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公开(公告)号：US09603998B2
公开(公告)日：2017-03-28
申请号：US12877569
申请日：2010-09-08
Applicant: Andreas Geipel , Christoph Huwiler , Florian Kühni
Inventor： Andreas Geipel , Christoph Huwiler , Florian Kühni
CPC classification number: A61M5/141 , A61M5/16877 , A61M5/36 , A61M2205/0244 , A61M2205/3331 , G01R33/302 , Y10T137/0318 , Y10T137/8326 , Y10T137/8593
Abstract: Micro-fluidic chambers for use in a liquid medicament delivery system, include a bottom substrate and a top cover, the top cover being spaced from the bottom substrate so as to define a height of the chamber, wherein, one or more walls or fillings are positioned in the chamber, the walls or fillings defining a fluid channel there between such that the fluid channel extends from an inlet of the chamber to an outlet of the chamber, wherein, each of the walls or fillings has a height less than the height of the chamber so as to define a fluid gap between a top surface of each wall or filling and the top cover; and wherein, the dimensions of the walls or fillings and the chamber are such that the fluid gap will be filled with liquid by capillary forces via the fluid channel when liquid is introduced into the fluid chamber.
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2.发明申请Cannula Assemblies And Ambulatory Infusion Systems With Pressure Sensors Made Of Stacked Coplanar Layers 有权插管组件和动态输液系统与压力传感器由堆叠的共面层公开(公告)号：US20100241077A1
公开(公告)日：2010-09-23
申请号：US12725819
申请日：2010-03-17
Applicant: Andreas Geipel , Florian Kuhni , Christoph Huwiler , Ulrich Haueter
Inventor： Andreas Geipel , Florian Kuhni , Christoph Huwiler , Ulrich Haueter
CPC classification number: A61M5/158 , A61M5/16854 , A61M2205/0244 , A61M2205/33 , A61M2205/3331 , G01L9/0005 , G01L9/0041
Abstract: Cannula assemblies with pressure sensors made of stacked coplanar layers and ambulatory infusion systems comprising the same are disclosed. The cannula assemblies include a hub and an infusion cannula. The hub includes a pressure sensor and a fluid channel fluidly coupled to the infusion cannula. The pressure sensor is formed from a stack of coplanar layers including a top layer, a base layer an electrode layer and a counter electrode layer. The fluid channel is positioned between the top layer and the base layer. The electrode layer is positioned between the top layer and the base layer and coupled to the fluid channel. The counter-electrode layer is positioned between the top layer and the electrode layer. A spacer layer having a through cut-out defining an electrode cavity is disposed between the top layer and the base layer such that the electrode layer extends across the electrode cavity.
Abstract translation: 公开了具有由堆叠的共面层制成的压力传感器和包括其的动态输注系统的插管组件。 套管组件包括轮毂和输液套管。 毂包括压力传感器和流体地联接到输注套管的流体通道。 压力传感器由包括顶层，基底层，电极层和对电极层的共面层组成。 流体通道位于顶层和基层之间。 电极层位于顶层和底层之间，并连接到流体通道。 对电极层位于顶层和电极层之间。 具有限定电极腔的通孔的间隔层设置在顶层和基层之间，使得电极层延伸穿过电极腔。
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3.发明申请公开(公告)号：US20100125245A1
公开(公告)日：2010-05-20
申请号：US12615338
申请日：2009-11-10
Applicant: Andreas Geipel
Inventor： Andreas Geipel
CPC classification number: G01L7/00 , A61M5/141 , A61M5/16854 , A61M2205/3386 , G01K5/28 , G01L11/00 , Y10T137/87265 , Y10T137/87338
Abstract: A device for detecting pressure and/or temperature changes in a fluid-channel and method thereof are disclosed. The device includes a main duct with an inlet and an outlet, a branch ductwork with a first branch end branching off the main duct downwards the inlet and with a second branch end discharging into the main duct upwards the outlet, and at least one dead-end channel with a first end that branches off the branch ductwork and a second closed end. The dead-end channel is adapted to trap a gas bubble within the dead-end channel when the device is primed or filled with a liquid fluid, wherein the gas bubble changes its size or position if a change in pressure or temperature occurs in the device.
