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公开(公告)号：US08293509B2
公开(公告)日：2012-10-23
申请号：US12529761
申请日：2008-03-19
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew James Rowe , Phuong Loan Tran , Christophe Collet
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew James Rowe , Phuong Loan Tran , Christophe Collet
摘要： The invention relates to biological processes for producing one or more desired products, including alcohols such as ethanol and butanol. The processes comprise carrying out first and second fermentations of substrates in first and second bioreactors, wherein each fermentation produces one or more desired products and/or one or more by-products that can be utilized in the other fermentation. A product and/or by-product of the first fermentation is introduced to the second bioreactor during the fermentation, and a product and/or by-product of the second fermentation is introduced to the first bioreactor during the fermentation.
摘要翻译： 本发明涉及生产一种或多种所需产物的生物方法，包括醇如乙醇和丁醇。 该方法包括在第一和第二生物反应器中进行底物的第一次和第二次发酵，其中每次发酵产生一种或多种所需产物和/或可用于其它发酵的一种或多种副产物。 在发酵期间将第一发酵的产物和/或副产物引入第二生物反应器，并且在发酵期间将第二发酵的产物和/或副产物引入第一生物反应器。
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公开(公告)号：US08119378B2
公开(公告)日：2012-02-21
申请号：US12921584
申请日：2009-02-18
申请人： Sean Dennis Simpson , Christophe Collet , Phuong Loan Tran , Bakir Al-Sinawi , Richard Llewellyn Sydney Forster , Matthew James Rowe , Gary Chan , Kelly Marie Mahar , Jennifer Mon Yee Fung
发明人： Sean Dennis Simpson , Christophe Collet , Phuong Loan Tran , Bakir Al-Sinawi , Richard Llewellyn Sydney Forster , Matthew James Rowe , Gary Chan , Kelly Marie Mahar , Jennifer Mon Yee Fung
IPC分类号： C12P7/06 , C12P7/00 , C12N1/20 , C12P1/00 , C12P1/04 , C12P7/16 , C12P7/52 , C12P7/54 , C12M1/36
摘要： The invention relates to the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of substrates comprising CO. It more particularly relates to processes for the production of alcohols from their corresponding acids in the presence of a substrate comprising CO. In particular embodiments, a fermentation reaction producing acid(s) and optionally alcohol(s) is perturbed such that at least a portion one or more of acid(s) is converted to alcohol.
摘要翻译： 本发明涉及通过微生物发酵生产醇，特别是通过微生物发酵包含CO的底物来生产醇。更具体地涉及在含有CO的底物存在下从其相应的酸生产醇的方法。 特定的实施方案中，产生酸和任选的醇的发酵反应被扰动，使得至少一部分一种或多种酸被转化成醇。
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公开(公告)号：US08376736B2
公开(公告)日：2013-02-19
申请号：US12739424
申请日：2008-10-23
申请人： Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
发明人： Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
CPC分类号： C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要： The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
摘要翻译： 本发明涉及通过包含CO的气态底物的微生物发酵来捕获碳的方法。本发明的方法包括将CO转化为一种或多种包括醇和/或酸的产物，并任选地捕获CO 2以改善总体碳捕获。 在某些方面，本发明涉及从工业废物流，特别是炼钢厂废气中生产醇，特别是乙醇的方法。
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公开(公告)号：US08119844B2
公开(公告)日：2012-02-21
申请号：US12428829
申请日：2009-04-23
CPC分类号： C07C29/74 , C12P7/16 , Y02E50/10 , C07C31/225
摘要： The invention relates to methods for the production of alcohols by microbial fermentation, particularly microbial fermentation of substrates comprising glycerol and/or acetate, to butanol.
摘要翻译： 本发明涉及通过微生物发酵生产醇的方法，特别是包含甘油和/或乙酸酯的底物至丁醇的微生物发酵方法。
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公开(公告)号：US08507228B2
公开(公告)日：2013-08-13
申请号：US12821468
申请日：2010-06-23
申请人： Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley , Michael Kopke
发明人： Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley , Michael Kopke
IPC分类号： A61L9/01 , C02F3/00 , C02F3/34 , C12P1/04 , C12P7/00 , C12P7/02 , C12P7/04 , C12P7/06 , C12P7/08 , C12P7/40 , C12P7/54 , C12P7/62
CPC分类号： C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要： The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
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公开(公告)号：US20110059499A1
公开(公告)日：2011-03-10
申请号：US12921584
申请日：2009-02-18
申请人： Sean Dennis Simpson , Christophe Collet , Phuong Loan Tran , Bakir Al-Sinawi , Richard Llewellyn Sydney Forster , Matthew James Rowe , Gary Chan , Kelly Marie Mahar , Jennifer Mon Yee Fung
发明人： Sean Dennis Simpson , Christophe Collet , Phuong Loan Tran , Bakir Al-Sinawi , Richard Llewellyn Sydney Forster , Matthew James Rowe , Gary Chan , Kelly Marie Mahar , Jennifer Mon Yee Fung
摘要： The invention relates to the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of substrates comprising CO. It more particularly relates to processes for the production of alcohols from their corresponding acids in the presence of a substrate comprising CO. In particular embodiments, a fermentation reaction producing acid(s) and optionally alcohol(s) is perturbed such that at least a portion one or more of acid(s) is converted to alcohol.
