公开(公告)号：US20150024113A1

公开(公告)日：2015-01-22

申请号：US14492193

申请日：2014-09-22

Applicant: Grain Processing Corporation

Inventor： Lin Wang ,  Peter Miller ,  Tonya Armstrong ,  Michael Kramer ,  Susan Freers ,  Roger McPherson ,  Daniel Hubbard ,  Terry Andren ,  Jeff Underwood

IPC: C08J3/03 ,  A23L1/00 ,  A23L1/22 ,  A61K47/36 ,  A61K9/28

CPC classification number: C08L3/08 ,  A23L7/122 ,  A23L11/01 ,  A23L25/25 ,  A23L27/00 ,  A23P20/10 ,  A23P20/12 ,  A23V2002/00 ,  A61K9/286 ,  A61K47/36 ,  B29C47/0021 ,  B29C47/889 ,  B29C47/92 ,  B29C2947/9259 ,  B29C2947/92704 ,  B29C2947/92885 ,  B29C2947/92895 ,  C08B30/14 ,  C08B31/12 ,  C08J3/03 ,  C08J5/18 ,  C08J2301/08 ,  C08J2303/04 ,  C08K5/0016 ,  C09D101/284 ,  C09D103/02 ,  C09D103/08 ,  C09D191/00 ,  E04B2/767 ,  E04B2/96 ,  E04B2001/2415 ,  E04B2001/2439 ,  E04B2001/405 ,  C08L3/02 ,  C08L1/284

Abstract: Disclosed is a cold-water soluble starch and a process for preparing same. Generally, the process comprises providing a hydroxyalkyl starch and applying a shearing force to the starch in an extruder in the presence of moisture, the force and the moisture each being sufficient to gelatinize at least substantially all of the granules of the starch to thereby form a sheared starch. The starch is heated to its gelatinization temperature after the starch has passed partially through the barrel of the extruder, with the moisture being maintained at a level sufficiently high to allow gelatinization but sufficiency low to protect the starch from becoming too sticky to extrude. The extruded starch product thus formed may be used in connection with a number of film-forming, coating, and other applications.

Abstract translation: 公开了一种冷水可溶性淀粉及其制备方法。 通常，该方法包括提供羟烷基淀粉并在存在水分的情况下在挤出机中对淀粉施加剪切力，所述力和水分各自足以使至少基本上所有的淀粉颗粒胶凝，由此形成 剪切淀粉。 在淀粉部分地通过挤出机的筒体之后，将淀粉加热到其凝胶化温度，其中水分保持在足够高的水平以允许糊化，但足够低以保护淀粉变得太粘而不能挤出。 如此形成的挤出淀粉产品可与许多成膜，涂布和其它应用相结合使用。

公开(公告)号：US09605141B2

公开(公告)日：2017-03-28

申请号：US14492193

申请日：2014-09-22

Applicant: Grain Processing Corporation

Inventor： Lin Wang ,  Peter Miller ,  Tonya Armstrong ,  Michael Kramer ,  Susan Freers ,  Roger McPherson ,  Daniel Hubbard ,  Terry Andren ,  Jeff Underwood

IPC: A23L1/05 ,  C08L3/08 ,  C08B30/14 ,  C08B31/12 ,  C08J5/18 ,  C09D101/28 ,  C09D103/02 ,  C09D103/08 ,  C09D191/00 ,  E04B2/76 ,  E04B2/96 ,  B29C47/92 ,  A61K9/28 ,  A61K47/36 ,  C08J3/03 ,  B29C47/88 ,  A23P20/10 ,  A23P20/12 ,  A23L27/00 ,  A23L25/00 ,  B29C47/00 ,  C08K5/00 ,  E04B1/24 ,  E04B1/38 ,  A23L7/122 ,  A23L11/00

CPC classification number: C08L3/08 ,  A23L7/122 ,  A23L11/01 ,  A23L25/25 ,  A23L27/00 ,  A23P20/10 ,  A23P20/12 ,  A23V2002/00 ,  A61K9/286 ,  A61K47/36 ,  B29C47/0021 ,  B29C47/889 ,  B29C47/92 ,  B29C2947/9259 ,  B29C2947/92704 ,  B29C2947/92885 ,  B29C2947/92895 ,  C08B30/14 ,  C08B31/12 ,  C08J3/03 ,  C08J5/18 ,  C08J2301/08 ,  C08J2303/04 ,  C08K5/0016 ,  C09D101/284 ,  C09D103/02 ,  C09D103/08 ,  C09D191/00 ,  E04B2/767 ,  E04B2/96 ,  E04B2001/2415 ,  E04B2001/2439 ,  E04B2001/405 ,  C08L3/02 ,  C08L1/284

Abstract: Disclosed is a cold-water soluble starch and a process for preparing same. Generally, the process comprises providing a hydroxyalkyl starch and applying a shearing force to the starch in an extruder in the presence of moisture, the force and the moisture each being sufficient to gelatinize at least substantially all of the granules of the starch to thereby form a sheared starch. The starch is heated to its gelatinization temperature after the starch has passed partially through the barrel of the extruder, with the moisture being maintained at a level sufficiently high to allow gelatinization but sufficiency low to protect the starch from becoming too sticky to extrude. The extruded starch product thus formed may be used in connection with a number of film-forming, coating, and other applications.