Abstract translation: 公开了一种用于检测流体通道中的压力和/或温度变化的装置及其方法。 该装置包括具有入口和出口的主管道，分支管道系统，其具有第一分支端部，从主管道向下分离出入口，并且第二分支端部向上排放到主管道上方，以及至少一个死区， 末端通道具有从分支管道系统分支的第一端和第二闭合端。 该死端通道适于在装置被灌注或填充有液体流体时将气泡捕获在死端通道内，其中如果在装置中发生压力或温度的变化，则气泡改变其大小或位置 。
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公开(公告)号：US20140046288A1
公开(公告)日：2014-02-13
申请号：US14049396
申请日：2013-10-09
Applicant: Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
Inventor： Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
CPC classification number: A61M5/16809 , A61M5/142 , A61M5/14216 , A61M5/31511 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14264 , A61M2005/16868 , A61M2205/3306 , A61M2205/3355 , A61M2205/3365 , A61M2205/3396
Abstract: An infusion pump device comprising a primary liquid medicament reservoir, a pump with a secondary reservoir to retrieve medicament from the primary reservoir and to subsequently dose the medicament from the secondary reservoir in adjustable volumes (Vdose,i) to a downstream conduit and a control unit to control the operation of the infusion pump device is presented. For metering the volumes (Vdose,i), the control unit causes the infusion pump device to: (a) determine a maximum refill level (VC,max) for the secondary reservoir, based on external parameters, wherein the maximum refill level does not exceed the maximum capacity of the secondary reservoir; (b) fill the secondary reservoir with medicament from the primary reservoir to the maximum refill level (VC,max); (c) meter and convey the medicament volumes to the downstream conduit; (d) if the secondary reservoir becomes empty, refill the secondary reservoir as in step (b) and continue with step (c).
Abstract translation: 一种输液泵装置，包括初级液体药物储存器，具有辅助贮存器的泵，用于从主储存器检索药物，并且随后以可调节的体积（Vdose，i）向下游管道和控制单元 以控制输液泵装置的操作。 为了计量体积（Vdose，i），控制单元使输液泵装置：（a）基于外部参数确定次级储存器的最大补充水平（VC，最大值），其中最大补充水平不 超过次级水库的最大容量; （b）将副储存器从主贮存器填充至最大补充水平（VC，max）; （c）计量并将药物体积输送到下游导管; （d）如果二次储存器变空，则如步骤（b）中那样重新填充次级储存器，并继续步骤（c）。
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5.发明授权Cannula assemblies and ambulatory infusion systems with pressure sensors made of stacked coplanar layers 有权插管组件和动态输液系统，压力传感器由堆叠的共面层组成公开(公告)号：US08313468B2
公开(公告)日：2012-11-20
申请号：US12725819
申请日：2010-03-17
Applicant: Andreas Geipel , Florian Kuhni , Christoph Huwiler , Ulrich Haueter
Inventor： Andreas Geipel , Florian Kuhni , Christoph Huwiler , Ulrich Haueter
CPC classification number: A61M5/158 , A61M5/16854 , A61M2205/0244 , A61M2205/33 , A61M2205/3331 , G01L9/0005 , G01L9/0041
Abstract: Cannula assemblies with pressure sensors made of stacked coplanar layers and ambulatory infusion systems comprising the same are disclosed. The cannula assemblies include a hub and an infusion cannula. The hub includes a pressure sensor and a fluid channel fluidly coupled to the infusion cannula. The pressure sensor is formed from a stack of coplanar layers including a top layer, a base layer an electrode layer and a counter electrode layer. The fluid channel is positioned between the top layer and the base layer. The electrode layer is positioned between the top layer and the base layer and coupled to the fluid channel. The counter-electrode layer is positioned between the top layer and the electrode layer. A spacer layer having a through cut-out defining an electrode cavity is disposed between the top layer and the base layer such that the electrode layer extends across the electrode cavity.
