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Patent Agency Ranking
公开(公告)号：US20190381324A1
公开(公告)日：2019-12-19
申请号：US16009553
申请日：2018-06-15
Applicant: Wisconsin Alumni Research Foundation
Inventor： Xudong Wang , Weibo Cai , Guang Yao , Lei Kang
Abstract: The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge without the need for a battery. In this regard, the invention is self-powering and is automatically timed to stomach peristalsis. While sporadic stimulation to the vagal nerve would seem too infrequent to cause weight loss effects, electrical stimulation delivered at the optimal time (e.g., during food consumption) has been found to optimize the effects of vagal nerve stimulation, giving the user's brain a “full stomach” signal before the user over-consumes food.
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2.发明申请公开(公告)号：US20180271470A1
公开(公告)日：2018-09-27
申请号：US15928812
申请日：2018-03-22
Applicant: Wisconsin Alumni Research Foundation
Inventor： Weibo Cai , Robert Nickles , Reinier Hernandez , Stephen Graves
CPC classification number: A61B6/5217 , A61B5/425 , A61B6/037 , A61B6/4057 , A61K31/18 , A61K31/4422 , A61K51/00 , A61K51/121 , G01R33/481 , G06T7/0014 , G06T2207/10104 , G06T2207/30092
Abstract: Methods for imaging beta cells in pancreatic tissue using radioisotopes of manganese, which may be referred to as radiomanganese, are described. Example radioisotopes of manganese include Mn-52g, Mn-52m, and Mn-51. As one example, radiomanganese can be used to image pancreatic beta cells, in which radiomanganese shows a preferential uptake. This provides for applications such as quantifying beta cell mass (e.g., functional beta cell mass), assessing transplant viability, and monitoring the efficacy of drug treatments. A pharmacological agent can be administered to modulate the uptake of divalent metals by the pancreatic beta cells, which can be correlated to a modulated uptake of radiomanganese to estimate pancreatic beta cell mass, function, or both.
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公开(公告)号：US11344719B2
公开(公告)日：2022-05-31
申请号：US16376178
申请日：2019-04-05
Applicant: Wisconsin Alumni Research Foundation
Inventor： Xudong Wang , Yin Long , Weibo Cai , Hao Wei
Abstract: A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The electrical energy induces an electric potential across the wound opening producing accelerated skin wound recovery under the voltage fluctuations produced by the power generator.
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公开(公告)号：US11027140B2
公开(公告)日：2021-06-08
申请号：US16009553
申请日：2018-06-15
Applicant: Wisconsin Alumni Research Foundation
Inventor： Xudong Wang , Weibo Cai , Guang Yao , Lei Kang
Abstract: The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge without the need for a battery. In this regard, the invention is self-powering and is automatically timed to stomach peristalsis. While sporadic stimulation to the vagal nerve would seem too infrequent to cause weight loss effects, electrical stimulation delivered at the optimal time (e.g., during food consumption) has been found to optimize the effects of vagal nerve stimulation, giving the user's brain a “full stomach” signal before the user over-consumes food.
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公开(公告)号：US20200316366A1
公开(公告)日：2020-10-08
申请号：US16376178
申请日：2019-04-05
Applicant: Wisconsin Alumni Research Foundation
Inventor： Xudong Wang , Yin Long , Weibo Cai , Hao Wei
Abstract: A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The electrical energy induces an electric potential across the wound opening producing accelerated skin wound recovery under the voltage fluctuations produced by the power generator.
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