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1.发明申请公开(公告)号：US20200376167A1
公开(公告)日：2020-12-03
申请号：US16875107
申请日：2020-05-15
Applicant: Korea University Research and Business Foundation , Korea Institute of Science and Technology
Inventor： Jong Woong Park , Young Mee Jung , Soo Hyun Kim , Justin Jihong Chung
Abstract: The present invention relates to a method for preparing of a nerve conduit using bio-printing technology and a nerve conduit prepared by the same, and it can easily prepare a nerve conduit by simulating a nerve bundle and nerve tissue, and the like, by three-dimensionally printing bio-ink comprising a neuronal regeneration material on one side of a porous polymer scaffold.
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公开(公告)号：US11920118B2
公开(公告)日：2024-03-05
申请号：US17081723
申请日：2020-10-27
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Young Mee Jung , Soo Hyun Kim , Justin Jihong Chung , Jin Yoo , Tae Hee Kim
IPC: C12M1/00
Abstract: Provided are a method for fabricating a highly elastic porous polymer membrane, a method for manufacturing a cell culture system using a porous polymer membrane fabricated by the fabrication method, and a cell culture system manufactured by the manufacturing method. The porous polymer membrane can be fabricated by spin coating a mixture solution containing a biodegradable elastomeric polymer and a water-soluble moisture absorbent in an optimum ratio while maintaining a high relative humidity. The porous polymer membrane has a uniform thickness and a uniform pore size and is highly elastic. In addition, the thickness and pore size of the porous polymer membrane can be controlled. The porous polymer membrane can induce active cell-cell interaction during cell co-culture due to its high porosity. The porous polymer membrane enables control over cell alignment or array due to its high biocompatibility and elasticity. The porous polymer membrane can be utilized in a platform for inducing stem cell differentiation, a lab-on-a-chip, a synthetic skin simulant platform, etc.
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公开(公告)号：US11607474B2
公开(公告)日：2023-03-21
申请号：US16875107
申请日：2020-05-15
Applicant: Korea University Research and Business Foundation , Korea Institute of Science and Technology
Inventor： Jong Woong Park , Young Mee Jung , Soo Hyun Kim , Justin Jihong Chung
Abstract: The present invention relates to a method for preparing of a nerve conduit using bio-printing technology and a nerve conduit prepared by the same, and it can easily prepare a nerve conduit by simulating a nerve bundle and nerve tissue, and the like, by three-dimensionally printing bio-ink comprising a neuronal regeneration material on one side of a porous polymer scaffold.
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公开(公告)号：US11434570B2
公开(公告)日：2022-09-06
申请号：US17338110
申请日：2021-06-03
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hojeong Jeon , Seung Hoon Um , Jae Ho Park , Justin Jihong Chung , Hyunseon Seo , Hyung-Seop Han , Yu Chan Kim , Myoung-Ryul Ok , Hyun Kwang Seok
IPC: C23C26/00 , B23K26/352 , B23K26/122 , C01B25/32
Abstract: Provided is a method of forming an apatite coating, the method including immersing a substrate in an apatite-forming precursor solution including Ca2+ ions and PO43− ions, emitting a laser beam onto a surface of the substrate immersed in the precursor solution, and forming an apatite coating in a region exposed to the laser beam, wherein an output power of the laser beam is set within a range enabling the surface of the substrate to be melted.
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