Abstract translation: 公开了具有由堆叠的共面层制成的压力传感器和包括其的动态输注系统的插管组件。 套管组件包括轮毂和输液套管。 毂包括压力传感器和流体地联接到输注套管的流体通道。 压力传感器由包括顶层，基底层，电极层和对电极层的共面层组成。 流体通道位于顶层和基层之间。 电极层位于顶层和底层之间，并连接到流体通道。 对电极层位于顶层和电极层之间。 具有限定电极腔的通孔的间隔层设置在顶层和基层之间，使得电极层延伸穿过电极腔。
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Patent Agency Ranking
6.发明申请MODULAR INFUSION SET WITH AN INTEGRATED ELECTRICALLY POWERED FUNCTIONAL COMPONENT 审中-公开具有集成电力功能部件的模块化输液公开(公告)号：US20120029333A1
公开(公告)日：2012-02-02
申请号：US13015063
申请日：2011-01-27
Applicant: Joerg Dogwiler , Andreas Geipel , David Teutsch , Christoph Huwiler
Inventor： Joerg Dogwiler , Andreas Geipel , David Teutsch , Christoph Huwiler
CPC classification number: A61M5/158 , A61M5/1413 , A61M5/142 , A61M5/16854 , A61M5/36 , A61M2005/1587 , A61M2005/1588 , A61M2005/16863 , A61M2039/1022 , A61M2205/13 , A61M2205/3306 , A61M2205/3331 , A61M2205/3368 , A61M2205/3592 , A61M2205/8206 , A61M2230/63
Abstract: An infusion set for administering a medicament delivered by an infusion pump which can be carried separately from the infusion set as well as an infusion system including the infusion set are disclosed. The infusion set can comprise a disposable part, a reusable part, and an electrically powered functional component. The disposable part can comprise a single lumen infusion cannula that projects from the underside and is the only skin piercing or penetrating element of the infusion set. The reusable part when in the interconnected state is fluidically isolated from the disposable part. The disposable part can comprise a feeding line which fluidically connects an upstream end of the first connector with a downstream end of a cannula to feed and deliver the medicament via the disposable part and bypass the reusable part.
Abstract translation: 公开了一种用于施用由输注泵输送的药物的输液器，其可以与输液器分开携带，以及包括输注器的输注系统。 输注组件可以包括一次性部件，可重复使用部件和电动功能部件。 一次性部分可以包括从下侧突出并且是输注组的唯一皮肤刺穿或穿透元件的单腔输注套管。 处于互连状态的可重复使用部分与一次性部件流体隔离。 一次性部件可以包括馈送线，其将第一连接器的上游端与套管的下游端流体连接，以通过一次性部分供给和输送药物并绕过可再使用部件。
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公开(公告)号：US09724267B2
公开(公告)日：2017-08-08
申请号：US13894834
申请日：2013-05-15
Applicant: Martin Wyss , Rudolf Zihlmann , Gerald Studer , Andreas Geipel , Davide Crotta
Inventor： Martin Wyss , Rudolf Zihlmann , Gerald Studer , Andreas Geipel , Davide Crotta
Abstract: A container for storing a medical or pharmaceutical liquid comprising a storage compartment for storing the liquid comprising, an inlet opening for filling the storage compartment and an outlet opening for discharging liquid out of the storage compartment is presented. A hydrophilic membrane layer is arranged within the storage compartment which is gas-tight in a wet condition and which at least covers the outlet opening and contacts the liquid stored within the storage compartment. A dosing assembly and a device for automated release of a medical or pharmaceutical liquid comprising and/or capable of using at least one container are also disclosed.
