摘要:
Novel polypeptides which have an excellent angiogenesis-inducing activity and an excellent antibacterial activity and medical uses thereof are disclosed. The amino acid sequences of the novel polypeptides are shown in any one of SEQ ID NOs:1 to 6. These polypeptides have angiogenesis-inducing and antibacterial activities. Such polypeptides are useful for the prevention, amelioration or treatment of skin wounds caused by a cut wound, surgical wound, erosion, burn, decubitus, intractable wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease or arteriosclerosis obliteran, and for the prevention, amelioration or treatment of bacterial infection in such skin wounds, and the like.
摘要翻译:公开了具有优异的血管发生诱导活性和优异的抗菌活性的新型多肽及其医疗用途。 新型多肽的氨基酸序列显示在SEQ ID NO:1至6中的任一个中。这些多肽具有血管发生诱导和抗菌活性。 这样的多肽可用于预防,改善或治疗由切口伤口,手术伤口,侵蚀,烧伤,褥疮,难治性伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病或闭塞性动脉硬化引起的皮肤伤口,以及 预防,改善或治疗这些皮肤伤口中的细菌感染等。
摘要:
A novel polypeptide which has an excellent angiogenesis-inducing activity and an excellent antibacterial activity, and a novel angiogenesis-inducing agent which contains the polypeptide as an effective ingredient or a novel agent for treating a wound(s) which contains the polypeptide as an effective ingredient are disclosed. The polypeptide of the present invention is a polypeptide whose amino acid sequence is shown in any one of SEQ ID NOs:1 to 6, 8 and 10. The angiogenesis-inducing agent which contains the polypeptide of the present invention as an effective ingredient is useful for the prevention, amelioration or treatment of a disease such as a burns, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliteran.
摘要翻译:具有优异的血管发生诱导活性和优异的抗菌活性的新型多肽和含有多肽作为有效成分的新型血管生成诱导剂或用于治疗伤口的新型药剂,其含有多肽作为有效成分 成分被公开。 本发明的多肽是其氨基酸序列示于SEQ ID NO:1-6,8,10中的任一个中的多肽。含有本发明多肽作为有效成分的血管生成诱导剂是有用的 用于预防,改善或治疗诸如烧伤,褥疮,伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病和闭塞性动脉硬化的疾病。
摘要:
A novel polypeptide, and an antibacterial agent, antifungal agent and/or antiseptic containing as an effective ingredient the polypeptide are disclosed. The polypeptide of this invention has an amino acid sequence shown in SEQ ID NOs:1 to 12 and 13 to 31. This antibacterial agent, antifungal agent and/or antiseptic is useful for the prevention, amelioration or treatment of diseases such as burn, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliterans, cellulitis, acute lymphangitis, lymphadenitis, erysipelas, skin abscess, necrotizing subcutaneous infection, staphylococcal scalded skin syndrome (SSSS), folliculitis, facial furuncle, suppurative hidradenitis, carbuncle, infectious paronychia, erythrasma and severe infection (sepsis).
摘要翻译:公开了一种新颖的多肽,以及含有该多肽的有效成分的抗菌剂,抗真菌剂和/或防腐剂。 本发明的多肽具有SEQ ID NO:1至12和13至31所示的氨基酸序列。该抗菌剂,抗真菌剂和/或防腐剂可用于预防,改善或治疗诸如烧伤,褥疮 伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病和闭塞性闭塞性动脉硬化症,蜂窝织炎,急性淋巴管炎,淋巴结炎,丹毒,皮肤脓肿,坏死性皮下感染,葡萄球菌性烫伤皮肤综合征(SSSS),毛囊炎,面部le疮,化脓性头痛 ,carb,感染性甲沟炎,红斑狼疮和严重感染(败血症)。
摘要:
A novel polypeptide which has an excellent angiogenesis-inducing activity and an excellent antibacterial activity, and a novel angiogenesis-inducing agent which contains the polypeptide as an effective ingredient or a novel agent for treating a wound(s) which contains the polypeptide as an effective ingredient are disclosed. The polypeptide of the present invention is a polypeptide whose amino acid sequence is shown in any one of SEQ ID NOs:1 to 6, 8 and 10. The angiogenesis-inducing agent which contains the polypeptide of the present invention as an effective ingredient is useful for the prevention, amelioration or treatment of a disease such as a burns, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliteran.
摘要翻译:具有优异的血管发生诱导活性和优异的抗菌活性的新型多肽和含有多肽作为有效成分的新型血管生成诱导剂或用于治疗伤口的新型药剂,其含有多肽作为有效成分 成分被公开。 本发明的多肽是其氨基酸序列示于SEQ ID NO:1-6,8,10中的任一个中的多肽。含有本发明多肽作为有效成分的血管生成诱导剂是有用的 用于预防,改善或治疗诸如烧伤,褥疮,伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病和闭塞性动脉硬化的疾病。
摘要:
A novel polypeptide, and an antibacterial agent, antifungal agent and/or antiseptic containing as an effective ingredient the polypeptide are disclosed. The polypeptide of this invention has an amino acid sequence shown in SEQ ID NOs:1 to 12 and 13 to 31. This antibacterial agent, antifungal agent and/or antiseptic is useful for the prevention, amelioration or treatment of diseases such as burn, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliterans, cellulitis, acute lymphangitis, lymphadenitis, erysipelas, skin abscess, necrotizing subcutaneous infection, staphylococcal scalded skin syndrome (SSSS), folliculitis, facial furuncle, suppurative hidradenitis, carbuncle, infectious paronychia, erythrasma and severe infection (sepsis).
摘要翻译:公开了一种新颖的多肽,以及含有该多肽的有效成分的抗菌剂,抗真菌剂和/或防腐剂。 本发明的多肽具有SEQ ID NO:1至12和13至31所示的氨基酸序列。该抗菌剂,抗真菌剂和/或防腐剂可用于预防,改善或治疗诸如烧伤,褥疮 伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病和闭塞性闭塞性动脉硬化症,蜂窝织炎,急性淋巴管炎,淋巴结炎,丹毒,皮肤脓肿,坏死性皮下感染,葡萄球菌性烫伤皮肤综合征(SSSS),毛囊炎,面部le疮,化脓性头痛 ,carb,感染性甲沟炎,红斑狼疮和严重感染(败血症)。
摘要:
Novel polypeptides which have an excellent angiogenesis-inducing activity and an excellent antibacterial activity and medical uses thereof are disclosed. The amino acid sequences of the novel polypeptides are shown in any one of SEQ ID NOs:1 to 6. These polypeptides have angiogenesis-inducing and antibacterial activities. Such polypeptides are useful for the prevention, amelioration or treatment of skin wounds caused by a cut wound, surgical wound, erosion, burn, decubitus, intractable wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease or arteriosclerosis obliteran, and for the prevention, amelioration or treatment of bacterial infection in such skin wounds, and the like.
摘要翻译:公开了具有优异的血管发生诱导活性和优异的抗菌活性的新型多肽及其医疗用途。 新型多肽的氨基酸序列显示在SEQ ID NO:1至6中的任一个中。这些多肽具有血管发生诱导和抗菌活性。 这样的多肽可用于预防,改善或治疗由切口伤口,手术伤口,侵蚀,烧伤,褥疮,难治性伤口,皮肤溃疡,腿部溃疡,糖尿病性溃疡,闭塞性动脉疾病或闭塞性动脉硬化引起的皮肤伤口,以及 预防,改善或治疗这些皮肤伤口中的细菌感染等。