Method and apparatus for using vagus nerve stimulation in surgery
    91.
    发明授权
    Method and apparatus for using vagus nerve stimulation in surgery 失效
    手术中使用迷走神经刺激的方法和装置

    公开(公告)号:US06308104B1

    公开(公告)日:2001-10-23

    申请号:US09338303

    申请日:1999-06-22

    IPC分类号: A61N105

    摘要: A method and apparatus for facilitating coronary surgery on the beating heart wherein the vagus nerve is electrically stimulated to purposely temporarily stop or substantially reduce the beating of the heart under precisely controlled conditions. The apparatus controllably applies the electrical stimulus to preselected locations along the vagus nerve and thus to preselected nerve branches related to the heart. The apparatus includes several clip and probe configurations for establishing electrical contact with the vagus nerve. Such purposely caused temporary stoppage or substantial reduction of the beating of the heart facilitates procedures such as suturing of an anastomosis which would otherwise be more difficult because of the motion induced by the beating heart.

    摘要翻译: 一种用于促进搏动心脏的冠状动脉手术的方法和装置,其中电刺激迷走神经以故意暂时地停止或基本上减少在精确控制的条件下的心跳。 该装置可控制地将电刺激应用于沿着迷走神经的预选位置,并因此应用于与心脏相关的预选神经分支。 该装置包括用于建立与迷走神经的电接触的多个夹子和探针配置。 这样有意地引起临时停止或大幅度减少心脏搏动的方法有助于诸如缝合吻合术的过程,否则由于跳动心脏引起的运动将更加困难。

    Expandable cannula for performing cardiopulmonary bypass and method for using same
    93.
    发明授权
    Expandable cannula for performing cardiopulmonary bypass and method for using same 失效
    用于进行体外循环的可扩展插管及其使用方法

    公开(公告)号:US06190357B1

    公开(公告)日:2001-02-20

    申请号:US09063588

    申请日:1998-04-21

    IPC分类号: A61M2900

    摘要: A device for occlusion of a body passageway and subsequent perfusion of the body passageway with arterial return blood, cardioplegia and other fluid is disclosed. The device of the present invention is an expandable cannula comprising a flexible, expandable tubular elongate body having a first diameter and a second diameter, wherein the expandable cannula is inserted having a first diameter and then expanded to a second diameter to provide perfusion flow to the body passageway through at least one arterial return aperture provided on the distal end of the expandable tubular elongate body in fluid communication with a perfusion lumen provided within the cannula. The device may be further provided with one or more additional lumens for providing additional functions to the vessel lumen and may also include an expandable occluding member fixed at the distal end of the cannula for isolating the surgical area from the rest of the arterial system. A preferred method of use of the present invention is also disclosed wherein having a first diameter is inserted endovascularly into the vessel of a patient and advanced to a point of interest. At the point of interest, the device is expanded to a second diameter and perfusion flow to the vessel lumen is provided. Following the performance of a surgical procedure, perfusion flow is terminated and the device is removed from the vessel.

    摘要翻译: 公开了一种用于闭塞身体通道并随后用动脉血回流,心麻痹等流体灌注身体通道的装置。 本发明的装置是一种可扩张套管,其包括具有第一直径和第二直径的柔性可扩张管状细长体,其中,所述可扩张插管插入具有第一直径,然后膨胀至第二直径,以向 通过设置在可扩张管状细长体的远端上的至少一个动脉返回孔,其与设置在套管内的灌注腔流体连通。 该装置还可以设置有一个或多个另外的腔,用于向血管内腔提供附加功能,并且还可以包括固定在套管远端的可扩张闭塞构件,用于将手术区域与动脉系统的其余部分隔离。 还公开了本发明的优选使用方法,其中将第一直径血管内插入患者的血管并进入感兴趣点。 在感兴趣的地方,将装置扩张到第二直径,并且提供到血管腔的灌注流。 在执行外科手术之后,终止灌注流程,并且从血管中移除装置。