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公开(公告)号：US20140039396A1
公开(公告)日：2014-02-06
申请号：US14049528
申请日：2013-10-09
Applicant: Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
Inventor： Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
CPC classification number: A61M5/172 , A61M5/14216 , A61M5/14244 , A61M5/16809 , A61M5/31511 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14264 , A61M2005/16868 , A61M2205/3306 , A61M2205/3355 , A61M2205/3365 , A61M2205/3396
Abstract: A dosing unit for an ambulatory infusion pump device is presented. The dosing unit comprises a cylinder pump with a cylinder and a piston arranged in the cylinder. The piston has a shaft with a first threaded segment interacting with a threaded portion of the cylinder and can be displaced along a longitudinal axis of the cylinder by rotating the piston in regard to the cylinder around the axis. Furthermore, the piston allows for the relative or absolute determination of the longitudinal and/or rotational displacement of the piston in regard to the cylinder. In one embodiment, the piston shaft comprises a second segment provided with optically detectable markings that allow the monitoring of the longitudinal and/or rotational displacement of the piston in regard to the cylinder.
Abstract translation: 提出了一种用于移动式输液泵装置的给药单元。 计量单元包括具有气缸的气缸泵和布置在气缸中的活塞。 活塞具有轴，其具有与气缸的螺纹部分相互作用的第一螺纹部分，并且可以相对于圆柱体围绕轴线旋转活塞，沿着圆柱体的纵向轴线移位。 此外，活塞允许相对或绝对地确定活塞相对于气缸的纵向和/或旋转位移。 在一个实施例中，活塞轴包括设置有光学可检测标记的第二段，其允许监测活塞相对于气缸的纵向和/或旋转位移。
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公开(公告)号：US08394051B2
公开(公告)日：2013-03-12
申请号：US12615338
申请日：2009-11-10
Applicant: Andreas Geipel
Inventor： Andreas Geipel
CPC classification number: G01L7/00 , A61M5/141 , A61M5/16854 , A61M2205/3386 , G01K5/28 , G01L11/00 , Y10T137/87265 , Y10T137/87338
Abstract: A device for detecting pressure and/or temperature changes in a fluid-channel and method thereof are disclosed. The device includes a main duct with an inlet and an outlet, a branch ductwork with a first branch end branching off the main duct downwards the inlet and with a second branch end discharging into the main duct upwards the outlet, and at least one dead-end channel with a first end that branches off the branch ductwork and a second closed end. The dead-end channel is adapted to trap a gas bubble within the dead-end channel when the device is primed or filled with a liquid fluid, wherein the gas bubble changes its size or position if a change in pressure or temperature occurs in the device.
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公开(公告)号：US20140039392A1
公开(公告)日：2014-02-06
申请号：US14049480
申请日：2013-10-09
Applicant: Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
Inventor： Andreas Geipel , Joerg Dogwiler , Ulrich Haueter , Simon Scheurer , Rudolf Zihlmann , David Teutsch , Florian Kuehni , Reto Schaltegger
Abstract: An infusion pump device and method for filling a fluidic system of the infusion pump with liquid medicament prior to infusion operation is presented. A control unit causes the infusion pump to: (a) bring a pump to an initial state; (b) switch a valve to a first state connecting a secondary reservoir to a first conduit and a primary reservoir; (c) retrieve medicament from the primary reservoir; (d) switch the valve to a second state connecting the secondary reservoir to a second downstream conduit; (e) expel the secondary reservoir contents into the second downstream conduit; (f) switch the valve to the first state; (g) retrieve the primary reservoir medicament; (h) switch the valve to the second state; and (i) expel the secondary reservoir contents into the second downstream conduit by shifting a piston to the initial position.
Abstract translation: 提出一种输液泵装置和方法，用于在输注操作之前用液体药物填充输液泵的流体系统。 控制单元使输液泵：（a）使泵进入初始状态; （b）将阀切换到将次级储存器连接到第一管道和主储存器的第一状态; （c）从初级贮存器回收药物; （d）将所述阀切换到将所述辅助容器连接到第二下游导管的第二状态; （e）将第二储存器内容物排出到第二下游导管中; （f）将阀门切换到第一状态; （g）检索主要储存药剂; （h）将阀门切换到第二状态; 和（i）通过将活塞移动到初始位置将次级容器内容物排出到第二下游管道中。
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