摘要翻译： 本发明涉及通过微生物发酵生产醇，特别是通过微生物发酵包含CO的底物来生产醇。更具体地涉及在含有CO的底物存在下从其相应的酸生产醇的方法。 特定的实施方案中，产生酸和任选的醇的发酵反应被扰动，使得至少一部分一种或多种酸被转化成醇。
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公开(公告)号：US20100105115A1
公开(公告)日：2010-04-29
申请号：US12529761
申请日：2008-03-19
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew James Rowe , Phuong Loan Tran , Christophe Collet
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew James Rowe , Phuong Loan Tran , Christophe Collet
摘要： The invention relates to biological processes for producing one or more desired products, including alcohols such as ethanol and butanol. The processes comprise carrying out first and second fermentations of substrates in first and second bioreactors, wherein each fermentation produces one or more desired products and/or one or more by-products that can be utilised in the other fermentation. A product and/or by-product of the first fermentation is introduced to the second bioreactor during the fermentation, and a product and/or by-product of the second fermentation is introduced to the first bioreactor during the fermentation.
摘要翻译： 本发明涉及生产一种或多种所需产物的生物方法，包括醇如乙醇和丁醇。 该方法包括在第一和第二生物反应器中进行底物的第一次和第二次发酵，其中每次发酵产生一种或多种所需产物和/或可用于其它发酵的一种或多种副产物。 在发酵期间将第一发酵的产物和/或副产物引入第二生物反应器，并且在发酵期间将第二发酵的产物和/或副产物引入第一生物反应器。
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公开(公告)号：US20120309075A1
公开(公告)日：2012-12-06
申请号：US13537798
申请日：2012-06-29
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
IPC分类号： C12N1/20
CPC分类号： C12R1/145 , C12N1/20 , C12P7/065 , C12P7/08 , C12P7/54 , Y02E50/17 , Y10S435/821 , Y10S435/842
摘要： A biologically pure isolate of a selected bacterium derived from Clostridium autoethanogenum is described which has improved efficiency in the production of ethanol by anaerobic fermentation of substrates comprising carbon monoxide. The bacterium can produce ethanol and acetate at an ethanol to acetate ratio of at least 1.0 and has a productivity of at least 1.2 g of ethanol/l of fermentation broth per day. The bacterium is also characterized in that it has substantially no ability to sporulate.
摘要翻译： 描述了一种来源于自发性梭菌（Clostridium autoethanogenum）的选定细菌的生物纯的分离物，其通过包含一氧化碳的底物的厌氧发酵而提高了乙醇生产的效率。 该细菌可以以至少1.0的乙醇与乙酸酯比率生产乙醇和乙酸盐，并且每天产生至少1.2g乙醇/ l的发酵液。 细菌的特征还在于其基本上不具有孢子形成能力。
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公开(公告)号：US07972824B2
公开(公告)日：2011-07-05
申请号：US12296300
申请日：2007-04-05
摘要： The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilize hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilizing hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译： 本发明涉及提高厌氧发酵方法（1）的效率的方法（1），除了所需产物外，还可以生产作为副产物的乙酸酯，和（2）可以在发酵中利用氢和/或二氧化碳。 该方法包括以下步骤：将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体，并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。 在具体方面，本发明涉及生产醇，特别是乙醇的方法。
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公开(公告)号：US20090203100A1
公开(公告)日：2009-08-13
申请号：US12296300
申请日：2007-04-05
摘要： The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilise hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilising hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译： 本发明涉及提高厌氧发酵方法（1）的效率的方法（1），除了所需产物外，还可以生产作为副产物的乙酸酯，和（2）可以在发酵中利用氢和/或二氧化碳。 该方法包括以下步骤：将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体，并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。 在具体方面，本发明涉及生产醇，特别是乙醇的方法。
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