公开(公告)号：US06192265B1

公开(公告)日：2001-02-20

申请号：US09039351

申请日：1998-03-13

申请人： Ingwer Carlsen ,  Johannes J. Van Vaals ,  Volker Rasche ,  Michael Grass

发明人： Ingwer Carlsen ,  Johannes J. Van Vaals ,  Volker Rasche ,  Michael Grass

IPC分类号： A61B505

CPC分类号： G06T11/005

摘要： The invention relates to an image processing method for improving the signal-to-noise ratio for a series of MR images or CT images which are based on the projection-reconstruction method. First the pixels which reproduce the same sub-structure in the projection images are determined in the one-dimensional projection images constituting the two-dimensional MR or CT images. The image values of these pixels are subjected to noise filtering. Two-dimensional MR images or CT images are reconstructed from the noise filtered one-dimensional projection images.

摘要翻译： 本发明涉及一种用于改善基于投影重建方法的一系列MR图像或CT图像的信噪比的图像处理方法。 首先，在构成二维MR或CT图像的一维投影图像中确定在投影图像中再现相同子结构的像素。 对这些像素的图像值进行噪声滤波。 从噪声滤波的一维投影图像重建二维MR图像或CT图像。

公开(公告)号：US20050185831A1

公开(公告)日：2005-08-25

申请号：US10516151

申请日：2003-05-21

申请人： Volker Rasche ,  Babak Movassaghi ,  Michael Grass

发明人： Volker Rasche ,  Babak Movassaghi ,  Michael Grass

IPC分类号： A61B6/02 ,  A61B6/00 ,  G06T7/00 ,  G06T7/60 ,  G06K9/00

CPC分类号： G06T7/60 ,  G06T7/593 ,  G06T2207/30101 ,  Y10S128/922

摘要： A method is provided for analysis of a multi-dimensional structure which includes a tubular structure from two-dimensional datasets for respective pre-determined projection directions. A pair of corresponding initial projected centre points of the tubular structure is identified in two respective initial and further two-dimensional datasets. Projected edges of the tubular structure in said initial two-dimensional datasets and in said further two-dimensional dataset near the respective projected centre points are identified. A local size of the tubular strucwur is derived at the three-dimensional spatial position of the centre point of the tubular structure from said projected edges and the predetermined projection directions.

摘要翻译： 提供了一种用于分析多维结构的方法，其包括用于各个预定投影方向的二维数据集的管状结构。 在两个相应的初始和进一步的二维数据集中识别管状结构的一对相应的初始投影中心点。 识别所述初始二维数据集中的所述管状结构的投影边缘和在相应的投影中心点附近的所述另外的二维数据集中。 在管状结构的中心点从所述投影边缘和预定投影方向的三维空间位置导出管状结构的局部尺寸。

公开(公告)号：US07706589B2

公开(公告)日：2010-04-27

申请号：US10516151

申请日：2003-05-21

申请人： Volker Rasche ,  Babak Movassaghi ,  Michael Grass

发明人： Volker Rasche ,  Babak Movassaghi ,  Michael Grass

IPC分类号： G06K9/00

CPC分类号： G06T7/60 ,  G06T7/593 ,  G06T2207/30101 ,  Y10S128/922

摘要： A method is provided for analysis of a multi-dimensional structure which includes a tubular structure from two-dimensional datasets for respective pre-determined projection directions. A pair of corresponding initial projected centre points of the tubular structure is identified in two respective initial and further two-dimensional datasets. Projected edges of the tubular structure in said initial two-dimensional datasets and in said further two-dimensional dataset near the respective projected centre points are identified. A local size of the tubular structure is derived at the three-dimensional spatial position of the centre point of the tubular structure from said projected edges and the predetermined projection directions.

摘要翻译： 提供了一种用于分析多维结构的方法，其包括用于各个预定投影方向的二维数据集的管状结构。 在两个相应的初始和进一步的二维数据集中识别管状结构的一对相应的初始投影中心点。 识别所述初始二维数据集中的所述管状结构的投影边缘和在相应的投影中心点附近的所述另外的二维数据集中。 在管状结构的中心点从所述投影边缘和预定投影方向的三维空间位置导出管状结构的局部尺寸。

公开(公告)号：US20080037700A1

公开(公告)日：2008-02-14

申请号：US11570778

申请日：2005-06-24

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： A61B6/03

CPC分类号： G06T11/005 ,  A61B6/027 ,  G06T2211/404 ,  G06T2211/412 ,  G06T2211/416

摘要： The invention relates to an examination apparatus and a method for perfusion studies in a patient (1). According to the method, a rotational X-ray device (10) is moved on a closed, preferably non-planar trajectory (T) while continuously generating projections of the patient (1) after the injection of a contrast agent with an injection device (20). The projections are used by a data processing system (30) in a sliding window technique to reconstruct three-dimensional images of the body volume. The resulting sequence of 3D images may be displayed on a monitor (31) to reveal the desired information about the perfusion process.

