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公开(公告)号:US20120014941A1
公开(公告)日:2012-01-19
申请号:US12975784
申请日:2010-12-22
申请人: Xiumin Wu , Yan Wu , Lanlan Yu , Napoleone Ferrara , Wei-Ching Liang , Yu-Ju G. Meng , Janet Tien
发明人: Xiumin Wu , Yan Wu , Lanlan Yu , Napoleone Ferrara , Wei-Ching Liang , Yu-Ju G. Meng , Janet Tien
CPC分类号: C07K16/22 , A61K2039/505 , A61K2039/507 , C07K16/24 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The present invention concerns antibodies to Bv8 and the uses of same.
摘要翻译: 本发明涉及Bv8的抗体及其用途。
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公开(公告)号:US08771685B2
公开(公告)日:2014-07-08
申请号:US12975784
申请日:2010-12-22
申请人: Xiumin Wu , Yan Wu , Lanlan Yu , Napoleone Ferrara , Wei-Ching Liang , Yu-Ju G. Meng , Janet Tien
发明人: Xiumin Wu , Yan Wu , Lanlan Yu , Napoleone Ferrara , Wei-Ching Liang , Yu-Ju G. Meng , Janet Tien
IPC分类号: A61K39/395
CPC分类号: C07K16/22 , A61K2039/505 , A61K2039/507 , C07K16/24 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The present invention concerns antibodies to Bv8 and the uses of same.
摘要翻译: 本发明涉及Bv8的抗体及其用途。
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公开(公告)号:US09109035B2
公开(公告)日:2015-08-18
申请号:US13450326
申请日:2012-04-18
申请人: Wei-Ching Liang , Chie Sakanaka , Yan Wu
发明人: Wei-Ching Liang , Chie Sakanaka , Yan Wu
CPC分类号: A61K47/48638 , A61K47/6811 , A61K47/6851 , A61K47/6889 , A61K51/1045 , A61K2039/505 , C07K16/005 , C07K16/30 , C07K16/3069 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , C12N9/96
摘要: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗TAT226抗体及其免疫偶联物。 提供了使用抗TAT226抗体及其免疫偶联物的方法。
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公开(公告)号:US20120329094A1
公开(公告)日:2012-12-27
申请号:US13559464
申请日:2012-07-26
申请人: Allen J. Ebens, JR. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, JR. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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5.
公开(公告)号:US20100172921A1
公开(公告)日:2010-07-08
申请号:US12598537
申请日:2007-05-17
IPC分类号: A61K39/395 , A61P35/02 , A61P35/00 , A61P35/04 , C07K16/30
CPC分类号: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/31 , C07K2317/622 , C07K2317/76 , C07K2317/92
摘要: The application provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
摘要翻译: 该应用提供Nrp2拮抗剂,例如抗Nrp2抗体,以及它们在预防和治疗肿瘤转移中的用途。
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公开(公告)号:US08524865B2
公开(公告)日:2013-09-03
申请号:US11754899
申请日:2007-05-29
申请人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US20120148572A1
公开(公告)日:2012-06-14
申请号:US13112833
申请日:2011-05-20
申请人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
发明人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
IPC分类号: A61K39/395 , C12N9/96 , C12N15/13 , C12N15/63 , C12N5/16 , A61P9/00 , A61P35/00 , A61P27/02 , G01N33/566 , C07K16/28 , C12P21/02
CPC分类号: C07K16/2842 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.
摘要翻译: 本发明涉及VEGF拮抗剂和新型抗α5抗体用于治疗癌症并抑制血管生成和/或血管通透性的用途,包括抑制疾病中的异常血管生成。 本发明还涉及包含新的抗α5和bgr1抗体的组合物和试剂盒,以及制备和使用它们的方法。
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公开(公告)号:US20120100159A1
公开(公告)日:2012-04-26
申请号:US11687309
申请日:2007-03-16
申请人: Wei-Ching Liang , Chie Sakanaka , Yan Wu
发明人: Wei-Ching Liang , Chie Sakanaka , Yan Wu
IPC分类号: A61K39/395 , C12N15/13 , C12N15/63 , C12N5/10 , A61P35/00 , G01N33/574 , C12N9/96 , C07K19/00 , C12N5/09 , C07K16/30 , C12P21/02
CPC分类号: A61K47/48638 , A61K47/6811 , A61K47/6851 , A61K47/6889 , A61K51/1045 , A61K2039/505 , C07K16/005 , C07K16/30 , C07K16/3069 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , C12N9/96
摘要: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗TAT226抗体及其免疫偶联物。 提供了使用抗TAT226抗体及其免疫偶联物的方法。
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公开(公告)号:US09284376B2
公开(公告)日:2016-03-15
申请号:US13112833
申请日:2011-05-20
申请人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
发明人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
CPC分类号: C07K16/2842 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.
摘要翻译: 本发明涉及VEGF拮抗剂和新型抗α5抗体用于治疗癌症并抑制血管生成和/或血管通透性的用途,包括抑制疾病中的异常血管生成。 本发明还涉及包含新型抗α5和bgr1抗体的组合物和试剂盒,以及制备和使用它们的方法。
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公开(公告)号:US08962275B2
公开(公告)日:2015-02-24
申请号:US13335632
申请日:2011-12-22
申请人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
发明人: Wei-Ching Liang , Gregory D. Plowman , Yan Wu , Weilan Ye
IPC分类号: C07H21/04 , C12P21/06 , C12N15/87 , C12N1/20 , C12N15/74 , C07K16/28 , C07K16/22 , A61K39/00
CPC分类号: C07K16/2842 , A61K47/6835 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K2317/24 , C07K2317/31 , C07K2317/56 , C07K2317/565 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412
摘要: The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
摘要翻译: 本发明提供新的抗α5和bgr1抗体,包含抗体的组合物和试剂盒,以及制备和使用抗体的方法。
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