公开(公告)号：US20240103006A1

公开(公告)日：2024-03-28

申请号：US18468249

申请日：2023-09-15

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Maksim Fomin ,  Hannes Kuchelmeister

IPC: G01N33/68 ,  C07C259/06

CPC classification number: G01N33/6845 ,  C07C259/06 ,  G01N33/6842

Abstract: The present invention relates to chemical probes for the improved detection of cysteine in a test sample, preferably an aqueous test sample, as well as respective uses and kits.

公开(公告)号：US20230333095A1

公开(公告)日：2023-10-19

申请号：US18339799

申请日：2023-06-22

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Maksim Fomin ,  Dieter Heindl ,  Lars Hillringhaus ,  Hannes Kuchelmeister ,  Mohamed Yosry Hassan Mohamed ,  Tobias Oelschlaegel ,  Sona Simonyiova

IPC: G01N33/533 ,  G01N33/68 ,  C07F15/02

CPC classification number: G01N33/533 ,  G01N33/6887 ,  C07F15/025 ,  G01N2800/325

Abstract: The present invention relates to a method for determining at least one analyte of interest. The present invention further relates to a kit, a complex, a method to synthesize a complex and the use thereof for detecting the analyte of interest in the sample.

公开(公告)号：US20230324398A1

公开(公告)日：2023-10-12

申请号：US17990903

申请日：2022-11-21

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Dieter Heindl ,  Uwe Kobold ,  Hannes Kuchelmeister ,  Heribert Maerz ,  Giuseppe Prencipe ,  Martin Rempt

IPC: G01N33/58

CPC classification number: G01N33/58 ,  G01N2560/00

Abstract: The present invention relates to compounds which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said compounds.

公开(公告)号：US20230160904A1

公开(公告)日：2023-05-25

申请号：US17991366

申请日：2022-11-21

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Robert Hahn ,  Dieter Heindl ,  Hans-Peter Josel ,  Uwe Kobold ,  Hannes Kuchelmeister ,  Simon Loibl ,  Heribert Maerz ,  Giuseppe Prencipe ,  Martin Rempt

IPC: G01N33/68 ,  C07C243/34 ,  C07D401/04 ,  C07D213/55 ,  C07D213/74 ,  C07D213/56

CPC classification number: G01N33/6848 ,  C07C243/34 ,  C07D401/04 ,  C07D213/55 ,  C07D213/74 ,  C07D213/56 ,  G01N2560/00

Abstract: The present invention relates to compounds which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said compounds.

公开(公告)号：US20230127289A1

公开(公告)日：2023-04-27

申请号：US17990714

申请日：2022-11-20

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Robert Hahn ,  Dieter Heindl ,  Thomas Hoffmann ,  Hans-Peter Josel ,  Uwe Kobold ,  Hannes Kuchelmeister ,  Simon Ferdinand Loibl ,  Daniela Mazzier ,  Jelena Milic ,  Giuseppe Prencipe ,  Martin Rempt ,  Christoph Seidel

IPC: C07D213/56 ,  C07D401/04 ,  C07D213/74 ,  C07D213/30 ,  H01J49/00

Abstract: The present invention relates to compounds which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said compounds.