公开(公告)号：US11132797B2

公开(公告)日：2021-09-28

申请号：US16212027

申请日：2018-12-06

Applicant: Topcon Corporation

Inventor： Zaixing Mao ,  Zhenguo Wang ,  Kinpui Chan ,  Jonathan Liu ,  Jongsik Kim

IPC: G06T7/00 ,  G06T7/73 ,  G06T11/00 ,  A61B3/12 ,  G06K9/46 ,  G06K9/62 ,  A61B3/10

Abstract: A multimodal imaging system and method is capable of taking fundus images, automatically identifying regions of interest (ROIs) of the eye from the fundus images, and performing OCT imaging in the identified ROIs, where the OCT images can provide clinically relevant information for screening purposes. By automatically identifying the ROIs, expert intervention is not required to perform specialized OCT imaging and thus, such imaging and analysis can be provided at more facilities and for more subjects for a lower cost.

公开(公告)号：US11751762B2

公开(公告)日：2023-09-12

申请号：US16719305

申请日：2019-12-18

Applicant: Topcon Corporation

Inventor： Jongsik Kim ,  Ying Dong ,  Song Mei ,  Kinpui Chan ,  Zhenguo Wang ,  Zaixing Mao

IPC: A61B3/10 ,  A61B3/14 ,  A61B3/12 ,  G01N21/17

CPC classification number: A61B3/102 ,  A61B3/1225 ,  A61B3/14 ,  G01N21/17 ,  G01N2021/1787

Abstract: A low coherence imaging method comprises acquiring image data of an object with an interferometric imaging system, where the image data is from a location of the object at first and second times; determining a first depth profile from the image data from the location at the first time and a second depth profile from the image data of the location at the second time; determining a change with respect to depth between the first and second depth profiles; and determining a property, or identifying a location, of at least one dynamic particle in the object based on the change between the first and second depth profiles. The method is able to identify, analyze, and/or visualize dynamic particles with features comparable to at least fluorescein angiography, indocyanine green angiography, confocal scanning laser fluorescein angiography, confocal scanning laser indocyanine green angiography, and fluorescence microscopy images, without the use of a dye.

公开(公告)号：US20190206054A1

公开(公告)日：2019-07-04

申请号：US16212027

申请日：2018-12-06

Applicant: Topcon Corporation

Inventor： Zaixing Mao ,  Zhenguo Wang ,  Kinpui Chan ,  Jonathan Liu ,  Jongsik Kim

IPC: G06T7/00 ,  G06T7/73 ,  G06T11/00

CPC classification number: G06T7/0014 ,  A61B3/102 ,  A61B3/12 ,  G06K9/4628 ,  G06K9/627 ,  G06K2209/05 ,  G06T7/0012 ,  G06T7/73 ,  G06T11/008 ,  G06T2207/10101 ,  G06T2207/20081 ,  G06T2207/30041

Abstract: A multimodal imaging system and method is capable of taking fundus images, automatically identifying regions of interest (ROIs) of the eye from the fundus images, and performing OCT imaging in the identified ROIs, where the OCT images can provide clinically relevant information for screening purposes. By automatically identifying the ROIs, expert intervention is not required to perform specialized OCT imaging and thus, such imaging and analysis can be provided at more facilities and for more subjects for a lower cost.

公开(公告)号：US20210407088A1

公开(公告)日：2021-12-30

申请号：US17447465

申请日：2021-09-13

Applicant: Topcon Corporation

Inventor： Zaixing Mao ,  Zhenguo Wang ,  Kinpui Chan ,  Jonathan Liu ,  Jongsik Kim

IPC: G06T7/00 ,  G06T7/73 ,  G06T11/00 ,  A61B3/12 ,  G06K9/46 ,  G06K9/62 ,  A61B3/10

Abstract: A multimodal imaging system and method is capable of taking fundus images, automatically identifying regions of interest (ROIs) of the eye from the fundus images, and performing OCT imaging in the identified ROIs, where the OCT images can provide clinically relevant information for screening purposes. By automatically identifying the ROIs, expert intervention is not required to perform specialized OCT imaging and thus, such imaging and analysis can be provided at more facilities and for more subjects for a lower cost.

公开(公告)号：US11614321B2

公开(公告)日：2023-03-28

申请号：US16829673

申请日：2020-03-25

Applicant: TOPCON CORPORATION

Inventor： Jongsik Kim ,  Bin Cao ,  Song Mei ,  Kinpui Chan ,  Zhenguo Wang ,  Zaixing Mao

IPC: G01C1/04 ,  A61B3/10 ,  A61B3/113 ,  A61B3/14 ,  A61B3/12 ,  G01B11/06

Abstract: An interferometric method of identifying the thickness of an object that is too thin to be resolved by a Fourier transform of the interference signal includes applying a harmonic frequency modulation to an envelope of the interference signal. Where the object is a tear film, this method may be utilized to determine a thickness of the lipid layer of the tear film.

公开(公告)号：US20200309510A1

公开(公告)日：2020-10-01

申请号：US16829673

申请日：2020-03-25

Applicant: TOPCON CORPORATION

Inventor： Jongsik Kim ,  Bin Cao ,  Song Mei ,  Kinpui Chan ,  Zhenguo Wang ,  Zaixing Mao

IPC: G01B11/06 ,  A61B3/113 ,  A61B3/10 ,  A61B3/14

Abstract: An interferometric method of identifying the thickness of an object that is too thin to be resolved by a Fourier transform of the interference signal includes applying a harmonic frequency modulation to an envelope of the interference signal. Where the object is a tear film, this method may be utilized to determine a thickness of the lipid layer of the tear film.