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    3-substituted phenazine derivatives as antimicrobial agents
    1.
    发明授权
    3-substituted phenazine derivatives as antimicrobial agents 有权

    公开(公告)号：US12060334B2

    公开(公告)日：2024-08-13

    申请号：US17692536

    申请日：2022-03-11

    申请人： University of Florida Research Foundation, Incorporated

    发明人： Robert William Huigens, III ,  Hongfen Yang

    IPC分类号： C07D241/46 ,  A61K31/498

    CPC分类号： C07D241/46

    摘要： The present invention provides phenazine derivatives, such as compounds of Formula (I). The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides compositions, kits, uses, and methods that involve the compounds of the invention, which may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.

    Electrolyte Regeneration for Organic Redox Flow Batteries Based on Water-Soluble Phenzaine-Based Compounds
    2.
    发明公开
    Electrolyte Regeneration for Organic Redox Flow Batteries Based on Water-Soluble Phenzaine-Based Compounds 审中-公开

    公开(公告)号：US20230411662A1

    公开(公告)日：2023-12-21

    申请号：US18031751

    申请日：2020-11-30

    申请人： CMBLU Energy AG

    发明人： Olga Ekkert ,  Evgeny Larionov ,  Jan Hartwig ,  Eduard Baal

    IPC分类号： H01M8/18 ,  H01M8/04276 ,  C07D241/46 ,  C01C3/12

    CPC分类号： H01M8/188 ,  H01M8/04276 ,  C07D241/46 ,  C01C3/12

    摘要： The present invention provides a process for the regeneration of an electrolyte solution of a redox-flow battery containing at least one (preferably substituted) phenazine compound, said process comprising at least one of the following steps (a), (b) and (c): (a) treatment of the electrolyte solution to be regenerated in order to convert organic degradation compounds contained therein to a (substituted) phenazine compound; (b) removal of precipitated material from the electrolyte solution and subsequent modification of the precipitated organic degradation compounds to obtain a (substituted) phenazine compound; and (c) separation of redox active compounds other than (substituted) phenazine compounds in particular inorganic electrolytes, from an electrolyte solution containing (substituted) phenazine compounds, and/or separation of (substituted) phenazine compounds from a solution containing redox active compounds other than (substituted) phenazine compounds.