公开(公告)号：US20070299405A1

公开(公告)日：2007-12-27

申请号：US11750017

申请日：2007-05-17

申请人： Heiner Kaufmann ,  Florian Kuhni ,  Axel Remde ,  Gerald Studer ,  Michael Haberli

发明人： Heiner Kaufmann ,  Florian Kuhni ,  Axel Remde ,  Gerald Studer ,  Michael Haberli

IPC分类号： A61M25/02

CPC分类号： A61M5/14248 ,  A61M2005/14252 ,  A61M2005/1581 ,  A61M2005/1587

摘要： An infusion arrangement and method for administering a medicinal substance to a patient, the arrangement including a catheter head with an underside for securing to the patients' body, a cannula extending from the underside of the catheter head for insertion into the patient's body, a connector carried on the catheter head for establishing a releasable fluidic connection to an administration device, the administration device rotatably coupled to the connector, wherein the administration device carries, on peripheral areas of the underside thereof, at least one adhesive suitable for fixing the administration device in a selected position relative to the patient's body.

摘要翻译： 一种用于向患者施用药物的输注装置和方法，所述装置包括具有用于固定到患者身体的下侧的导管头，从导管头的下侧延伸以用于插入到患者体内的套管，连接器 承载在导管头上以建立与给药装置的可释放的流体连接，所述给药装置可旋转地联接到所述连接器，其中所述给药装置在其下侧的周边区域上携带至少一种适合于将所述给药装置固定的粘合剂 相对于患者身体的选定位置。

公开(公告)号：US20080004573A1

公开(公告)日：2008-01-03

申请号：US11750652

申请日：2007-05-18

申请人： Heiner Kaufmann ,  Florian Kuhni ,  Axel Remde ,  Gerald Studer

发明人： Heiner Kaufmann ,  Florian Kuhni ,  Axel Remde ,  Gerald Studer

IPC分类号： A61M5/32

CPC分类号： A61M5/14248 ,  A61M2005/14252 ,  A61M2005/1581

摘要： An auxiliary adapter with which a medical appliance carrying an adhesive can be applied to the skin of a human or animal body, wherein the adapter may be connected to or integral with the medical appliance and, in some embodiments, includes a fixing structure or portion generally correlative with a pivot mechanism associated with the medical appliance. Using the adapter, the medical appliance may be applied to the skin surface ergonomically and comfortably, and as precisely and securely as possible.

摘要翻译： 可以将携带粘合剂的医疗器具的辅助适配器施加到人或动物体的皮肤上，其中适配器可以连接到医疗器具或与医疗器具一体，并且在一些实施例中，包括固定结构或部分 与与医疗器具相关联的枢转机构相关。 使用适配器，医疗器具可以以人体工程学和舒适的方式并且尽可能精确和安全地应用于皮肤表面。

公开(公告)号：US20100030483A1

公开(公告)日：2010-02-04

申请号：US12511190

申请日：2009-07-29

申请人： Thomas Vering ,  Florian Kuhni ,  Lucas Kalt ,  Catalin Cris ,  Caroline Patte

发明人： Thomas Vering ,  Florian Kuhni ,  Lucas Kalt ,  Catalin Cris ,  Caroline Patte

IPC分类号： G06F19/00 ,  G01N33/48

CPC分类号： A61B5/14532 ,  A61B5/7275 ,  A61B5/7285 ,  G06F19/00 ,  G06F19/324 ,  G06F19/3456 ,  G16H50/20

摘要： Embodiments of an assessment method for processing a signal corresponding to a glucose concentration and performing a retrospective analysis comprises the steps of: a) initiating a first trigger, wherein the first trigger defines the beginning of a segment of a continuous measurement of glucose concentration or defines the first of a series of spot measurements of glucose concentration; b) collecting data of the continuous measurement or the series of spot measurements of glucose concentration to be analyzed, wherein the collected data relates to a glucose concentration excursion corresponding to a reaction to a relevant event such as a meal or physical activity; c) analyzing the collected data initiated by a second trigger, wherein the second trigger defines the end of the collected data to be analyzed, wherein a measure for a grading of the excursion is determined from the collected data, and d) displaying the results of the analysis.

