摘要:
This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.
摘要:
This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.
摘要:
A mass and heat exchanger includes at least one first substrate with a surface for supporting a continuous flow of a liquid thereon that either absorbs, desorbs, evaporates or condenses one or more gaseous species from or to a surrounding gas; and at least one second substrate operatively associated with the first substrate. The second substrate includes a surface for supporting the continuous flow of the liquid thereon and is adapted to carry a heat exchange fluid therethrough, wherein heat transfer occurs between the liquid and the heat exchange fluid.
摘要:
Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.
摘要:
A nucleic acid probe assay which combines nucleic acid amplification with solution hybridization using capture and reporter probes followed by or simultaneously with immobilization on a solid support is provided. An assay sensitivity equal to 5 copies of HIV I DNA was achieved.
摘要翻译:提供了一种核酸探针测定法,其使用捕获和报道探针将核酸扩增与溶液杂交结合在一起,同时固定在固体支持物上。 获得等于5拷贝的HIV I DNA的测定灵敏度。
摘要:
Envelope viruses (e.g. Newcastle disease virus (NDV)) are formulated for storage at moderately cold temperatures (e.g. −20° C.). The formulation is an aqueous solution containing the enveloped virus at a concentration of from 106 PFU/mL to 1012 PFU/mL; and a non-reducing saccharide (e.g. sucrose). When the non-reducing saccharide is a disaccharide it is present in the solution at a concentration of from 5% (w/v) to 50% (w/v), and when it is a monosaccharide it is present in the solution at a concentration of from 2.5% (w/v) to 25% (w/v). The solution has an osmotic pressure of about 250 mOs or higher, and has a pH of from 5 to 10.
摘要:
A method of treating a human subject with cancer is disclosed. A pharmaceutical composition is administered to the subject, the pharmaceutical composition comprising human leukocytes and a replication-competent oncolytic virus in suspension in a physiologically acceptable solution. Alternatively the pharmaceutical composition comprises human leukocytes or platelets infected with an oncolytic virus.
摘要:
According to one embodiment of the present invention an electrolyte sheet includes a body of varied thickness, the electrolyte sheet having a textured surface with multiple protruding features. The protruding features form an undercut angle with respect to the normal of the electrolyte sheet, the undercut angle being more than 0 degrees and less than 15 degrees.
摘要:
A circuit breaker contact assembly includes a line conductor having a folded back fixed contact end, a fixed contact mounted on the contact end, and a movable contact arm having an inner edge and first and second ends. A movable contact is mounted on the first end. The movable contact arm is pivotable about the second end between a closed position in which the inner edge extends adjacent the contact end with the movable contact in contact with the fixed contact to form a reverse current loop, and an open position in which the movable contact is pivoted away from the fixed contact. The contact arm includes a first inner longitudinal member extending along the inner edge and a second outer longitudinal member. The first inner longitudinal member has a higher electrical conductivity than the second outer longitudinal member, which has a higher shear strength and a lower specific density.