公开(公告)号：US20140079786A1

公开(公告)日：2014-03-20

申请号：US14031781

申请日：2013-09-19

Applicant: Grain Processing Corporation

Inventor： Susan Freers ,  Carrie Shipley ,  Brian Jensen ,  Shawn Engels

IPC: A61K47/46 ,  A23L1/308

CPC classification number: A61K47/46 ,  A23L7/115 ,  A23L29/35 ,  A23L33/21 ,  A23L33/22 ,  A61K9/1676 ,  A61K31/192

Abstract: The disclosure pertains generally to spheres made from a fiber source. These spheres may be used as cores for carrying other ingredients or may be used alone for applications in the food, pharmaceutical, nutraceutical, personal care, and industrial industries. In many embodiments the ingredients used in this invention are derived from a natural resource, and are safe to ingest. In some embodiments, the spheres are formed using a centrifugal tumbling-granulating-coating apparatus.

Abstract translation: 本公开一般涉及由纤维源制成的球体。 这些球体可以用作承载其他成分的核心，或者可以单独用于食品，制药，保健品，个人护理和工业工业中的应用。 在许多实施方案中，本发明中使用的成分来自天然资源，并且是安全的摄取。 在一些实施例中，使用离心滚筒造粒涂布装置形成球体。

公开(公告)号：US20130071479A1

公开(公告)日：2013-03-21

申请号：US13623591

申请日：2012-09-20

Applicant: Grain Processing Corporation

Inventor： Susan Freers ,  Carrie Shipley ,  Brian Jensen ,  Shawn Engels

IPC: A61K9/14 ,  B05D5/00

CPC classification number: A61K9/5078 ,  A61K9/1652 ,  A61K9/5036 ,  Y10T428/2989

Abstract: The disclosure relates to substantially uniform, high density microspheres and methods of making the microspheres. The microspheres can be made to be small in size with a narrow range of particle size distribution and a high sphericity. In one aspect, the microspheres provided herein are provided in the form of spherical cores comprising maltodextrin or maltodextrin and starch and are prepared using a centrifugal tumbling-granulating-coating apparatus. In another aspect, the spherical cores can be powder-coated with one or more layers of small particles, such as starch particles. The microspheres provided herein can be used as cores for multi-particulate solid dosage delivery systems as well as other pharmaceutical, nutraceutical, food, personal care, and other applications.

Abstract translation: 本公开涉及基本均匀的高密度微球体和制备微球体的方法。 微球可以制成尺寸小，粒径分布窄，球形度高。 在一个方面，本文提供的微球以包含麦芽糖糊精或麦芽糖糊精和淀粉的球形芯的形式提供，并且使用离心转鼓造粒包衣设备制备。 另一方面，球形芯可以粉末涂覆一层或多层小颗粒，如淀粉颗粒。 本文提供的微球可用作多颗粒固体剂量递送系统的核心，以及其它药物，保健食品，食品，个人护理和其它应用。

公开(公告)号：US09918942B2

公开(公告)日：2018-03-20

申请号：US13623591

申请日：2012-09-20

Applicant: Grain Processing Corporation

Inventor： Susan Freers ,  Carrie Shipley ,  Brian Jensen ,  Shawn Engels

IPC: A61K9/14 ,  B05D5/00 ,  A61K9/50 ,  A61K9/16

CPC classification number: A61K9/5078 ,  A61K9/1652 ,  A61K9/5036 ,  Y10T428/2989

Abstract: The disclosure relates to substantially uniform, high density microspheres and methods of making the microspheres. The microspheres can be made to be small in size with a narrow range of particle size distribution and a high sphericity. In one aspect, the microspheres provided herein are provided in the form of spherical cores comprising maltodextrin or maltodextrin and starch and are prepared using a centrifugal tumbling-granulating-coating apparatus. In another aspect, the spherical cores can be powder-coated with one or more layers of small particles, such as starch particles. The microspheres provided herein can be used as cores for multi-particulate solid dosage delivery systems as well as other pharmaceutical, nutraceutical, food, personal care, and other applications.