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公开(公告)号:US20110166673A1
公开(公告)日:2011-07-07
申请号:US12965205
申请日:2010-12-10
IPC分类号: A61F2/02
CPC分类号: A61L27/3633 , A61F2/0063 , A61F2/0077 , A61F2/02 , A61L27/3625 , A61L27/3629 , A61L27/50 , A61L31/005
摘要: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
摘要翻译: 描述了具有包含可重塑胶原片材料的说明性移植物的多层或多层可植入手术移植物的实施方案,所述移植物包括一个或多个交织构件以将移植物缝合在一起以帮助防止层在处理期间分层或分离,并且初始 重塑阶段。 交织构件可以包括以期望的图案编织穿过生物材料层的缝合线,线,单个线迹,材料条等。 在一个实施方案中,交织构件包含药理学活性物质,例如药物,生长因子等,以在宿主组织中引发所需的生物反应。 在另一个实施方案中,移植物还包括在可重塑生物材料层内的增强材料,例如合成网,并由一个或多个交织构件缝合在一起。
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公开(公告)号:US09295757B2
公开(公告)日:2016-03-29
申请号:US12965205
申请日:2010-12-10
CPC分类号: A61L27/3633 , A61F2/0063 , A61F2/0077 , A61F2/02 , A61L27/3625 , A61L27/3629 , A61L27/50 , A61L31/005
摘要: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
摘要翻译: 描述了具有包含可重塑胶原片材料的说明性移植物的多层或多层可植入手术移植物的实施方案,所述移植物包括一个或多个交织构件以将移植物缝合在一起以帮助防止层在处理期间分层或分离,并且初始 重塑阶段。 交织构件可以包括以期望的图案编织穿过生物材料层的缝合线,线,单个线迹,材料条等。 在一个实施方案中,交织构件包含药理学活性物质,例如药物,生长因子等,以在宿主组织中引发所需的生物反应。 在另一个实施方案中,移植物还包括在可重塑生物材料层内的增强材料,例如合成网,并由一个或多个交织构件缝合在一起。
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公开(公告)号:US08501217B2
公开(公告)日:2013-08-06
申请号:US13018582
申请日:2011-02-01
IPC分类号: A61F2/02
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译: 提供了一种植入式移植物,其可以插入瘘道以封闭瘘的主要开口。 为了防止移植物的意外移位或将移植物从患者的瘘管挤出,移植物可以设置有从移植物的主体的至少一端侧向延伸的帽,其中帽可以与 移植物的主体,可附接到移植物的身体的至少一端,和/或沿着移植物的主体移动。 移植物还可以具有从移植物的身体的一端延伸的尾部,以帮助将移植物放置在瘘管道中。 移植物可以是由诸如异种移植材料的单一材料制成的整体单元,或者可以包括由相同或不同材料制成的不同部件。 还提供了关闭瘘管的方法。
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公开(公告)号:US20110077679A1
公开(公告)日:2011-03-31
申请号:US12959799
申请日:2010-12-03
IPC分类号: A61M29/00
CPC分类号: A61K35/38 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B90/39 , A61L31/005 , A61L31/18 , A61L2430/36
摘要: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
摘要翻译: 一种包括用于引起栓塞和治疗动脉瘤的胶原生物材料(10)的医疗装置(40)。 胶原生物材料(10)包括被配置成用于引起血管闭塞或包装动脉瘤腔的各种成分(16)的小肠粘膜下层(12)。
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公开(公告)号:US20100204782A1
公开(公告)日:2010-08-12
申请号:US12762796
申请日:2010-04-19
申请人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
发明人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
IPC分类号: A61F2/06
CPC分类号: A61L27/3683 , A61B90/39 , A61K35/38 , A61L27/24 , A61L27/3604 , A61L27/50 , A61L29/005 , A61L31/005
摘要: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
摘要翻译: 公开了一种医疗装置(5),更具体地,涉及可植入生物材料。 生物材料包括不透射线(22)胶原生物材料(10)。
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公开(公告)号:US07857825B2
公开(公告)日:2010-12-28
申请号:US10718155
申请日:2003-11-20
CPC分类号: A61K35/38 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B90/39 , A61L31/005 , A61L31/18 , A61L2430/36
摘要: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
摘要翻译: 一种包括用于引起栓塞和治疗动脉瘤的胶原生物材料(10)的医疗装置(40)。 胶原生物材料(10)包括被配置成用于引起血管闭塞或包装动脉瘤腔的各种成分(16)的小肠粘膜下层(12)。
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公开(公告)号:US07713552B2
公开(公告)日:2010-05-11
申请号:US10025282
申请日:2001-12-19
申请人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
发明人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
CPC分类号: A61L27/3683 , A61B90/39 , A61K35/38 , A61L27/24 , A61L27/3604 , A61L27/50 , A61L29/005 , A61L31/005
摘要: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
摘要翻译: 公开了一种医疗装置(5),更具体地,涉及可植入生物材料。 生物材料包括不透射线(22)胶原生物材料(10)。
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公开(公告)号:US09089626B2
公开(公告)日:2015-07-28
申请号:US12762796
申请日:2010-04-19
申请人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
发明人: Mark W. Bleyer , Michael C. Hiles , Umesh H. Patel
IPC分类号: A61K9/06 , A01N59/00 , A61F2/06 , A61L27/36 , A61K35/38 , A61L27/24 , A61L27/50 , A61L29/00 , A61L31/00 , A61B19/00
CPC分类号: A61L27/3683 , A61B90/39 , A61K35/38 , A61L27/24 , A61L27/3604 , A61L27/50 , A61L29/005 , A61L31/005
摘要: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
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公开(公告)号:US07897167B2
公开(公告)日:2011-03-01
申请号:US11472642
申请日:2006-06-21
IPC分类号: A61F2/02
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译: 提供了一种植入式移植物,其可以插入瘘道以封闭瘘的主要开口。 为了防止移植物的意外移位或将移植物从患者的瘘管挤出,移植物可以设置有从移植物的主体的至少一端侧向延伸的帽,其中帽可以与 移植物的主体,可附接到移植物的身体的至少一端,和/或沿着移植物的主体移动。 移植物还可以具有从移植物的身体的一端延伸的尾部,以帮助将移植物放置在瘘管道中。 移植物可以是由诸如异种移植材料的单一材料制成的整体单元,或者可以包括由相同或不同材料制成的不同部件。 还提供了关闭瘘管的方法。
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公开(公告)号:US08439942B2
公开(公告)日:2013-05-14
申请号:US12959799
申请日:2010-12-03
CPC分类号: A61K35/38 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B90/39 , A61L31/005 , A61L31/18 , A61L2430/36
摘要: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
摘要翻译: 一种包括用于引起栓塞和治疗动脉瘤的胶原生物材料(10)的医疗装置(40)。 胶原生物材料(10)包括被配置成用于引起血管闭塞或包装动脉瘤腔的各种成分(16)的小肠粘膜下层(12)。
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