPC: A61B6/00 , G06T7/00 , G01R33/56 , G01T1/24 , G06T11/00 , A61B6/03 , A61B5/055 , A61B5/00 , A61B5/053 , A61B8/00
CPC classification number: A61B6/4417 , A61B5/0059 , A61B5/0536 , A61B5/055 , A61B6/032 , A61B6/037 , A61B6/5205 , A61B6/5258 , A61B8/4416 , G01R33/481 , G01R33/56 , G01T1/1603 , G01T1/1647 , G01T1/249 , G06T7/0012 , G06T11/003 , G06T11/006 , G06T2200/04 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/30024 , G06T2207/30061 , G06T2211/40 , G06T2211/424
Abstract: Imaging system and method are presented. Emission scan (ES) and anatomical scan (AS) data corresponding to a target volume in a subject are received. One or more at least partial AS images are reconstructed using AS data. An image-space certainty (IC) map representing a confidence level (CL) for attenuation coefficients of selected voxels in AS images and a preliminary attenuation (PA) map based on AS images are generated. One or more of selected attenuation factors (AF) in projection-space are initialized based on PA map. A projection-space certainty (PC) map representing CL for the selected AF is generated based on IC map. An emission image of the target volume is initialized. The selected AF and emission image are iteratively updated based on the ES data, PC map, initial AF, and/or initial emission image. A desired emission image and/or AF values are determined based on the iteratively updated AF and/or emission image.
Abstract translation: 介绍了成像系统和方法。 接收与对象中的目标体积对应的发射扫描（ES）和解剖扫描（AS）数据。 使用AS数据重构一个或多个至少部分AS图像。 生成表示AS图像中的选定体素的衰减系数的置信水平（CL）和基于AS图像的初步衰减（PA）图的图像空间确定性（IC）图。 基于PA映射初始化投影空间中的一个或多个选择的衰减因子（AF）。 基于IC映射生成表示所选AF的CL的投影空间确定性（PC）映射。 初始化目标体积的发射图像。 基于ES数据，PC映射，初始AF和/或初始发射图像迭代地更新所选择的AF和发射图像。 基于迭代更新的AF和/或发射图像来确定期望的发射图像和/或AF值。
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Patent Agency Ranking
6.发明申请公开(公告)号：US20160310082A1
公开(公告)日：2016-10-27
申请号：US15101538
申请日：2014-09-05
Applicant: General Electric Company
Inventor： Kumar Rajamani , Sandeep Narendra Gupta , Rakesh Mullick , Dattesh Dayanand Shanbhag
IPC: A61B5/00 , A61B6/03 , A61B5/02 , A61B6/00 , G06T7/20 , A61B8/00 , G01R33/56 , G01R33/565 , G01R33/48 , G06T7/00 , A61B5/055 , A61B8/08
CPC classification number: A61B5/7207 , A61B5/0044 , A61B5/055 , A61B5/1128 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/5264 , A61B8/5276 , A61B2576/00 , G01R33/5601 , G01R33/5608 , G01R33/56308 , G01R33/56509
Abstract: A system and method for detecting motion is presented. The system and method includes identifying a region of interest in the plurality of images corresponding to a subject of interest. Furthermore, the system and method includes determining signal characteristics corresponding to the region of interest. In addition, the system and method includes generating a composite signal, where the composite signal comprises an aggregate of the signal characteristics corresponding to the region of interest. The system and method also includes analyzing the composite signal to detect motion in the region of interest.
Abstract translation: 提出了一种用于检测运动的系统和方法。 该系统和方法包括识别与感兴趣对象相对应的多个图像中的感兴趣区域。 此外，该系统和方法包括确定对应于感兴趣区域的信号特性。 此外，该系统和方法包括生成复合信号，其中复合信号包括对应于感兴趣区域的信号特征的聚合。 该系统和方法还包括分析复合信号以检测感兴趣区域中的运动。
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公开(公告)号：US20140148684A1
公开(公告)日：2014-05-29
申请号：US13686226
申请日：2012-11-27
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Thomas Kwok-Fah Foo , Christopher Judson Hardy , Charles William Stearns , Ravindra Mohan Manjeshwar , Florian Wiesinger , Dattesh Dayanand Shanbhag
CPC classification number: A61B6/5247 , A61B5/0035 , A61B5/0037 , A61B5/055 , A61B5/0555 , A61B5/7289 , A61B5/7292 , A61B6/02 , A61B6/037 , A61B6/04 , A61B6/0407 , A61B6/4417 , A61B6/461 , A61B6/469 , A61B6/488 , A61B6/541 , A61B6/542 , A61B6/545 , A61B6/548
Abstract: Exemplary embodiments of the present disclosure are directed to scheduling positron emission tomography (PET) scans for a combined PET-MRI scanner based on an acquisition of MR scout images of a subject. An anatomy and orientation of the subject can be determined based on the MR scout images and the schedule for acquiring PET scans of the subject can be determined from the anatomy of the subject. The schedule generated using exemplary embodiments of the present disclosure can specify a sequence of bed positions, scan durations at each bed position, and whether respiratory gating will be used at one or more of the bed positions.
