专利检索 ap:"Xiaojing Michael WANG" 第 1 页

1.

发明授权
Aminoheteroaryl benzamides as kinase inhibitors 有权
标题翻译：氨基杂芳基苯甲酰胺作为激酶抑制剂

公开(公告)号：US09242996B2

公开(公告)日：2016-01-26

申请号：US14527328

申请日：2014-10-29

申请人： Jeffrey T. Bagdanoff , Yu Ding , Wooseok Han , Zilin Huang , Qun Jiang , Jeff Xianming Jin , Xiang Kou , Patrick Lee , Mika Lindvall , Zhongcheng Min , Yue Pan , Sabina Pecchi , Keith Bruce Pfister , Daniel Poon , Vivek Rauniyar , Xiaojing Michael Wang , Qiong Zhang , Jianguang Zhou , Shejin Zhu

发明人： Jeffrey T. Bagdanoff , Yu Ding , Wooseok Han , Zilin Huang , Qun Jiang , Jeff Xianming Jin , Xiang Kou , Patrick Lee , Mika Lindvall , Zhongcheng Min , Yue Pan , Sabina Pecchi , Keith Bruce Pfister , Daniel Poon , Vivek Rauniyar , Xiaojing Michael Wang , Qiong Zhang , Jianguang Zhou , Shejin Zhu

IPC分类号： C07D213/73 , C07D401/06 , C07D403/06 , C07D498/04 , A61K31/4436 , A61K31/4545 , A61K31/4439 , A61K31/4965 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , C07D241/20 , C07D401/04 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D401/12

CPC分类号： A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04

摘要： The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

摘要翻译： 本发明提供式（I）的化合物或其盐; 和这些化合物的治疗用途。本发明还提供包含这些化合物的药物组合物，以及包含这些化合物与治疗性助剂的组合物。

2.

发明授权
Substituted 2,5-heterocyclic derivatives 失效
标题翻译：取代的2,5-杂环衍生物

公开(公告)号：US07470701B2

公开(公告)日：2008-12-30

申请号：US11095993

申请日：2005-03-30

申请人： Xiaodong Lin , Alice Rico , Xiaojing Michael Wang , Yasheen Zhou , Ann B. Jefferson , Annette Walter

发明人： Xiaodong Lin , Alice Rico , Xiaojing Michael Wang , Yasheen Zhou , Ann B. Jefferson , Annette Walter

IPC分类号： A61K31/506 , C07D401/04 , C07D239/42

CPC分类号： C07D409/04 , C07D409/14 , C07D413/14 , C07D417/14 , C07D495/04

摘要： The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula:

摘要翻译： 本发明涉及新的取代的五元化合物及其药学上可接受的盐，酯或前药，新化合物的组合物以及药学上可接受的载体，以及新化合物的用途。本发明的化合物具有以下通式：

3.

发明申请
Imidazoquinoline Compounds 审中-公开
标题翻译：咪唑喹啉化合物

公开(公告)号：US20080213308A1

公开(公告)日：2008-09-04

申请号：US11662984

申请日：2005-09-14

申请人： Nicholas Valiante , Feng Xu , Xiaodong Lin , Daniel Chu , Xiaojing Michael Wang

发明人： Nicholas Valiante , Feng Xu , Xiaodong Lin , Daniel Chu , Xiaojing Michael Wang

IPC分类号： C07D471/04 , A61K31/437 , A61K39/02 , A61K39/12 , A61K39/145 , A61K39/245 , A61K39/29 , A61P31/12

CPC分类号： C07D471/14 , C07D471/04 , Y02P20/55

摘要： The invention provides novel compositions comprising imidazoquinoline compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s).

摘要翻译： 本发明提供包含咪唑并喹啉化合物的新型组合物。还提供了以有效量施用组合物以增强受试者的免疫应答的方法。进一步提供了组合物与（一种或多种）其它试剂组合施用的新组合物和方法。

4.

发明申请
IMIDAZOQUINOLINE COMPOUNDS 审中-公开
标题翻译：咪唑啉化合物

公开(公告)号：US20130096103A1

公开(公告)日：2013-04-18

申请号：US13527537

申请日：2012-06-19

申请人： Nicholas VALIANTE , Feng Xu , Xiaodong Lin , Daniel Chu , Xiaojing Michael Wang

发明人： Nicholas VALIANTE , Feng Xu , Xiaodong Lin , Daniel Chu , Xiaojing Michael Wang

IPC分类号： C07D471/14

CPC分类号： C07D471/14 , C07D471/04 , Y02P20/55

摘要： The invention provides novel compositions comprising imidazoquinoline compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s).