摘要翻译： 用于处理对应于葡萄糖浓度并进行回顾性分析的信号的评估方法的实施方案包括以下步骤：a）启动第一触发，其中第一触发器定义连续测量葡萄糖浓度的段的开始或定义 首先对葡萄糖浓度进行一系列点测量; b）收集要分析的葡萄糖浓度的连续测量或点测量的数据，其中所收集的数据涉及对应于对诸如膳食或身体活动的相关事件的反应的葡萄糖浓度偏移; c）分析由第二触发器发起的所收集的数据，其中所述第二触发器定义所述被分析数据的结束，其中根据所收集的数据确定所述偏移的分级的度量，以及d）显示所述数据的结果 分析。

公开(公告)号：US08602067B2

公开(公告)日：2013-12-10

申请号：US12792138

申请日：2010-06-02

申请人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

发明人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

IPC分类号： B65B31/04 ,  A61J1/00 ,  A61M5/142

CPC分类号： B65B31/025 ,  A61J1/10 ,  A61J1/20 ,  A61M5/14216 ,  A61M2209/045

摘要： A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.

摘要翻译： 公开了一种用于填充柔性容器的装置及其方法。 该装置可以包括加压室和排气室。 第一位移活塞被密封地和可滑动地布置在加压室内，以限定加压室内的内部容积，其流体地连接到加压管道。 第二位移活塞可密封地且可滑动地布置在排气室内，以限定抽空室内的内部容积，其流体地连接到排气管道。 储液器适配器流体地连接到加压管道并连接到液体储存器。 容器适配器流体地连接到排气管并与柔性容器连接。 转移导管流体连接到储存器适配器和容器适配器。 阀门将容器适配器流体地连接到排气管道或输送管道。

公开(公告)号：US09089647B2

公开(公告)日：2015-07-28

申请号：US13492008

申请日：2012-06-08

申请人： Roger Haenggi ,  Urs Rindlisbacher ,  Franco Moia ,  Marcel Mueller ,  Christoph Huwiler ,  Florian Kuhni ,  Joerg Wermelinger ,  Andreas Lischewski ,  Christian Classen ,  Tilo Callenbach ,  Louis Widmer ,  Maurice Ducret

发明人： Roger Haenggi ,  Urs Rindlisbacher ,  Franco Moia ,  Marcel Mueller ,  Christoph Huwiler ,  Florian Kuhni ,  Joerg Wermelinger ,  Andreas Lischewski ,  Christian Classen ,  Tilo Callenbach ,  Louis Widmer ,  Maurice Ducret

IPC分类号： A61B19/00 ,  A61M5/24

CPC分类号： A61J1/2096 ,  A61J1/20 ,  A61J1/201 ,  A61J1/2048 ,  A61M5/24 ,  B65B3/003

摘要： In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

摘要翻译： 在一个实施例中，从药物储存器填充液体药物的容器的方法可以包括：a）将容器和药物储存器与套管连接，使得药物储存器和容器经由套管彼此流体连通， 同时密封; b）减少容纳在容器内的第一容积，以将气态介质从容器的第一容积经由套管置换成容纳在药物贮存器内的第二容积; c）增加容器的第一容积以将液体药物从药物储存器的第二体积移位到容器的第一容积中以填充容器; 和d）断开容器和药物储存器。 在执行动作d）之前，动作b）和动作c）可以连续执行多次以逐步增加液体药物的移动量。

