公开(公告)号：US20170183663A1

公开(公告)日：2017-06-29

申请号：US15395233

申请日：2016-12-30

Applicant: STC.UNM

Inventor： Anatoliy Markiv ,  Ravi Venkata Durvasula ,  Angray Singh Kang

IPC: C12N15/62 ,  C12N15/63

CPC classification number: C12N15/62 ,  A61K49/0045 ,  A61K49/0058 ,  A61N5/062 ,  C07K14/001 ,  C07K16/18 ,  C07K16/30 ,  C07K16/32 ,  C07K2317/62 ,  C07K2317/622 ,  C07K2319/00 ,  C07K2319/60 ,  C12N15/63 ,  C12Q1/04 ,  G01N33/53 ,  G01N33/582

Abstract: Embodiments of the present invention provide for the facile generation of a stable recombinant fusion polypeptides with intrinsic fluorescent properties. The recombinant antibodies may be suitable for qualitative and/or quantitative immunofluorescence analysis. Generally, the fluorescent polypeptides include a fluorescent domain comprising a C-terminus and an N-terminus; a first antibody domain covalently linked to the C-terminus; and a second antibody domain covalently linked to the N-terminus.