    Methods and apparatus for occluding a blood vessel
    95.
    发明授权
    Methods and apparatus for occluding a blood vessel 失效
    用于封闭血管的方法和装置

    公开(公告)号:US6042563A

    公开(公告)日:2000-03-28

    申请号:US49463

    申请日:1998-03-27

    摘要: An improved method and apparatus for occluding a blood vessel is shown and described. A cannula adapted for insertion through a wall of a blood vessel is provided with an expandable member on a distal end which when expanded, substantially fills a cross-sectional annular area of the lumen of the blood vessel. An external clamp is coupled to the cannula and aligned with the expandable member, such that when the clamp is engaged, it moves the annular region of the blood vessel into contact with the inflatable member, the inflatable member and clamp thereby working in cooperation to occlude the blood vessel. The cannula may further be provided with a plurality of lumens extending through the cannula to corresponding openings in a distal end of the cannula, thereby allowing the perfusion of different fluids into the lumen of the blood vessel, both upstream and downstream of the internal occluding member, as well as the venting of fluid from the lumen of the blood vessel. A suture tourniquet may also be coupled to the cannula. Multiple functions are therefore performed by a compact, efficient device that is simple to use. In addition, occlusion is achieved with minimal deformation to the blood vessel, reducing the risk of trauma to the blood vessel and the creation of emboli. The intraluminal occlusion device is also securely held in a selected position, thereby reducing risk of harm to the patient from emboli and undesirable blocking of perfusion of blood to the rest of the patient's body.

    摘要翻译: 显示和描述了用于闭塞血管的改进的方法和装置。 适于插入穿过血管壁的插管在远端设置有可扩张构件,当扩张时,基本上填充血管内腔的横截面的环形区域。 外部夹具联接到套管并与可膨胀构件对准,使得当夹具接合时,其将血管的环形区域移动与可充气构件,可充气构件和夹具接触,从而协同工作以阻塞 血管。 套管还可以设置有多个管腔,其穿过套管延伸到插管的远端中的对应开口处,从而允许不同流体在内部阻塞构件的上游和下游灌注到血管的内腔中 ,以及从血管内腔排出液体。 缝线止血带也可以联接到插管。 因此,多功能由简单易用的紧凑,高效的设备执行。 此外,通过对血管的最小变形来实现闭塞,减少对血管的创伤和产生栓塞的风险。 管腔内闭塞装置也被牢固地保持在选定的位置,从而降低了患者从栓子的危害的危险,并且不期望地阻止血液灌注到患者身体的其余部分。

    Method and apparatus for using vagus nerve stimulation in surgery
    96.
    发明授权
    Method and apparatus for using vagus nerve stimulation in surgery 失效
    手术中使用迷走神经刺激的方法和装置

    公开(公告)号:US5913876A

    公开(公告)日:1999-06-22

    申请号:US935126

    申请日:1997-09-22

    摘要: A method and apparatus for facilitating coronary surgery on the beating heart wherein the vagus nerve is electrically stimulated to purposely temporarily stop or substantially reduce the beating of the heart under precisely controlled conditions. The apparatus controllably applies the electrical stimulus to preselected locations along the vagus nerve and thus to preselected nerve branches related to the heart. The apparatus includes several clip and probe configurations for establishing electrical contact with the vagus nerve. Such purposely caused temporary stoppage or substantial reduction of the beating of the heart facilitates procedures such as suturing of an anastomosis which would otherwise be more difficult because of the motion induced by the beating heart.

    摘要翻译: 一种用于促进搏动心脏的冠状动脉手术的方法和装置,其中电刺激迷走神经以故意暂时地停止或基本上减少在精确控制的条件下的心跳。 该装置可控制地将电刺激应用于沿着迷走神经的预选位置,并因此应用于与心脏相关的预选神经分支。 该装置包括用于建立与迷走神经的电接触的多个夹子和探针配置。 这样有意地引起临时停止或大幅度减少心脏搏动的方法有助于诸如缝合吻合术的过程,否则由于跳动心脏引起的运动将更加困难。