摘要翻译： 本发明涉及一种用于患者（1）中的灌注研究的检查装置和方法。 根据该方法，旋转X射线装置（10）在闭合的，优选非平面的轨迹（T）上移动，同时在用注射装置注射造影剂之后连续产生患者（1）的突起 20）。 数据处理系统（30）在滑动窗口技术中使用投影来重建身体体积的三维图像。 所得到的3D图像序列可以显示在监视器（31）上，以显示关于灌注过程的期望信息。

公开(公告)号：US07277565B2

公开(公告)日：2007-10-02

申请号：US10481808

申请日：2002-06-13

申请人： Volker Rasche ,  Michael Grass

发明人： Volker Rasche ,  Michael Grass

IPC分类号： G06K9/00

CPC分类号： G06T11/005 ,  G06T2211/412

摘要： The invention relates to a method of reconstructing a high-resolution 3D image (G) of an examination zone of a patient from a 3D image data set (D) of the examination zone, the examination zone being subject to a periodic motion which is measured, in parallel with the acquisition of the 3D image data set (D), as a motion signal (E) which represents the periodic motion. In order to enable the formation of high-resolution 3D images having an enhanced image quality, the invention proposes a method of this kind which includes the following steps: a) reconstructing a number of low-resolution 3D images (I) from the 3D image data set (D), the low-resolution 3D images (I) being reconstructed from 3D image data of the 3D image data set (D) which has been acquired during different phases of motion of the periodic motion, b) determining motion information (B) of at least one sub-zone (A) of the examination zone during the different phases of motion by means of the low-resolution 3D images (I), c) selecting a temporal reconstruction window (T) in which the motion of the at least one sub-zone (A) is below a predetermined level, d) reconstructing a high-resolution sub-image (K) for the at least one sub-zone (A) from 3D image data (D) lying in the temporal reconstruction window (T) selected for the sub-zone (A), and e) forming the desired 3D image (G) from the at least one sub-image (K), the zones of the 3D image (G) which are not reconstructed as sub-images then being reconstructed from the 3D image data so as to be combined with the at least one sub-image (K).

摘要翻译： 本发明涉及从检查区域的3D图像数据集（D）重建患者检查区域的高分辨率3D图像（G）的方法，检查区域经受测量的周期性运动 与3D图像数据集（D）的获取并行，作为表示周期性运动的运动信号（E）。 为了能够形成具有增强图像质量的高分辨率3D图像，本发明提出了一种这样的方法，其包括以下步骤：a）从3D图像重建多个低分辨率3D图像（I） 数据组（D），从在周期运动的不同运动阶段获取的3D图像数据组（D）的3D图像数据重建低分辨率3D图像（I），b）确定运动信息（ B）通过低分辨率3D图像（I）在不同运动阶段期间的检查区域的至少一个子区域（A），c）选择时间重建窗口（T），其中运动 所述至少一个子区域（A）低于预定水平，d）从位于所述至少一个子区域（A）的3D图像数据（D）重建所述至少一个子区域（A）的高分辨率子图像（K） 对于子区域（A）选择的时间重建窗口（T），以及e）从at1形成期望的3D图像（G） 东一个子图像（K），未被重建为子图像的3D图像（G）的区域然后从3D图像数据重建，以便与至少一个子图像（K）组合， 。

公开(公告)号：US20060293579A1

公开(公告)日：2006-12-28

申请号：US10553770

申请日：2004-04-21

申请人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

发明人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

IPC分类号： A61B5/05 ,  A61B6/00

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/504

摘要： The invention relates to an X-ray imaging device for visualizing the blood flow in a coronary vascular tree of a patient. According to the invention a first set (1) of X-ray projection images of the vascular tree is recorded during various phases of the heart cycle with simultaneous recording of the ECG (2) of the patient. By means of a suitable program control, computer means (17) of the device according to the invention a reconstruction then follows of the three-dimensional structure of the vascular tree during the various phases of the heart cycle. The invention proposes, to determine the time-dependent concentration of contrast agent within the reconstructed three-dimensional structure of the vascular tree, that local image areas within the X-ray projection images of the second set (6) assigned to individual vascular segments (5, 8) are located in accordance with the spatial positions of the vascular segments (5, 8) in the relevant phase of the heart cycle. The concentration of contrast agent in the area of the vascular segments (5, 8) is then determined by evaluation of the X-ray absorption within the local image areas found.

摘要翻译： 本发明涉及用于使患者的冠状动脉血管树中的血流可视化的X射线成像装置。 根据本发明，在心脏周期的各个阶段记录血管树的X射线投影图像的第一组（1），同时记录患者的ECG（2）。 通过合适的程序控制，根据本发明的装置的计算机装置（17）在心脏周期的各个阶段期间重建血管树的三维结构。 本发明提出，为了确定造影剂在血管树的重建三维结构内的时间依赖性浓度，将第二组（6）的X射线投影图像内的局部图像区域分配给各个血管节段 5,8）根据心脏周期的相关阶段中血管段（5,8）的空间位置来定位。 然后通过评估所发现的局部图像区域内的X射线吸收来确定血管片段（5,8）区域中造影剂的浓度。

