公开(公告)号：US11209394B2

公开(公告)日：2021-12-28

申请号：US16319410

申请日：2017-07-26

Applicant: QORVO US, INC.

Inventor： Thayne L. Edwards ,  Florian Bell ,  Matthew Ryder ,  Bruce Murdock

IPC: G01N29/02 ,  G01N29/036 ,  G01N29/22 ,  G01N29/24 ,  G01N29/32 ,  B01L3/00 ,  H03H9/17

Abstract: A cartridge for sample handling and sensing includes (i) a sample port; (ii) a first fluid port connected to the sample reservoir in the distal region via a first fluid channel; and (iii) a second fluid port connected to the sample reservoir via a second fluid channel. The cartridge includes (i) a sensor platform comprising a bulk acoustic wave (BAW) resonator and a fluid flow path comprising a sensing region extending across a sensing surface of the BAW resonator; and (ii) a fluid valve between the sample reservoir and the sensing region. A sample may be applied to the sample port; first volume of fluid may be injected through the first fluid port; and then a second volume of fluid may be injected through the second fluid port to drive the sample into the sensing region of the fluid flow path.

公开(公告)号：US20210138461A1

公开(公告)日：2021-05-13

申请号：US16319540

申请日：2017-08-02

Applicant: QORVO US, INC.

Inventor： Thayne L. Edwards ,  Florian Bell

IPC: B01L3/00

Abstract: A sampler for acquiring and transporting sample material may include a sampler body defining a sampling volume configured to hold the sample material. The sampler body may define a sample port that may be used as an entrance to collect the sample material and an exit to expel the sample material. The sample port may be configured to be operably connected to a fluidic channel of a cartridge. The sampler may also define a pump connection port configured to be operably connected to a pump. The pump may force the sample material out of the sampling volume through the sample port.

公开(公告)号：US20190234907A1

公开(公告)日：2019-08-01

申请号：US16319410

申请日：2017-07-26

Applicant: QORVO US, INC.

Inventor： Thayne L. Edwards ,  Florian Bell ,  Matthew Ryder ,  Bruce Murdock

IPC: G01N29/02 ,  G01N29/22 ,  G01N29/24 ,  G01N29/32 ,  G01N29/036 ,  B01L3/00

CPC classification number: G01N29/022 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/165 ,  B01L2400/0688 ,  B01L2400/088 ,  G01N29/02 ,  G01N29/036 ,  G01N29/22 ,  G01N29/222 ,  G01N29/2437 ,  G01N29/32 ,  G01N2291/014 ,  G01N2291/022 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/0426 ,  G01N2291/106 ,  H03H9/175

Abstract: A cartridge for sample handling and sensing includes a sample port connected to a sample reservoir having a proximal end, a proximal region adjacent the proximal end, and a distal end opposite of the proximal end. The cartridge also includes a first fluid port connected to the sample reservoir in the distal region via a first fluid channel; and a second fluid port connected to the sample reservoir in the proximal region via a second fluid channel. In addition, the cartridge includes a sensor platform comprising a bulk acoustic wave (BAW) resonator and a fluid flow path comprising a sensing region extending across a sensing surface of the BAW resonator. The cartridge further includes a fluid valve between the distal end of the sample reservoir and the sensing region. A sample may be applied to the sample port; first volume of fluid may be injected through the first fluid port; and then a second volume of fluid may be injected through the second fluid port to drive the sample into the sensing region of the fluid flow path.

公开(公告)号：US10974243B2

公开(公告)日：2021-04-13

申请号：US16319398

申请日：2017-07-26

Applicant: QORVO US, INC.

Inventor： Thayne L. Edwards

IPC: G01N27/447 ,  B01L3/00 ,  G01N29/02 ,  G01N29/036 ,  G01N29/22 ,  B03C5/00

Abstract: A sensor using electrophoresis may include a microfluidic channel and electrodes on opposite sides of the microfluidic channel to generate an electric field across, or normal to, the channel. The electric field may be used to drive charged particles of material, particularly material suspended in fluid in the microfluidic channel, toward or away from the one of the electrodes. The electric field may be modulated to allow material to continue flowing through the microfluidic channel, to remove non-target material, or to measure another target material.

公开(公告)号：US20190329255A1

公开(公告)日：2019-10-31

申请号：US16319398

申请日：2017-07-26

Applicant: QORVO US, INC.

Inventor： Thayne L. Edwards

IPC: B01L3/00 ,  G01N29/02 ,  G01N29/036 ,  G01N29/22 ,  G01N27/447

Abstract: A sensor using electrophoresis may include a microfluidic channel and electrodes on opposite sides of the microfluidic channel to generate an electric field across, or normal to, the channel. The electric field may be used to drive charged particles of material, particularly material suspended in fluid in the microfluidic channel, toward or away from the one of the electrodes. The electric field may be modulated to allow material to continue flowing through the microfluidic channel, to remove non-target material, or to measure another target material.