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公开(公告)号:US20170182038A1
公开(公告)日:2017-06-29
申请号:US14964057
申请日:2015-12-09
申请人: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
发明人: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
IPC分类号: A61K31/497 , A61K31/5355 , A61K31/4436 , A61K31/4433 , A61K31/44
CPC分类号: A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04
摘要: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
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公开(公告)号:US20170348312A1
公开(公告)日:2017-12-07
申请号:US15538348
申请日:2015-12-21
申请人: Ho Man CHAN , Xiang-Ju Justin GU , Ying HUANG , Ling LI , Yuan MI , Wei QI , Martin SENDZIK , Yongfeng SUN , Long WANG , Zhengtian YU , Hailong ZHANG , Ji Yue (Jeff) ZHANG , Man ZHANG , Qiong ZHANG , Kehao ZHAO
发明人: Ho Man CHAN , Xiang-Ju Justin GU , Ying HUANG , Ling LI , Yuan MI , Wei QI , Martin SENDZIK , Yongfeng SUN , Long WANG , Zhengtian YU , Hailong ZHANG , Ji Yue (Jeff) ZHANG , Man ZHANG , Qiong ZHANG , Kehao ZHAO
IPC分类号: A61K31/519 , A61K31/551 , A61K31/541 , C07D487/04 , A61K31/5377
CPC分类号: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06 , C07D487/04
摘要: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.
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公开(公告)号:US20150126490A1
公开(公告)日:2015-05-07
申请号:US14527328
申请日:2014-10-29
申请人: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Jeff Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
发明人: Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Jeff Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
IPC分类号: C07D498/04 , A61K31/497 , A61K45/06 , C07D401/04 , A61K31/4545 , C07D405/14 , A61K31/506 , C07D409/04 , A61K31/4436 , A61K31/5383 , C07D241/20 , A61K31/4965 , A61K31/4439 , C07D413/14 , A61K31/5377 , A61K31/553 , C07D405/04
CPC分类号: A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04
摘要: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
摘要翻译: 本发明提供式(I)的化合物或其盐; 和这些化合物的治疗用途。 本发明还提供包含这些化合物的药物组合物,以及包含这些化合物与治疗性助剂的组合物。
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公开(公告)号:US20220300823A1
公开(公告)日:2022-09-22
申请号:US17204670
申请日:2021-03-17
申请人: Hanwen LIANG , Peng DAI , Qiong ZHANG , Juwei LU
发明人: Hanwen LIANG , Peng DAI , Qiong ZHANG , Juwei LU
摘要: Methods, systems, and media for training deep neural networks for cross-domain few-shot classification are described. The methods comprise an encoder and a decoder of a deep neural network. The training of the autoencoder comprises two training stages. For each iteration in the first training stage, a batch of data samples from the source dataset are sampled and fed to the encoder to generate a plurality of source feature maps, then determining a first training stage loss, which updates the autoencoder's parameters. For each iteration in the second training stage, the novel dataset is split into a support set and a query set. The support set is fed to the encoder to determine a prototype for each class label. The query set is also fed to the encoder to calculate a query set metric classification loss. The query set metric classification loss updates the autoencoder's parameters.
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公开(公告)号:US20140052419A1
公开(公告)日:2014-02-20
申请号:US13585663
申请日:2012-08-14
申请人: Xi WANG , Qiong ZHANG , Paparao PALACHARLA , Motoyoshi SEKIYA
发明人: Xi WANG , Qiong ZHANG , Paparao PALACHARLA , Motoyoshi SEKIYA
CPC分类号: H04Q11/00 , H04J14/00 , H04L41/142 , H04L41/145 , H04Q2213/13164 , H04Q2213/13335
摘要: An optical network analysis tool includes a computer-readable storage medium having computer-readable instructions stored thereon. The computer-readable instructions are executable by a computing device to perform operations. The operations include generating a simulated network that models an optical network. The simulated network includes regenerator candidate sites. The operations may also include conducting an analysis of the optical network. The analysis includes introducing a multiple signals transmitted between source/destination pairs and recording a number of times each of the regenerator candidate sites are selected as a regenerator site while applying each of a set of data traffic conditions in the simulated network. The operations may also include statistically analyzing the number of times each of the regenerator candidate sites is selected to generate statistically analyzed information and presenting the statistically analyzed information.
摘要翻译: 光网络分析工具包括其上存储有计算机可读指令的计算机可读存储介质。 计算机可读指令可由计算设备执行以执行操作。 这些操作包括生成模拟光网络的模拟网络。 模拟网络包括再生器候选站点。 这些操作还可以包括进行光网络的分析。 分析包括引入在源/目的地对之间传输的多个信号,并且在将模拟网络中的一组数据业务条件应用中的每一个的同时,将每个再生器候选站点选择为多个次数作为再生站站点进行记录。 操作还可以包括统计分析每个再生器候选位点被选择以产生统计分析的信息并呈现统计分析的信息的次数。
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公开(公告)号:US20160176882A1
公开(公告)日:2016-06-23
申请号:US14977273
申请日:2015-12-21
申请人: Ho Man CHAN , Xiang-Ju Justin GU , Ying HUANG , Ling LI , Yuan MI , Wei QI , Martin SENDZIK , Yongfeng SUN , Long WANG , Zhengtian YU , Hailong ZHANG , Ji Yue (Jeff) ZHANG , Man ZHANG , Qiong ZHANG , Kehao ZHAO
发明人: Ho Man CHAN , Xiang-Ju Justin GU , Ying HUANG , Ling LI , Yuan MI , Wei QI , Martin SENDZIK , Yongfeng SUN , Long WANG , Zhengtian YU , Hailong ZHANG , Ji Yue (Jeff) ZHANG , Man ZHANG , Qiong ZHANG , Kehao ZHAO
IPC分类号: C07D487/04 , A61K31/551 , A61K31/5377 , A61K31/541 , A61K31/519 , A61K45/06
CPC分类号: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06 , C07D487/04
摘要: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.
摘要翻译: 提供式(I)化合物或其药学上可接受的盐,其已被证明可用于治疗PRC2介导的疾病或病症:其中R1,R2,R3,R4,R5和n如所定义 这里。
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7.
公开(公告)号:US20100205075A1
公开(公告)日:2010-08-12
申请号:US12369160
申请日:2009-02-11
申请人: Qiong ZHANG
发明人: Qiong ZHANG
摘要: Pair-wise item affinity is based on transaction records. Each transaction record includes an indication of a bucket and an indication of an item transacted corresponding to that bucket. The method comprises a Phase 1 bucket filtering, Phase 2 item count, Phase 3 bucket materialization and Phase 4 pair count and affinity lift/calculation. The phases are ideally suited to be carried out by a computing system in a map-reduce configuration.
摘要翻译: 成对项目关联性基于事务记录。 每个交易记录包括桶的指示和对应于该桶的事务的指示。 该方法包括阶段1桶过滤,阶段2项目计数,阶段3桶实现和阶段4对计数和亲和力提升/计算。 这些阶段非常适合由地图缩减配置中的计算系统执行。
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