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公开(公告)号:US20060009416A1
公开(公告)日:2006-01-12
申请号:US11226615
申请日:2005-09-13
申请人: Georg Wondrak , Michael Roberts , Moonsun Kim , Myron Jacobson , Elaine Jacobson
发明人: Georg Wondrak , Michael Roberts , Moonsun Kim , Myron Jacobson , Elaine Jacobson
IPC分类号: A61K31/7076
CPC分类号: A61Q19/004 , A61K8/4913 , A61K8/4926 , A61K31/401 , A61K31/44 , A61K2800/57 , A61Q17/04 , A61Q19/00
摘要: The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.
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公开(公告)号:US20050042188A1
公开(公告)日:2005-02-24
申请号:US10937537
申请日:2004-09-09
申请人: Georg Wondrak , Michael Roberts , Moonsun Kim , Myron Jacobson , Elaine Jacobson
发明人: Georg Wondrak , Michael Roberts , Moonsun Kim , Myron Jacobson , Elaine Jacobson
IPC分类号: C07D207/16 , A61K20060101 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/44 , A61K8/49 , A61K8/65 , A61K31/401 , A61K31/4015 , A61K31/44 , A61K31/4415 , A61K31/455 , A61K45/00 , A61P17/16 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61K7/42
CPC分类号: A61Q19/004 , A61K8/4913 , A61K8/4926 , A61K31/401 , A61K31/44 , A61K2800/57 , A61Q17/04 , A61Q19/00
摘要: The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.
摘要翻译: 本发明涉及通过使用增强或抑制由紫外光引起的损伤的胶原衍生分子调节光损伤的方法。
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公开(公告)号:US20050197400A1
公开(公告)日:2005-09-08
申请号:US11069292
申请日:2005-03-01
申请人: Georg Wondrak , Myron Jacobson , Elaine Jacobson
发明人: Georg Wondrak , Myron Jacobson , Elaine Jacobson
IPC分类号: A61K31/155 , A61K31/195 , A61K31/198
CPC分类号: A61K31/155 , A61K31/195 , A61K31/198
摘要: Carbonyl scavengers, which have been recognized for their ability to react with reactive carbonyl species, have been implicated as agents that can accelerate or induce the death of abnormal cells without having a parallel effect on normal cells. As such, they are useful therapeutic agents in cases where the acceleration or induction of cell death is desirable, such as in cells where the normal apoptotic pathways have been disrupted and where hyperproliferative cell growth occurs.
摘要翻译: 被认为与反应性羰基物质反应的能力的羰基清除剂已经被认为是可以加速或诱导异常细胞死亡但不对正常细胞具有平行作用的试剂。 因此,在需要加速或诱导细胞死亡的情况下,例如在正常凋亡途径被破坏并且发生过度增殖细胞生长的细胞中,它们是有用的治疗剂。
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