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    Gelatin Sponge Comprising an Active Ingredient, Its Preparation and Use
    3.
    发明申请
    Gelatin Sponge Comprising an Active Ingredient, Its Preparation and Use 有权
    明胶海绵包含活性成分，其制备和用途

    公开(公告)号：US20140120151A1

    公开(公告)日：2014-05-01

    申请号：US13847898

    申请日：2013-03-20

    申请人： Israel Nur ,  Liliana Bar ,  Guy Tomer ,  Eyal Sheetrit

    发明人： Israel Nur ,  Liliana Bar ,  Guy Tomer ,  Eyal Sheetrit

    IPC分类号： A61K9/70 ,  A61K38/48

    CPC分类号： A61L15/425 ,  A61K9/70 ,  A61K38/4833 ,  A61L15/32 ,  A61L15/325 ,  A61L15/44 ,  A61L2300/252 ,  A61L2300/418 ,  A61L2300/606 ,  A61L2400/04

    摘要： The present invention is directed to a method for manufacturing a cross-linked gelatin sponge having a surface by providing a cross-linked gelatin sponge, wetting the surface of the sponge by applying a sufficient amount of liquid comprising a protein or peptide active ingredient, wherein a sufficient amount of liquid is one that retains the flexibility of the sponge even after drying. The sponge is then dried the sponge to obtain a flexible, dry and ready to use cross linked gelatin sponge having a layer of protein or peptide active ingredient on the surface thereof.

    摘要翻译： 本发明涉及通过提供交联明胶海绵来制造具有表面的交联明胶海绵的方法，通过施加足量的包含蛋白质或肽活性成分的液体来润湿海绵的表面，其中 足够量的液体即使在干燥后也保持海绵的柔韧性。 然后将海绵干燥成海绵，以获得在其表面上具有蛋白质或肽活性成分层的柔性，干燥且准备使用的交联明胶海绵。