公开(公告)号：US08313468B2

公开(公告)日：2012-11-20

申请号：US12725819

申请日：2010-03-17

申请人： Andreas Geipel ,  Florian Kuhni ,  Christoph Huwiler ,  Ulrich Haueter

发明人： Andreas Geipel ,  Florian Kuhni ,  Christoph Huwiler ,  Ulrich Haueter

IPC分类号： A61M5/162 ,  G01L9/12

CPC分类号： A61M5/158 ,  A61M5/16854 ,  A61M2205/0244 ,  A61M2205/33 ,  A61M2205/3331 ,  G01L9/0005 ,  G01L9/0041

摘要： Cannula assemblies with pressure sensors made of stacked coplanar layers and ambulatory infusion systems comprising the same are disclosed. The cannula assemblies include a hub and an infusion cannula. The hub includes a pressure sensor and a fluid channel fluidly coupled to the infusion cannula. The pressure sensor is formed from a stack of coplanar layers including a top layer, a base layer an electrode layer and a counter electrode layer. The fluid channel is positioned between the top layer and the base layer. The electrode layer is positioned between the top layer and the base layer and coupled to the fluid channel. The counter-electrode layer is positioned between the top layer and the electrode layer. A spacer layer having a through cut-out defining an electrode cavity is disposed between the top layer and the base layer such that the electrode layer extends across the electrode cavity.

摘要翻译： 公开了具有由堆叠的共面层制成的压力传感器和包括其的动态输注系统的插管组件。 套管组件包括轮毂和输液套管。 毂包括压力传感器和流体地联接到输注套管的流体通道。 压力传感器由包括顶层，基底层，电极层和对电极层的共面层组成。 流体通道位于顶层和基层之间。 电极层位于顶层和底层之间，并连接到流体通道。 对电极层位于顶层和电极层之间。 具有限定电极腔的通孔的间隔层设置在顶层和基层之间，使得电极层延伸穿过电极腔。

公开(公告)号：US20110132490A1

公开(公告)日：2011-06-09

申请号：US12792138

申请日：2010-06-02

申请人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

发明人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

IPC分类号： A61J1/00 ,  B65B3/17 ,  B65B31/00

CPC分类号： B65B31/025 ,  A61J1/10 ,  A61J1/20 ,  A61M5/14216 ,  A61M2209/045

摘要： A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.

摘要翻译： 公开了一种用于填充柔性容器的装置及其方法。 该装置可以包括加压室和排气室。 第一位移活塞被密封地和可滑动地布置在加压室内，以限定加压室内的内部容积，其流体地连接到加压管道。 第二位移活塞可密封地且可滑动地布置在排气室内，以限定抽空室内的内部容积，其流体地连接到排气管道。 储液器适配器流体地连接到加压管道并连接到液体储存器。 容器适配器流体地连接到排气管并与柔性容器连接。 转移导管流体连接到储存器适配器和容器适配器。 阀门将容器适配器流体地连接到排气管道或输送管道。

公开(公告)号：US20100241077A1

公开(公告)日：2010-09-23

申请号：US12725819

申请日：2010-03-17

申请人： Andreas Geipel ,  Florian Kuhni ,  Christoph Huwiler ,  Ulrich Haueter

发明人： Andreas Geipel ,  Florian Kuhni ,  Christoph Huwiler ,  Ulrich Haueter

IPC分类号： A61M5/162 ,  A61M5/142 ,  G01L9/12

CPC分类号： A61M5/158 ,  A61M5/16854 ,  A61M2205/0244 ,  A61M2205/33 ,  A61M2205/3331 ,  G01L9/0005 ,  G01L9/0041

摘要： Cannula assemblies with pressure sensors made of stacked coplanar layers and ambulatory infusion systems comprising the same are disclosed. The cannula assemblies include a hub and an infusion cannula. The hub includes a pressure sensor and a fluid channel fluidly coupled to the infusion cannula. The pressure sensor is formed from a stack of coplanar layers including a top layer, a base layer an electrode layer and a counter electrode layer. The fluid channel is positioned between the top layer and the base layer. The electrode layer is positioned between the top layer and the base layer and coupled to the fluid channel. The counter-electrode layer is positioned between the top layer and the electrode layer. A spacer layer having a through cut-out defining an electrode cavity is disposed between the top layer and the base layer such that the electrode layer extends across the electrode cavity.

