公开(公告)号：US06440890B1

公开(公告)日：2002-08-27

申请号：US09656126

申请日：2000-09-06

Applicant: Rupert Edward von Haken Spence ,  Stephen John Brown ,  Ryan Paul Wurz ,  Dusan Jeremic ,  Douglas W. Stephan

Inventor： Rupert Edward von Haken Spence ,  Stephen John Brown ,  Ryan Paul Wurz ,  Dusan Jeremic ,  Douglas W. Stephan

IPC: B01J3124

CPC classification number: B01J31/188 ,  B01J31/2295 ,  B01J31/38 ,  B01J2531/46 ,  C07F17/00 ,  C08F4/65908 ,  C08F4/65912 ,  C08F10/00 ,  C08F210/16 ,  Y10S526/943 ,  C08F4/65925 ,  C08F210/08 ,  C08F2500/03 ,  C08F210/14

Abstract: New group 4 organometallic complexes are characterized by having a phosphinimine ligand and two or more cyclopentadienyl ligands. Certain of these complexes exhibit unusual behavior when examined by nuclear magnetic resonance (NMR) techniques. Well defined crystals of the inventive complexes have been isolated and analyzed by x-ray crystallography. The complexes have also been found to be polymerization catalysts which are surprisingly more active than their simple metallocene analogs.

Abstract translation: 新的4族有机金属络合物的特征在于具有膦亚胺配体和两个或更多个环戊二烯基配体。 当通过核磁共振（NMR）技术检查时，这些复合物中的某些复合物表现出异常的行为。 已经通过x射线晶体学分离和分析本发明复合物的定义良好的晶体。 复合物也被发现是聚合催化剂，它们比其简单的茂金属类似物更令人惊奇地更具活性。

公开(公告)号：US06586357B1

公开(公告)日：2003-07-01

申请号：US09938354

申请日：2001-08-24

Applicant: Patrizia Antognazza ,  Tiziana Benincori ,  Elisabetta Brenna ,  Edoardo Cesarotti ,  Francesco Sannicolo′ ,  Licia Trimarco

Inventor： Patrizia Antognazza ,  Tiziana Benincori ,  Elisabetta Brenna ,  Edoardo Cesarotti ,  Francesco Sannicolo′ ,  Licia Trimarco

IPC: B01J3124

CPC classification number: C07F15/008 ,  B01J31/1865 ,  B01J31/2295 ,  B01J31/2409 ,  B01J31/2452 ,  B01J2231/645 ,  B01J2531/0266 ,  B01J2531/52 ,  B01J2531/82 ,  B01J2531/821 ,  B01J2531/822 ,  C07C67/303 ,  C07C67/31 ,  C07F9/5728 ,  C07F9/65515 ,  C07F9/65517 ,  C07F9/655345 ,  C07F9/655354 ,  C07F15/0053 ,  C07F15/0073 ,  C07C69/675 ,  C07C69/732

Abstract: Chiral diphosphines constituted by an aromatic pentatomic biheterocyclic system, suitable to act as chiral ligands, complexes between said diphosophines and transition metals, and their utilization as chiral catalysts in sterocontrolled reactions, such as diastereo- and enantioselective reduction reactions. Process for the preparation of said chiral diphosophines and process for the preparation of said complexes and for their utilization as chiral catalysts in sterocontrolled reactions.

Abstract translation: 由芳族五原子双杂环系统构成的手性二膦系，其适合作为手性配体，所述二磷酸和过渡金属之间的复合物，以及它们作为异步反应中的手性催化剂的用途，例如非对映选择性还原反应。 用于制备所述手性二硫辛酸的方法和制备所述复合物的方法及其作为在sterocontrolled反应中的手性催化剂的使用。

公开(公告)号：US06417363B1

公开(公告)日：2002-07-09

申请号：US09555308

申请日：2000-05-26

Applicant: Paul Adriaan Van Der Schaaf ,  Andreas Mühlebach ,  Andreas Hafner ,  Roman Kolly

Inventor： Paul Adriaan Van Der Schaaf ,  Andreas Mühlebach ,  Andreas Hafner ,  Roman Kolly

IPC: B01J3124

CPC classification number: C08G61/06 ,  C07F15/002 ,  C07F15/0046

Abstract: Penta- and hexa-coordinated, bridged ruthenium and osmium catalysts of the formula wherein Me is ruthenium or osmium; L1 and L2 are neutral ligands having electron donor properties; X is an anionic ligand; Y is oxygen or sulphur; A is a direct bond, C1-C4alkylene or C2-C4alkylidene; Z is a direct bond, oxygen, sulphur or the groups wherein R1 and R2 are hydrogen or hydrocarbon radicals; their preparation and their us in the synthesis of polymers, in the ring-closure metathesis of diolefins, in the cross metathesis of olefins and in the isomerisation of olefins are disclosed.

