公开(公告)号：US11000459B2

公开(公告)日：2021-05-11

申请号：US16216345

申请日：2018-12-11

Applicant: Colgate-Palmolive Company

Inventor： Madhuleena Bhadra ,  Michael Prencipe ,  Aarti Rege

IPC: A61K8/21 ,  A61K8/25 ,  A61K8/27 ,  A61K8/365 ,  A61Q11/00 ,  C09K3/14

Abstract: This invention relates to dentifrice compositions comprising stannous fluoride and a silica abrasive having a N2 BET surface area of less than 50 m2/g and an Einlehner hardness of from 4 to 11, as well as to methods of using these compositions.

公开(公告)号：US10799724B2

公开(公告)日：2020-10-13

申请号：US15768918

申请日：2015-10-22

Applicant: Colgate-Palmolive Company

Inventor： Rabab Ahmed ,  Michael Prencipe

IPC: A61K8/81 ,  A61Q11/00 ,  A61K31/167 ,  A61K31/245

Abstract: An oral care composition comprising a local anaesthetic agent, a film-forming polymer and a non-aqueous vehicle wherein the film-forming polymer comprises an alkyl vinyl ether-maleic acid or anhydride copolymer or salt thereof is provided.

公开(公告)号：US10773105B2

公开(公告)日：2020-09-15

申请号：US16425312

申请日：2019-05-29

Applicant: Colgate-Palmolive Company

Inventor： Ying Yang ,  Dandan Chen ,  Robert D'Ambrogio ,  Paul Thomson ,  Harsh Mahendra Trivedi ,  Michael Prencipe ,  James Masters ,  Stanislav Jaracz

IPC: A61Q11/00 ,  A61K8/34 ,  A61K8/35 ,  A61K8/365 ,  A61Q17/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/27 ,  A61K8/97 ,  A61K36/9068 ,  A61K45/06

Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

公开(公告)号：US10576032B2

公开(公告)日：2020-03-03

申请号：US15104780

申请日：2014-12-10

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang

IPC: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/365

Abstract: An oral care composition comprising serine and one or more zinc salts for use in reducing or inhibiting biofilm formation in an oral cavity.

公开(公告)号：US10555883B2

公开(公告)日：2020-02-11

申请号：US15548857

申请日：2016-06-24

Applicant: Colgate-Palmolive Company

Inventor： Paul Thomson ,  Nihal Dogu ,  Michael Prencipe ,  Amy Russo ,  Hans Stettler ,  Andre Michelle Morgan

IPC: A61K8/44 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/27 ,  A61K8/34 ,  A61K8/362 ,  A61K8/25 ,  A61K8/365

Abstract: This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.

公开(公告)号：US10537504B2

公开(公告)日：2020-01-21

申请号：US15674781

申请日：2017-08-11

Applicant: Colgate-Palmolive Company

Inventor： Aarti Rege ,  Michael Prencipe

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/44 ,  A61K8/24 ,  A61K8/365

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

公开(公告)号：US10441516B2

公开(公告)日：2019-10-15

申请号：US15068418

申请日：2016-03-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Venda Porter ,  Andre Morgan ,  Michael Prencipe ,  Sarita Mello

IPC: A61K8/27 ,  A61K8/86 ,  A61Q11/00 ,  A61K8/11 ,  A61K8/25 ,  A61K8/73 ,  A61K8/21 ,  A61K8/02

Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

公开(公告)号：US10342750B2

公开(公告)日：2019-07-09

申请号：US15106280

申请日：2014-12-19

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang ,  Steven Fisher ,  Betty Won ,  Lyndsay Schaeffer-Korbylo

IPC: A61K8/27 ,  A61K31/32 ,  A61K8/24 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same.

公开(公告)号：US10195124B2

公开(公告)日：2019-02-05

申请号：US14654512

申请日：2012-12-24

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Xiao Yi Huang ,  Yuan Hui Xie

IPC: A61K8/27 ,  A61Q11/00 ,  A61K31/32 ,  A61K8/24 ,  A61K8/19 ,  A61K8/365 ,  A61K8/21

Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

公开(公告)号：US10149804B2

公开(公告)日：2018-12-11

申请号：US15636682

申请日：2017-06-29

Applicant: Colgate-Palmolive Company

Inventor： Lin Fei ,  Prakasarao Mandadi ,  Suman Chopra ,  Michael Prencipe

IPC: A61K8/25 ,  A61K8/22 ,  A61K8/81 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a thickening system comprising a first thickening agent and a second thickening agent, wherein the first thickening agent comprises greater than 15 wt % of the mixture of the first and second thickening agents in the thickening system.