摘要翻译： 公开了具有由堆叠的共面层制成的压力传感器和包括其的动态输注系统的插管组件。 套管组件包括轮毂和输液套管。 毂包括压力传感器和流体地联接到输注套管的流体通道。 压力传感器由包括顶层，基底层，电极层和对电极层的共面层组成。 流体通道位于顶层和基层之间。 电极层位于顶层和底层之间，并连接到流体通道。 对电极层位于顶层和电极层之间。 具有限定电极腔的通孔的间隔层设置在顶层和基层之间，使得电极层延伸穿过电极腔。

公开(公告)号：US20130035658A1

公开(公告)日：2013-02-07

申请号：US13492008

申请日：2012-06-08

申请人： Roger Haenggi ,  Urs Rindlisbacher ,  Franco Moia ,  Marcel Mueller ,  Christoph Huwiler ,  Florian Kuhni ,  Joerg Wermelinger ,  Andreas Lischewski ,  Christian Classen ,  Tilo Callenbach ,  Louis Widmer ,  Maurice Ducret

发明人： Roger Haenggi ,  Urs Rindlisbacher ,  Franco Moia ,  Marcel Mueller ,  Christoph Huwiler ,  Florian Kuhni ,  Joerg Wermelinger ,  Andreas Lischewski ,  Christian Classen ,  Tilo Callenbach ,  Louis Widmer ,  Maurice Ducret

IPC分类号： A61J1/20 ,  A61J1/10

CPC分类号： A61J1/2096 ,  A61J1/20 ,  A61J1/201 ,  A61J1/2048 ,  A61M5/24 ,  B65B3/003

摘要： In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

摘要翻译： 在一个实施例中，从药物储存器填充液体药物的容器的方法可以包括：a）将容器和药物储存器与套管连接，使得药物储存器和容器经由套管彼此流体连通， 同时密封; b）减少容纳在容器内的第一容积，以将气态介质从容器的第一容积经由套管置换成容纳在药物贮存器内的第二容积; c）增加容器的第一容积以将液体药物从药物储存器的第二体积移位到容器的第一容积中以填充容器; 和d）断开容器和药物储存器。 在执行动作d）之前，动作b）和动作c）可以连续执行多次以逐步增加液体药物的移动量。

公开(公告)号：US08060318B2

公开(公告)日：2011-11-15

申请号：US12511190

申请日：2009-07-29

申请人： Thomas Vering ,  Florian Kuhni ,  Lucas Kalt ,  Catalin Cris ,  Caroline Patte

发明人： Thomas Vering ,  Florian Kuhni ,  Lucas Kalt ,  Catalin Cris ,  Caroline Patte

IPC分类号： G06F19/00 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/7275 ,  A61B5/7285 ,  G06F19/00 ,  G06F19/324 ,  G06F19/3456 ,  G16H50/20

摘要： Embodiments of an assessment method for processing a signal corresponding to a glucose concentration and performing a retrospective analysis comprises the steps of: a) initiating a first trigger, wherein the first trigger defines the beginning of a segment of a continuous measurement of glucose concentration or defines the first of a series of spot measurements of glucose concentration; b) collecting data of the continuous measurement or the series of spot measurements of glucose concentration to be analyzed, wherein the collected data relates to a glucose concentration excursion corresponding to a reaction to a relevant event such as a meal or physical activity; c) analyzing the collected data initiated by a second trigger, wherein the second trigger defines the end of the collected data to be analyzed, wherein a measure for a grading of the excursion is determined from the collected data, and d) displaying the results of the analysis.

摘要翻译： 用于处理对应于葡萄糖浓度并进行回顾性分析的信号的评估方法的实施方案包括以下步骤：a）启动第一触发，其中第一触发器定义连续测量葡萄糖浓度的段的开始或定义 首先对葡萄糖浓度进行一系列点测量; b）收集要分析的葡萄糖浓度的连续测量或点测量的数据，其中所收集的数据涉及对应于对诸如膳食或身体活动的相关事件的反应的葡萄糖浓度偏移; c）分析由第二触发器发起的所收集的数据，其中所述第二触发器定义所述被分析数据的结束，其中根据所收集的数据确定所述偏移的分级的度量，以及d）显示所述数据的结果 分析。