Porous keratin construct and method of making the same
    2.
    发明申请
    Porous keratin construct and method of making the same 有权
    多孔角蛋白构建体及其制作方法

    公开(公告)号:US20090105456A1

    公开(公告)日:2009-04-23

    申请号:US12000222

    申请日:2007-12-11

    IPC分类号: C07K14/78

    摘要: The invention relates to a porous keratin construct material comprising keratin protein for use in wound healing applications. The porous keratin construct is capable of bio-absorbing into a wound to promote wound healing. The rate at which the construct bio-absorbs into the wound may be controlled altered by controlling the degree of disulfide cross-linking between the keratin proteins in the porous keratin construct. The invention is also related to a method of making the porous keratin construct.

    摘要翻译: 本发明涉及包含用于伤口愈合应用的角蛋白蛋白的多孔角蛋白构建体材料。 多孔角蛋白构建体能够生物吸收到伤口中以促进伤口愈合。 可以通过控制多孔角蛋白构建体中的角蛋白质之间的二硫键交联程度来改变构建物生物吸收到伤口中的速率。 本发明还涉及制造多孔角蛋白构建体的方法。

    Porous keratin construct and method of making the same
    3.
    发明授权
    Porous keratin construct and method of making the same 有权
    多孔角蛋白构建体及其制作方法

    公开(公告)号:US08124735B2

    公开(公告)日:2012-02-28

    申请号:US12000222

    申请日:2007-12-11

    IPC分类号: A61K38/17

    摘要: The invention relates to a porous keratin construct material comprising keratin protein for use in wound healing applications. The porous keratin construct is capable of bio-absorbing into a wound to promote wound healing. The rate at which the construct bio-absorbs into the wound may be controlled altered by controlling the degree of disulfide cross-linking between the keratin proteins in the porous keratin construct. The invention is also related to a method of making the porous keratin construct.

    摘要翻译: 本发明涉及包含用于伤口愈合应用的角蛋白蛋白的多孔角蛋白构建体材料。 多孔角蛋白构建体能够生物吸收到伤口中以促进伤口愈合。 可以通过控制多孔角蛋白构建体中的角蛋白质之间的二硫键交联程度来改变构建物生物吸收到伤口中的速率。 本发明还涉及制造多孔角蛋白构建体的方法。

    Nutritional Supplement
    8.
    发明申请
    Nutritional Supplement 审中-公开
    营养补品

    公开(公告)号:US20120219667A1

    公开(公告)日:2012-08-30

    申请号:US13381766

    申请日:2010-07-01

    摘要: Nutritional supplements comprising keratin protein either in powder or liquid form as well as novel methods of producing soluble keratin proteins by oxidation are provided. In one embodiment of the disclosure, a soluble keratin protein product can be produced by treating an insoluble keratin source in an oxidizing solution at low pH and heat for a sufficient time to oxidize essentially all of the cysteine residues in the protein. By then raising the pH to the pKa of the proteins, or to the point at which the protein is present in the salt form, a solution of high molecular weight proteins that are in a low salt solution can be obtained. This solution is essentially free of peptides and salts that have an adverse effect on flavor and palatability, and maintains a high proportion of sulfur amino acids for beneficial health effects. The resulting protein product can be dissolved into water, juice, or a nutritional drink, or sprinkled on food. Alternatively, the protein can be provided as a liquid supplement.

    摘要翻译: 提供包含粉末或液体形式的角蛋白的营养补充剂以及通过氧化产生可溶性角蛋白蛋白质的新方法。 在本公开的一个实施方案中,可以通过在低pH和热处理氧化溶液中的不溶性角蛋白源足够的时间来氧化蛋白质中的所有半胱氨酸残基来生产可溶性角蛋白产物。 然后,通过将pH提高到蛋白质的pKa,或将蛋白质以盐的形式存在,可以获得处于低盐溶液中的高分子量蛋白质的溶液。 该溶液基本上不含对味道和适口性有不利影响的肽和盐,并且保持高比例的硫氨基酸用于有益的健康效果。 所得到的蛋白质产物可溶于水,果汁或营养饮料中,或洒在食物上。 或者,蛋白质可以作为液体补充剂提供。