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公开(公告)号：US11099149B2
公开(公告)日：2021-08-24
申请号：US15604017
申请日：2017-05-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Michael Marquant , Christine Nortmeyer , Reiner Stein
IPC: G01N27/327 , C12Q1/00
Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
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公开(公告)号：US20210080420A1
公开(公告)日：2021-03-18
申请号：US17106620
申请日：2020-11-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Michael Marquant , Christine Nortmeyer , Reiner Stein
IPC: G01N27/327 , C12Q1/00
Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
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公开(公告)号：US20170226068A1
公开(公告)日：2017-08-10
申请号：US15290440
申请日：2016-10-11
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Christine Nortmeyer , Peter Gebauer , Stacy H. Duvall , Klaus Andreas Bauer-Espindola
IPC: C07D241/46 , C12Q1/26
CPC classification number: C07D241/46 , C12Q1/26
Abstract: The present invention relates to a chemical compound or a salt or solvate thereof being an 1-amino-phenazine derivative and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the aforesaid chemical compound. Moreover, the present invention relates to a method for determining the amount of an analyte in a sample, comprising contacting said sample with a chemistry matrix according to the present invention, estimating the amount of electrons liberated or consumed by the chemistry matrix in the presence of said liquid sample, and thereby determining the amount of an analyte in a liquid sample.
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Patent Agency Ranking
公开(公告)号：US10180420B2
公开(公告)日：2019-01-15
申请号：US14963576
申请日：2015-12-09
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Carina Horn , Michael Marquant , Christine Nortmeyer , Volker Unkrig
Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.
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公开(公告)号：US20170254772A1
公开(公告)日：2017-09-07
申请号：US15604017
申请日：2017-05-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Michael Marquant , Christine Nortmeyer , Reiner Stein
IPC: G01N27/327 , C12Q1/00
CPC classification number: G01N27/3272 , C12Q1/006 , G01N27/3274
Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
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公开(公告)号：US11774395B2
公开(公告)日：2023-10-03
申请号：US17106620
申请日：2020-11-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Michael Marquant , Christine Nortmeyer , Reiner Stein
IPC: G01N27/327 , C12Q1/00
CPC classification number: G01N27/3272 , C12Q1/006 , G01N27/3274
Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
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公开(公告)号：US09988358B2
公开(公告)日：2018-06-05
申请号：US15290440
申请日：2016-10-11
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Christine Nortmeyer , Peter Gebauer , Stacy H. Duvall , Klaus Andreas Bauer-Espindola
IPC: C07D241/46 , C12Q1/26
CPC classification number: C07D241/46 , C12Q1/26
Abstract: The present invention relates to a chemical compound or a salt or solvate thereof being an 1-amino-phenazine derivative and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the aforesaid chemical compound. Moreover, the present invention relates to a method for determining the amount of an analyte in a sample, comprising contacting said sample with a chemistry matrix according to the present invention, estimating the amount of electrons liberated or consumed by the chemistry matrix in the presence of said liquid sample, and thereby determining the amount of an analyte in a liquid sample.
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公开(公告)号：US20160091482A1
公开(公告)日：2016-03-31
申请号：US14963576
申请日：2015-12-09
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Klaus Andreas Bauer-Espindola , Carina Horn , Michael Marquant , Christine Nortmeyer , Volker Unkrig
CPC classification number: G01N33/492 , G01N21/6428 , G01N21/78 , G01N21/8483 , G01N27/02 , G01N27/12 , G01N27/3274 , G01N2021/7786
Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.
Abstract translation: 公开了一种用于检测体液中的至少一种分析物的方法，包括执行光学测量，其中至少一种测试化学品接触体液。 测试化学品是适于执行至少一个检测反应的光学测试化学品，其中由于检测反应而改变至少一种可光学检测的性质以提供至少一种光学测量值。 产生至少一个阻抗测量，其中经由阻抗测量电极将至少一个交流电信号施加到体液，并记录至少一个应答信号，并且产生至少一个阻抗测量值。 执行至少一个评估步骤，其中使用至少一个评估算法，并且使用光学测量值和阻抗测量值来确定体液中分析物的浓度。
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