公开(公告)号：US06865248B1

公开(公告)日：2005-03-08

申请号：US09668938

申请日：2000-09-25

申请人： Volker Rasche ,  Michael Grass

发明人： Volker Rasche ,  Michael Grass

IPC分类号： A61B6/00 ,  A61B6/02 ,  G01N23/00

CPC分类号： A61B6/541

摘要： The invention relates to a method of and a device for the formation of a three-dimensional image data set of a periodically moving body organ (11) of a patient (5) by means of an X-ray device (1) which includes an X-ray source and an X-ray detector (3), a motion signal (H, B) which is related to the periodic motion of the body organ (11) being measured simultaneously with the acquisition of the projection data sets (D0, D1, . . . , D16). In order to improve such a method or such a device, notably in order to improve the construction and to reduce the time required for data processing while keeping the radiation dose for the patient as small as possible and while ensuring an as high as possible image quality, the invention proposes to acquire the projection data sets (D0, D1, . . . , D16) necessary for the formation of the three-dimensional image data set successively from different X-ray positions (p0, p1, . . . , p16) which are situated in one plane, to control the X-ray device by means of the motion signal (H, B) in such a manner that a projection data set (D0, D1, . . . , D16) is acquired during a low-motion phase of the body organ (11) in each X-ray position (p0, p1, p16) required for the formation of the three-dimensional image data set, and to use the projection data sets (D0, D1, . . . , D16) acquired during the low-motion phase for the formation of the three-dimensional image data set.

摘要翻译： 本发明涉及一种用于通过X射线装置（1）形成患者（5）的周期性运动的身体器官（11）的三维图像数据集的方法和装置，所述X射线装置包括： X射线源和X射线检测器（3），与获取投影数据组（D0，...）同时测量与身体器官（11）的周期运动相关的运动信号（H，B） D1，...，D16）。 为了改进这种方法或这种装置，特别是为了改善结构并减少数据处理所需的时间，同时保持患者的辐射剂量尽可能小并且同时确保尽可能高的图像质量 本发明提出从不同的X射线位置（p0，p1，...，p16）连续地获取形成三维图像数据所需的投影数据集（D0，D1，... D16） ），以通过运动信号（H，B）以这样的方式控制X射线装置，使得在一个平面内获取投影数据组（D0，D1，...，D16） 在形成三维图像数据集所需的每个X射线位置（p0，p1，p16）中的身体器官（11）的低运动相位，并使用投影数据组（D0，D1，...）。 ...，D16）在形成三维图像数据集的低运动阶段期间获得。

公开(公告)号：US20080218510A1

公开(公告)日：2008-09-11

申请号：US11997340

申请日：2006-07-12

申请人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

发明人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC分类号： G06T15/00

CPC分类号： G06T11/005 ,  G06T2211/412

摘要： A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

摘要翻译： 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US20070025507A1

公开(公告)日：2007-02-01

申请号：US10571821

申请日：2004-09-16

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： G01N23/04

CPC分类号： G06T11/005 ,  A61B6/027

摘要： The invention relates to an imaging process with a beam source attached at a first end of an holder device, and with a detector unit attached to a second end of the holder device. The holder device is moved so that the beam source is guided about an examination area along a non-circular trajectory, where the beams emitted by the beam source pass through the examination area. The detector unit acquires measurement values which depend on the intensity of the beams on the far side of the examination area. From these measurement values using a filtered back projection an image of the examination area can be reconstructed, where each measurement value is filtered along a filter line which runs parallel to the tangent of the trajectory at the respective position of the beam source.

摘要翻译： 本发明涉及一种成像过程，其中束源连接在保持器装置的第一端，并且检测器单元附接到保持器装置的第二端。 保持装置被移动，使得光束源沿着非圆形轨迹围绕检查区域被引导，其中由光束源发射的光束通过检查区域。 检测器单元获取取决于在检查区域的远侧的光束的强度的测量值。 使用滤波反投影的这些测量值可以重建检查区域的图像，其中每个测量值沿着平行于光束源的相应位置处的轨迹的切线延伸的滤波器线被滤波。

公开(公告)号：US06823204B2

公开(公告)日：2004-11-23

申请号：US10221240

申请日：2002-09-09

申请人： Michael Grass ,  Holger Schmitt ,  Volker Rasche

发明人： Michael Grass ,  Holger Schmitt ,  Volker Rasche

IPC分类号： A61B505

CPC分类号： A61B6/481 ,  A61B6/4014 ,  A61B6/504 ,  A61B6/507 ,  G06T17/00

摘要： The invention relates to a method of imaging a vascular tree that yields additional information concerning the vascular tree. To this end, a sequence of clusters is determined from spatially coherent voxels in the three-dimensional image of the vascular tree, the sequence of said clusters corresponding to the flow direction of the blood or the contrast medium in said vascular tree.

摘要翻译： 本发明涉及一种对血管树进行成像的方法，其产生关于血管树的附加信息。 为此，从血管树的三维图像中的空间相干体素确定簇序列，所述簇的序列对应于所述血管树中的血液或造影剂的流动方向。