Methods for making and using a structural hydrogel polymer device

    公开(公告)号:US12193953B2

    公开(公告)日:2025-01-14

    申请号:US18524495

    申请日:2023-11-30

    Inventor: Scott M. Epstein

    Abstract: The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. One or more physical post-implantation dimensions of the device can be controlled by placing it in a solution that has a predetermined osmolarity and/or pH. In addition, the device can deliver an absorbed therapeutic agent to a target anatomical site. Alternatively, the device can function as a selective membrane to selectively absorb one or more target molecules from a body fluid.

    Structural hydrogel polymer device

    公开(公告)号:US10881537B2

    公开(公告)日:2021-01-05

    申请号:US14881753

    申请日:2015-10-13

    Inventor: Scott M. Epstein

    Abstract: The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. Catheters and stents are particular examples, and their composition, mechanical characteristics, and the significantly unique ability to conduct and allow fluids to pass from one end to the other without physiological rejection, inflammation, or manifestation of complications due to implant or otherwise undesirable outcomes when used for ambulatory and or therapeutic interventions is the purpose of the invention.

    CATHETER OR STENT DELIVERY SYSTEM
    4.
    发明申请
    CATHETER OR STENT DELIVERY SYSTEM 审中-公开
    导管或手提式输送系统

    公开(公告)号:US20140343684A1

    公开(公告)日:2014-11-20

    申请号:US14446893

    申请日:2014-07-30

    Inventor: Scott M. Epstein

    Abstract: A method for delivering catheters, and stents composed of soft, compliant polymers through anatomical passages. These devices have a bulbous anchorage end with a diameter greater than the rest of the catheter. To facilitate implant and delivery a pusher catheter or sheath with an internal lumen larger than the outer diameter of the catheter but smaller than the outer diameter of the bulbous anchorage end. The distal end of pusher catheter or the sheath physically engages the proximal end of the bulbous anchorage end and applies an axial force to coaxially advance the catheter over a guidewire though anatomical passages. This method allows a physician to move the catheter to an anatomical site without the device exhibiting buckling due to axial force applied. Similarly, this delivery method will allow more force to be applied to the distal end of the catheter diminishing the likelihood of buckling.

    Abstract translation: 一种通过解剖通道输送导管和由柔软柔顺聚合物构成的支架的方法。 这些装置具有直径大于导管的其余部分的球状锚固端。 为了便于植入和递送具有比导管的外径大的内腔的推进导管或护套,但小于球形锚固端的外径。 推进导管或护套的远端物理地接合球形锚固端的近端,并且通过解剖通道施加轴向力以将导管同轴地推进导丝。 该方法允许医师将导管移动到解剖部位,而不会由于施加轴向力而使装置出现屈曲。 类似地,这种递送方法将允许更多的力施加到导管的远端,减少屈曲的可能性。

    METHODS FOR MAKING AND USING A STRUCTURAL HYDROGEL POLYMER DEVICE

    公开(公告)号:US20210177630A1

    公开(公告)日:2021-06-17

    申请号:US17132493

    申请日:2020-12-23

    Inventor: Scott M. Epstein

    Abstract: The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. One or more physical post-implantation dimensions of the device can be controlled by placing it in a solution that has a predetermined osmolarity and/or pH. In addition, the device can deliver an absorbed therapeutic agent to a target anatomical site. Alternatively, the device can function as a selective membrane to selectively absorb one or more target molecules from a body fluid.

    Catheter or stent delivery system

    公开(公告)号:US10751206B2

    公开(公告)日:2020-08-25

    申请号:US16101670

    申请日:2018-08-13

    Inventor: Scott M. Epstein

    Abstract: A method for delivering catheters, and stents composed of soft, compliant polymers through anatomical passages. These devices have a bulbous or enlarged anchorage end with a diameter greater than the rest of the catheter. To facilitate implant and delivery a pusher catheter or sheath with an internal lumen larger than the outer diameter of the catheter but smaller than the outer diameter of the bulbous or enlarged anchorage end is provided. The distal end of pusher catheter or the sheath physically engages the proximal end of the bulbous or enlarged anchorage end and applies an axial force to coaxially advance the catheter over a guidewire through anatomical passages. This method allows a physician to move the catheter to an anatomical site without the device exhibiting buckling due to axial force applied. Similarly, this delivery method will allow more force to be applied to the distal end of the catheter diminishing the likelihood of buckling.

    Catheter or stent delivery system
    10.
    发明授权

    公开(公告)号:US10568753B2

    公开(公告)日:2020-02-25

    申请号:US14446893

    申请日:2014-07-30

    Inventor: Scott M. Epstein

    Abstract: A method for delivering catheters, and stents composed of soft, compliant polymers through anatomical passages. These devices have a bulbous anchorage end with a diameter greater than the rest of the catheter. To facilitate implant and delivery a pusher catheter or sheath with an internal lumen larger than the outer diameter of the catheter but smaller than the outer diameter of the bulbous anchorage end. The distal end of pusher catheter or the sheath physically engages the proximal end of the bulbous anchorage end and applies an axial force to coaxially advance the catheter over a guidewire though anatomical passages. This method allows a physician to move the catheter to an anatomical site without the device exhibiting buckling due to axial force applied. Similarly, this delivery method will allow more force to be applied to the distal end of the catheter diminishing the likelihood of buckling.

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