公开(公告)号：US20220033829A1

公开(公告)日：2022-02-03

申请号：US17387780

申请日：2021-07-28

Applicant: Inscripta, Inc.

Inventor： Tyson Shepherd ,  Andrew Garst ,  Daniel Held ,  Eric Abbate

IPC: C12N15/63 ,  C12N9/22 ,  C12N15/11

Abstract: The present disclosure relates to compositions, methods, modules and automated integrated instrumentation for using sets of short, curated peptide barcodes to track nucleic acid-guided edits and the translated proteins that result from the edits as well as to create in vitro pathways.

公开(公告)号：US20230086008A1

公开(公告)日：2023-03-23

申请号：US17683692

申请日：2022-03-01

Applicant: Inscripta, Inc.

Inventor： Tyson Shepherd

IPC: C12Q1/689 ,  C12N15/10 ,  G16B20/20

Abstract: The present disclosure relates to cell populations and systems for detection of compounds in an environment. Specifically the disclosure relates to methods for generating reproducible genome-wide edited populations of microbes that display novel, defined, and reproducible phenotypes when exposed to one or more chemicals. In some applications, such phenotypes are read out by barcode amplicon and compared against population fingerprints. In other applications digital information is stored in such populations of microorganisms. The digital information can be retrieved from the microorganisms with Boolean logic.

公开(公告)号：US20220380825A1

公开(公告)日：2022-12-01

申请号：US17683343

申请日：2022-02-28

Applicant: Inscripta, Inc.

Inventor： Tyson Shepherd ,  Steve Federowicz ,  Dan Held

IPC: C12P21/00 ,  C12N15/10 ,  C12N1/20 ,  C12N15/70

Abstract: The present disclosure is directed to devices, instruments, and methods, including automated methods, for enhanced production and efficient screening of biosynthesized antibiotics. More particularly, the present disclosure provides for accelerated biosynthesis and screening on a single-cell scale.