Method for inducing cell death with carbonyl scavengers
    3.
    发明申请
    Method for inducing cell death with carbonyl scavengers 有权
    用羰基清除剂诱导细胞死亡的方法

    公开(公告)号:US20050197400A1

    公开(公告)日:2005-09-08

    申请号:US11069292

    申请日:2005-03-01

    摘要: Carbonyl scavengers, which have been recognized for their ability to react with reactive carbonyl species, have been implicated as agents that can accelerate or induce the death of abnormal cells without having a parallel effect on normal cells. As such, they are useful therapeutic agents in cases where the acceleration or induction of cell death is desirable, such as in cells where the normal apoptotic pathways have been disrupted and where hyperproliferative cell growth occurs.

    摘要翻译: 被认为与反应性羰基物质反应的能力的羰基清除剂已经被认为是可以加速或诱导异常细胞死亡但不对正常细胞具有平行作用的试剂。 因此,在需要加速或诱导细胞死亡的情况下,例如在正常凋亡途径被破坏并且发生过度增殖细胞生长的细胞中,它们是有用的治疗剂。