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1.
公开(公告)号:US20230242530A1
公开(公告)日:2023-08-03
申请号:US18297546
申请日:2023-04-07
Applicant: Genentech, Inc.
Inventor: Simon Charles GOODACRE , Mark ZAK , F. Anthony ROMERO , Yun-Xing CHENG , Limin CHENG , Rongbao HUA
IPC: C07D471/04 , A61P11/06 , C07D519/00
CPC classification number: C07D471/04 , A61P11/06 , C07D519/00
Abstract: Compounds of Formula (I) and (II), or a stereoisomer, tautomer, solvate, prodrug or salt thereof, and methods of use as Janus kinase inhibitors are described herein.
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公开(公告)号:US20220281893A1
公开(公告)日:2022-09-08
申请号:US17666350
申请日:2022-02-07
Applicant: Genentech, Inc.
Inventor: Lewis J. GAZZARD , Samantha Alyson GREEN , Matthew Leo LANDRY , Sushant MALHOTRA , Michael SIU , Steven DO , Yun-Xing CHENG , Limin CHENG , Jianfeng XIN , Mingtao HE
IPC: C07D498/22 , C07D519/00 , A61K31/553 , A61K45/06 , A61P35/00
Abstract: Provided herein are tetracyclic oxazepinyl compounds useful in the treatment on cancers.
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3.
公开(公告)号:US20190202822A1
公开(公告)日:2019-07-04
申请号:US16293129
申请日:2019-03-05
Applicant: Genentech, Inc.
Inventor: Simon Charles GOODACRE , Mark ZAK , F. Anthony ROMERO , Yun-Xing CHENG , Limin CHENG , Rongbao HUA
IPC: C07D471/04 , C07D519/00 , A61P11/06
CPC classification number: C07D471/04 , A61P11/06 , C07D519/00
Abstract: Compounds of Formula (I) and (II), or a stereoisomer, tautomer, solvate, prodrug or salt thereof, and methods of use as Janus kinase inhibitors are described herein.
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公开(公告)号:US20240383915A1
公开(公告)日:2024-11-21
申请号:US18554438
申请日:2022-04-06
Applicant: Genentech, Inc.
Inventor: Lewis J. GAZZARD , Samantha Alyson GREEN , Elizabeth H. KELLEY , Matthew Leo LANDRY , Sushant MALHOTRA , Benjamin David RAVETZ , Michael SIU , Jack Alexander TERRETT , BinQing WEI , Steven DO , Yun-Xing CHENG , Limin CHENG , Jianfeng XIN , Mingtao HE , Guosheng WU , Yinlei SUN , Cheng SHAO , Aijun LU , Yulai ZHANG
IPC: C07D498/04 , A61K31/553 , A61K45/06 , C07D519/00
Abstract: Provided herein are acyclic oxazepinyl compounds useful in the treatment on cancers.
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5.
公开(公告)号:US20200270248A1
公开(公告)日:2020-08-27
申请号:US16870602
申请日:2020-05-08
Applicant: Genentech, Inc.
Inventor: Simon Charles GOODACRE , Mark ZAK , F. Anthony ROMERO , Yun-Xing CHENG , Limin CHENG , Rongbao HUA
IPC: C07D471/04 , A61P11/06 , C07D519/00
Abstract: Compounds of Formula (I) and (II), or a stereoisomer, tautomer, solvate, prodrug or salt thereof, and methods of use as Janus kinase inhibitors are described herein.
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