Abstract translation: 锑化合物Me的五和六配位的桥联钌和锇催化剂是钌或锇; L1和L2是具有电子给体性质的中性配体; X是阴离子配体; Y是氧或硫; A是直接键，C1-C4亚烷基或C2-C4亚烷基; Z是直接键，氧，硫或其中R1和R2是氢或烃基的基团; 公开了它们在聚合物的合成，二烯烃的闭环复分解，烯烃的交叉复分解和烯烃异构化中的制备及其制备。

公开(公告)号：US06730629B2

公开(公告)日：2004-05-04

申请号：US10315255

申请日：2002-12-10

Applicant: Kazuhiko Matsumura ,  Takao Saito

Inventor： Kazuhiko Matsumura ,  Takao Saito

IPC: B01J3124

CPC classification number: C07F15/04 ,  B01J31/2295 ,  B01J31/2433 ,  B01J31/2476 ,  B01J2231/645 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/847 ,  C07B53/00 ,  C07B2200/07 ,  C07C231/18 ,  C07F9/5027 ,  C07F9/65683 ,  C07C233/58

Abstract: A phosphine compound having excellent properties (chemical selectivity, enantioselectivity, catalytic activity) as a catalyst for asymmetric syntheses, especially asymmetric hydrogenations. A phosphine-phospholane compound represented by the following formula (1): a phosphine-primary phosphine intermediate; a transition metal complex including the phosphine-phospholane compound of formula (1) and a transition metal, and a catalyst including the transition metal complex.

Abstract translation: 具有优异特性（化学选择性，对映体选择性，催化活性）的膦化合物作为不对称合成的催化剂，特别是不对称氢化。 由下式（1）表示的膦 - 磷脂化合物：膦 - 伯膦中间体; 包括式（1）的膦 - 磷脂化合物和过渡金属的过渡金属络合物和包含过渡金属络合物的催化剂。

公开(公告)号：US06750171B2

公开(公告)日：2004-06-15

申请号：US10418684

申请日：2003-04-18

Applicant: Garrett Stewart Hoge, II ,  Om Prakash Goel

Inventor： Garrett Stewart Hoge, II ,  Om Prakash Goel

IPC: B01J3124

CPC classification number: C07F15/0073 ,  B01J31/1875 ,  B01J31/2404 ,  B01J31/2414 ,  B01J2231/643 ,  B01J2231/645 ,  B01J2531/822 ,  C07B53/00 ,  C07B2200/07 ,  C07F9/6568 ,  C07F9/65683 ,  C07F9/65685 ,  C07F15/00

Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

Abstract translation: 描述了P型手性双硫醇配体及其制备方法。 还描述了使用金属/ P-手性双磷脂络合物来催化不对称转化反应以提供形成的化合物的高对映体过量。

公开(公告)号：US06720281B2

公开(公告)日：2004-04-13

申请号：US10062027

申请日：2002-02-01

Applicant: Walter Leitner ,  Giancarlo Francio ,  Felice Faraone ,  Carmela G. Arena

Inventor： Walter Leitner ,  Giancarlo Francio ,  Felice Faraone ,  Carmela G. Arena

IPC: B01J3124

CPC classification number: C07F9/65683 ,  B01J31/2495 ,  B01J2231/321 ,  B01J2231/323 ,  B01J2231/645 ,  B01J2531/822 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/04 ,  C07C45/505 ,  C07C67/303 ,  C07F9/60 ,  C07C69/34 ,  C07C33/20 ,  C07C33/22

Abstract: The present invention relates to novel chiral phosphorus compounds which can be readily prepared from quinoline derivatives as inexpensive starting compounds and have the general formula I wherein R1, R2, R3, R4, R5 are chiral or achiral organic residues which are derived from substituted or unsubstituted straight or branched chain or cyclic aliphatic or aromatic groups and which, in the case of the pairs R1/R2 and R4/R5, may be interconnected. Further, the invention relates to the use of chiral phosphorus compounds of general formula I as catalysts or catalyst components in processes for the preparation of optically active products.

Abstract translation: 本发明涉及新颖的手性磷化合物，其可以容易地由喹啉衍生物制备为廉价的起始化合物，并具有通式I，其中R 1，R 2，R 3，R 4，R 5 是衍生自取代或未取代的直链或支链或环状脂族或芳族基团的手性或非手性有机残基，并且在对R 1 / R 2和R 4 / R' 5>，可以互连。 此外，本发明涉及在制备光学活性产物的方法中使用通式I的手性磷化合物作为催化剂或催化剂组分。

公开(公告)号：US06566298B2

公开(公告)日：2003-05-20

申请号：US10219750

申请日：2002-08-15

Applicant: Birgit Driessen-Hölscher ,  Joachim Kralik ,  Inga Ritzkopf ,  Christian Steffens ,  Guido Giffels ,  Claus Dreisbach ,  Thomas Prinz ,  Walter Lange

Inventor： Birgit Driessen-Hölscher ,  Joachim Kralik ,  Inga Ritzkopf ,  Christian Steffens ,  Guido Giffels ,  Claus Dreisbach ,  Thomas Prinz ,  Walter Lange

IPC: B01J3124

CPC classification number: B01J31/2409 ,  B01J2231/641 ,  B01J2231/645 ,  B01J2531/0266 ,  B01J2531/80 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/827 ,  C07C303/28 ,  C07D321/10 ,  C07F9/5027 ,  C07F9/5072 ,  C07F9/572 ,  C07F9/65515 ,  C07F15/0013 ,  C07F15/004 ,  C07F15/0053 ,  C07F15/008 ,  C07C309/65

Abstract: The invention relates to the preparation and use as catalysts of diphosphines of the formula (I) in which R is C6-C14-aryl or C4-C13-heteroaryl containing 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur, wherein the aryl and heteroaryl radicals may optionally be substituted by halogen, C1-C6-alkyl, C1-C6-alkoxy, and/or trimethylsilyl, and R1 to R4, independently of one another, are each hydrogen, C1-C10-alkyl, C1-C10-alkoxy, F, Cl, or Br.