Abstract translation: 本公开的示例性实施例涉及基于对受试者的MR侦察图像的获取来调度用于组合的PET-MRI扫描仪的正电子发射断层摄影（PET）扫描。 可以基于MR侦察图像来确定被摄体的解剖结构和取向，并且可以从对象的解剖结构确定用于获取对象的PET扫描的时间表。 使用本公开的示例性实施例产生的日程表可以指定床位置的顺序，每个床位置的扫描持续时间，以及是否在一个或多个床位置使用呼吸门控。
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公开(公告)号：US20180032681A1
公开(公告)日：2018-02-01
申请号：US15224364
申请日：2016-07-29
Applicant: General Electric Company
Inventor： Chandan Kumar Mallappa Aladahalli , Dattesh Dayanand Shanbhag , Rakesh Mullick , Venkata Veerendra Nadh Chebrolu , Ersin Bayram
IPC: G06F19/00 , G06F3/0484 , G06F3/0482
Abstract: The present disclosure relates to a method for assessing biological features, the method that includes rendering a graphical user interface allowing a user to select patient cohort information defining one or more characteristics of a patient cohort and allowing a user to select an analysis technique from a plurality of analysis techniques, wherein the analysis technique operates on the patient data from both the first data acquisition modality and the second data acquisition modality to generate a derived variable. The method also includes allowing a user to define a threshold for the derived variable to define a first patient group above the threshold and a second patient group below the threshold for each patient of a patient cohort.
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公开(公告)号：US20170371010A1
公开(公告)日：2017-12-28
申请号：US15532680
申请日：2015-12-02
Applicant: General Electric Company
Inventor： Dattesh Dayanand Shanbhag , Rakesh Mullick , Sheshadri Thiruvenkadam , Florian Wiesinger , Sudhanya Chatterjee , Kevin Matthew Koch
CPC classification number: G01R33/243 , A61B5/0035 , A61B5/055 , G01R33/481 , G01R33/4816 , G01R33/5608 , G01R33/56536
Abstract: An imaging system and method are disclosed. An MR image and measured B0 field map of a target volume in a subject are reconstructed, where the MR image includes one or more bright and/or dark regions. One or more distinctive constituent materials corresponding to the bright regions are identified. Each dark region is iteratively labeled as one or more ambiguous constituent materials. Susceptibility values corresponding to each distinctive and iteratively labeled ambiguous constituent material is assigned. A simulated B0 field map is iteratively generated based on the assigned susceptibility values. A similarity metric is determined between the measured and simulated B0 field maps. Constituent materials are identified in the dark regions based on the similarity metric to ascertain corresponding susceptibility values. The MRI data is corrected based on the assigned and ascertained susceptibility values. A diagnostic assessment of the target volume is determined based on the corrected MRI data.
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公开(公告)号：US09594139B2
公开(公告)日：2017-03-14
申请号：US14229464
申请日：2014-03-28
Applicant: General Electric Company
Inventor： Florian Wiesinger , Dattesh Dayanand Shanbhag , Laura Irene Sacolick , Sandeep Suryanarayana Kaushik
CPC classification number: G01R33/5608 , G01R33/4816 , G01R33/4824
Abstract: Systems and methods of classifying component tissues of magnetic resonance images, where the method includes performing a proton density weighted, short echo-time magnetic resonance imaging measurement over a first volume field-of-view region of interest (ROI), repeating a series refining the first volume field-of-view ROI into a plurality of subsequent smaller ROI volumes having respective smaller resolutions, reconstructing a complex image from the plurality of magnetic resonance imaging measurements, performing a bias correction on at least one of the plurality of subsequent smaller ROI volumes, and classifying the ROI volumes by tissue type based on the bias-corrected image signal, wherein at least one tissue type is bone. A non-transitory medium containing processor instructions and a system are disclosed.
Abstract translation: 分类磁共振图像的组分组织的系统和方法，其中该方法包括在第一体积视野区域（ROI）上执行质子密度加权的短回波 - 时间磁共振成像测量，重复串联精炼 将第一体积视野ROI转换成具有各自较小分辨率的多个随后较小的ROI卷，从所述多个磁共振成像测量中重建复数图像，对所述多个随后的较小ROI中的至少一个执行偏置校正 体积，并且基于偏差校正图像信号通过组织类型对ROI体积进行分类，其中至少一种组织类型是骨骼。 公开了一种包含处理器指令和系统的非暂时介质。
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