-
公开(公告)号:US20220213542A1
公开(公告)日:2022-07-07
申请号:US17600593
申请日:2020-04-02
申请人: Jingyue Ju , Shiv Kumar , James Russo , Xiaoxu Li , Steffen Jockusch , Minchen Chien , Chuanjuan Tao
发明人: Jingyue Ju , Shiv Kumar , James Russo , Xiaoxu Li , Steffen Jockusch , Minchen Chien , Chuanjuan Tao
IPC分类号: C12Q1/6869 , C12Q1/6848
摘要: The invention provides nucleotide analogues and methods of use thereof for sequencing by synthesis using energy transfer dye pairs.
-
2.
公开(公告)号:US20220177959A1
公开(公告)日:2022-06-09
申请号:US17436513
申请日:2020-03-05
申请人: Jingyue Ju , Carl W. Fuller , Shiv Kumar , Sergey Kalachikov , Xiaoxu Li , Irina Morozova , James Russo , Steffen Jockusch
发明人: Jingyue Ju , Carl W. Fuller , Shiv Kumar , Sergey Kalachikov , Xiaoxu Li , Irina Morozova , James Russo , Steffen Jockusch
IPC分类号: C12Q1/6869
摘要: Disclosed herein are highly accurate approaches for single molecule electronic nanopore-based SBS.
-
公开(公告)号:US20200063194A1
公开(公告)日:2020-02-27
申请号:US16499997
申请日:2018-04-03
申请人: Jingyue Ju , Timothy H. Bestor , James J. Russo , Steffen Jockusch , Xiaoxu Li
发明人: Jingyue Ju , Timothy H. Bestor , James J. Russo , Steffen Jockusch , Xiaoxu Li
IPC分类号: C12Q1/6827 , C12N9/10
摘要: The subject invention provides a method of determining whether a cytosine at a predefined position within a single strand of a double-stranded DNA of known sequence is hydroxymethylated.The invention also provides a method of determining whether a cytosine at a predefined position within a single strand of a double-stranded DNA of known sequence is unmethylated.The invention further provides a method of determining whether a cytosine at a predefined position within a single strand of a double-stranded DNA of known sequence is methylated but not hydroxymethylated.The invention also provides a method of determining whether a cytosine present at a predefined position within a single strand of a double-stranded DNA of known sequence, and within a CpG site, is unmethylated.
-
-