摘要翻译： 本发明提供包含咪唑并喹啉化合物的新型组合物。还提供了以有效量施用组合物以增强受试者的免疫应答的方法。进一步提供了组合物与（一种或多种）其它试剂组合施用的新组合物和方法。

5.

发明申请
QUINAZOLINES FOR PDK1 INHIBITION 审中-公开
标题翻译：用于PDK1抑制剂的喹唑啉

公开(公告)号：US20100216767A1

公开(公告)日：2010-08-26

申请号：US12448390

申请日：2007-12-20

申请人： Mina Aikawa , Payman Amiri , Steven Bashman , Jeffrey Dove , Rama Jain , Xiaodong Lin , Jeremy Murray , Savithri Ramurthy , Alice Rico , Wei Shu , Sharadha Subramanian , Xiaojing Michael Wang , Robert L. Warne , Yasheen Zhou

发明人： Mina Aikawa , Payman Amiri , Steven Bashman , Jeffrey Dove , Rama Jain , Xiaodong Lin , Jeremy Murray , Savithri Ramurthy , Alice Rico , Wei Shu , Sharadha Subramanian , Xiaojing Michael Wang , Robert L. Warne , Yasheen Zhou

IPC分类号： A61K31/337 , C07D239/84 , A61K31/517 , C07D401/12 , A61K31/496 , C07D403/10 , C07D413/10 , A61K31/5377 , C07D413/14 , C07D403/12 , A61P35/00

CPC分类号： C07D239/84 , C07D401/08 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D411/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/14

摘要： The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

摘要翻译： 本发明提供了作为PDK1抑制剂的新型化合物。还提供了包含该化合物的药物组合物，以及用化合物或组合物治疗增殖性疾病如癌症的方法。

6.

发明申请
Novel compounds for treating proliferative diseases 审中-公开
标题翻译：用于治疗增殖性疾病的新型化合物

公开(公告)号：US20100121052A1

公开(公告)日：2010-05-13

申请号：US12456032

申请日：2009-06-09

申请人： Rama Jain , Xiaodong Lin , Simon C. Ng , Keith B. Pfister , Savithri Ramurthy , Alice Rico , Sharadha Subramanian , Xiaojing Michael Wang

发明人： Rama Jain , Xiaodong Lin , Simon C. Ng , Keith B. Pfister , Savithri Ramurthy , Alice Rico , Sharadha Subramanian , Xiaojing Michael Wang

IPC分类号： C07D239/84 , C07D417/10 , C07D401/12 , C07D413/12 , C07D401/14 , C07D413/14

CPC分类号： C07D417/04 , C07D239/84 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14

摘要： The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

摘要翻译： 本发明提供了作为PDK1抑制剂的新型化合物。还提供了包含该化合物的药物组合物，以及用化合物或组合物治疗增殖性疾病如癌症的方法。

7.

发明申请
SUBSTITUTED 2,5-HETEROCYCLIC DERIVATIVES 审中-公开
标题翻译：取代的2,5-杂环衍生物

公开(公告)号：US20080255120A1

公开(公告)日：2008-10-16

申请号：US12129367

申请日：2008-05-29

申请人： Xiaodong Lin , Alice Rico , Xiaojing Michael Wang , Yasheen Zhou , Ann B. Jefferson , Annette Walter

发明人： Xiaodong Lin , Alice Rico , Xiaojing Michael Wang , Yasheen Zhou , Ann B. Jefferson , Annette Walter

IPC分类号： A61K31/5377 , C07D409/04 , A61K31/506 , C07D513/04 , A61P35/00 , A61K31/519 , C07D413/14

CPC分类号： C07D409/04 , C07D409/14 , C07D413/14 , C07D417/14 , C07D495/04

摘要： The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula:

摘要翻译： 本发明涉及新的取代的五元化合物及其药学上可接受的盐，酯或前药，新化合物的组合物以及药学上可接受的载体，以及新化合物的用途。本发明的化合物具有以下通式：