公开(公告)号：US11357798B2

公开(公告)日：2022-06-14

申请号：US15749766

申请日：2016-08-03

Applicant: OSAKA UNIVERSITY ,  ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kohji Nishida ,  Ryuuhei Hayashi ,  Yoichi Honma ,  Toru Okubo ,  Shun Shibata

IPC: A61K35/28 ,  A61P27/02 ,  C12N5/0775 ,  C12N5/00 ,  C12Q1/02 ,  A61K35/12

Abstract: The present invention relates to mesenchymal stem cell-derived microparticles having activity that promotes the growth of corneal epithelial stem cells and/or corneal epithelial cells, activity that maintains corneal epithelial stem cells in an undifferentiated state or promotes the formation of colonies thereby, and function that protects corneal epithelium.