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1.发明授权Substituted liposaccharides useful in the treatment and prevention of endotoxemia 失效用于治疗和预防内毒素血症的取代脂肪糖公开(公告)号：US07737129B2
公开(公告)日：2010-06-15
申请号：US11830412
申请日：2007-07-30
IPC分类号： A61K31/70
CPC分类号： C07H15/04 , A61K9/0073 , C07H3/04 , C07H11/00 , C07H15/12
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译： 提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。 还提供了制备这些试剂和在其中有用的中间体的方法。
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公开(公告)号：US5935938A
公开(公告)日：1999-08-10
申请号：US658656
申请日：1996-06-05
IPC分类号： C07H15/12 , A61K31/70 , A61K31/7028 , A61P31/00 , A61P31/04 , C07H3/04 , C07H11/00 , C07H11/04 , C07H13/06 , C07H15/04 , C13K5/00
CPC分类号： C07H15/04 , A61K9/0073 , C07H11/00 , C07H15/12 , C07H3/04
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
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3.发明授权Substituted liposaccharides useful in the treatment and prevention of endotoxemia 有权用于治疗和预防内毒素血症的取代脂肪糖公开(公告)号：US07994154B2
公开(公告)日：2011-08-09
申请号：US12781166
申请日：2010-05-17
IPC分类号： A61K31/70
CPC分类号： C07H15/04 , A61K9/0073 , C07H3/04 , C07H11/00 , C07H15/12
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译： 提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。 还提供了制备这些试剂和在其中有用的中间体的方法。
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公开(公告)号：US5843918A
公开(公告)日：1998-12-01
申请号：US472820
申请日：1995-06-07
申请人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
发明人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
IPC分类号： A61K31/35 , A61K31/351 , A61K31/739 , A61P31/04 , A61P31/12 , C07D309/10 , C07H3/04 , C07H5/04 , C07H5/06 , C07H7/02 , C07H11/04 , C07H13/06 , C07H15/10 , A61K31/715 , A61K31/72 , A61K31/73
CPC分类号： C07H13/06 , C07H3/04 , Y10S514/885
摘要： Disclosed are lipid A analogs useful for the treatment of septic shock and LPS-mediated activation of viral infection.
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公开(公告)号：US5750664A
公开(公告)日：1998-05-12
申请号：US461675
申请日：1995-06-05
IPC分类号： C07H15/12 , A61K31/70 , A61K31/7028 , A61P31/00 , A61P31/04 , C07H3/04 , C07H11/00 , C07H11/04 , C07H13/06 , C07H15/04 , C07H5/00
CPC分类号： C07H15/04 , A61K9/0073 , C07H11/00 , C07H15/12 , C07H3/04
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
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公开(公告)号：US5530113A
公开(公告)日：1996-06-25
申请号：US935050
申请日：1992-08-25
申请人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
发明人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
IPC分类号： C07H13/06 , C13K5/00 , A61K31/715 , C07K16/00
CPC分类号： C07H13/06
摘要： Disclosed are lipid A analogs useful for the treatment of septic shock and LPS-mediated activation of viral infection.
摘要翻译： 公开了可用于治疗败血性休克和LPS介导的病毒感染活化的脂质A类似物。
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7.发明申请SUBSTITUTED LIPOSACCHARIDES USEFUL IN THE TREATMENT AND PREVENTION OF ENDOTOXEMIA 有权用于治疗和预防内毒素的替代利妥昔单抗公开(公告)号：US20100227835A1
公开(公告)日：2010-09-09
申请号：US12781166
申请日：2010-05-17
IPC分类号： A61K31/7016 , A61P29/00
CPC分类号： C07H15/04 , A61K9/0073 , C07H3/04 , C07H11/00 , C07H15/12
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译： 提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。 还提供了制备这些试剂和在其中有用的中间体的方法。
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8.发明授权Substituted liposaccharides useful in the treatment and prevention of endotoxemia 失效用于治疗和预防内毒素血症的取代脂肪糖
公开(公告)号：US5681824A
公开(公告)日：1997-10-28
申请号：US461677
申请日：1995-06-05
IPC分类号： C07H15/12 , A61K31/70 , A61K31/7028 , A61P31/00 , A61P31/04 , C07H3/04 , C07H11/00 , C07H11/04 , C07H13/06 , C07H15/04
CPC分类号： C07H15/04 , A61K9/0073 , C07H11/00 , C07H15/12 , C07H3/04
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译： 提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。 还提供了制备这些试剂和在其中有用的中间体的方法。
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9.发明申请Substituted Liposaccharides Useful in the Treatment and Prevention of Endotoxemia 失效用于治疗和预防内毒素血症的取代脂肪糖公开(公告)号：US20080214802A1
公开(公告)日：2008-09-04
申请号：US11830412
申请日：2007-07-30
CPC分类号： C07H15/04 , A61K9/0073 , C07H3/04 , C07H11/00 , C07H15/12
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译： 提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。 还提供了制备这些试剂和在其中有用的中间体的方法。
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公开(公告)号：US5756718A
公开(公告)日：1998-05-26
申请号：US475492
申请日：1995-06-07
申请人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
发明人： William J. Christ , Lynn D. Hawkins , Tsutomu Kawata , Daniel P. Rossignol , Seiichi Kobayashi , Osamu Asano
IPC分类号： A61K31/35 , A61K31/351 , A61K31/739 , A61P31/04 , A61P31/12 , C07D309/10 , C07H3/04 , C07H5/04 , C07H5/06 , C07H7/02 , C07H11/04 , C07H13/06 , C07H15/10 , C08B3/04 , A61K31/70
CPC分类号： C07H13/06 , C07H3/04 , Y10S514/885
摘要： Disclosed are lipid A analogs useful for the treatment of septic shock and LPS-mediated activation of viral infection.
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