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公开(公告)号：US12265086B2
公开(公告)日：2025-04-01
申请号：US17668456
申请日：2022-02-10
Applicant: Colgate-Palmolive Company
Inventor： Dandan Chen , Harsh Mahendra Trivedi , James Masters , Richard P. Darveau , Jeffrey S. Mclean
IPC: G01N33/68
Abstract: Methods of identifying an individual as being a slow gingivitis responder or a high gingivitis responder are disclosed. Some methods are based on IL-1β levels in the individual's GCF at the site of inflammation. Some methods are based on MIF and/or CCL-1 levels in the individual's GCF in healthy tissue distant from the site of inflammation. Some disclosed methods are based on temporal differences in IL-8, IL-6 and/or TNFα levels in the individual's GCF in healthy tissue distant from the site of inflammation during the development of plaque induced inflammation. Methods of treating an individual who has gingivitis and methods of preventing gingivitis are also provided. The treatment and prevention methods comprise determining if individual is a slow gingivitis responder or a high gingivitis responder and applying oral care compositions to the individual's oral cavity.
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公开(公告)号：US11197811B2
公开(公告)日：2021-12-14
申请号：US16798492
申请日：2020-02-24
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang Liu , Long Pan , Shaotang Yuan , Jairajh Mattai , James Masters
Abstract: Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
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公开(公告)号：US10548829B2
公开(公告)日：2020-02-04
申请号：US16266661
申请日：2019-02-04
Applicant: Colgate-Palmolive Company
Inventor： Jane Ong , James Masters , Tatiana Brinzari , Chi-Yuan Cheng , Donghui Wu , Long Pan
Abstract: Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
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公开(公告)号：US11116708B2
公开(公告)日：2021-09-14
申请号：US16758434
申请日：2017-12-19
Applicant: Colgate-Palmolive Company
Inventor： Shujiang Cheng , Zeenat Nabi , Laurence Du-Thumm , Qiang Wu , Jane Ong , Halyna Siomyk , Harsh Mahendra Trivedi , James Masters , Chi-Yuan Cheng , Donghui Wu
Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
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公开(公告)号：US10524995B2
公开(公告)日：2020-01-07
申请号：US15964193
申请日：2018-04-27
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Shaotang Yuan , Shira Pilch , James Masters , Zhiqiang Liu
Abstract: Disclosed herein are mouthwashes comprising a complex of a zinc ion source and an amino acid. Methods of making and using the compositions are also provided.
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Patent Agency Ranking
公开(公告)号：US10195125B2
公开(公告)日：2019-02-05
申请号：US15668857
申请日：2017-08-04
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Jairajh Mattai , Shaotang Yuan , James Masters
IPC: A61K8/27 , A61K8/44 , A61Q11/00 , A61Q5/02 , A61Q19/10 , A61Q17/00 , A61Q15/00 , A61Q5/12 , C07F3/06
Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号：US10773105B2
公开(公告)日：2020-09-15
申请号：US16425312
申请日：2019-05-29
Applicant: Colgate-Palmolive Company
Inventor： Ying Yang , Dandan Chen , Robert D'Ambrogio , Paul Thomson , Harsh Mahendra Trivedi , Michael Prencipe , James Masters , Stanislav Jaracz
IPC: A61Q11/00 , A61K8/34 , A61K8/35 , A61K8/365 , A61Q17/00 , A61K8/21 , A61K8/22 , A61K8/27 , A61K8/97 , A61K36/9068 , A61K45/06
Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
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公开(公告)号：US10653149B2
公开(公告)日：2020-05-19
申请号：US15788852
申请日：2017-10-20
Inventor： Carl Myers , Carlo Daep , Lynette Zaidel , James Masters , Russell Composto , Hyun-Su Lee
IPC: A61K31/785 , A61Q11/00 , C08F126/02 , A01N47/44 , C11D3/37 , A61Q17/00 , C11D3/48 , A61K8/81 , C08F8/30 , C09D5/14 , C09D139/00 , A61K8/91 , A01N25/08
Abstract: Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
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公开(公告)号：US20190231667A1
公开(公告)日：2019-08-01
申请号：US16266661
申请日：2019-02-04
Applicant: Colgate-Palmolive Company
Inventor： Jane Ong , James Masters , Tatiana Brinzari , Chi-Yuan Cheng , Donghui Wu , Long Pan
Abstract: Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
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公开(公告)号：US20170340539A1
公开(公告)日：2017-11-30
申请号：US15674557
申请日：2017-08-11
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Shaotang Yuan , Shira Pilch , James Masters , Zhiqiang Liu , Vyoma Patel
CPC classification number: A61K8/44 , A61K8/042 , A61K8/20 , A61K8/21 , A61K8/27 , A61K8/442 , A61K8/731 , A61K2800/58 , A61K2800/92 , A61Q11/00
Abstract: Disclosed herein are dentifrices comprising a zinc amino acid halide, which provide a precipitate of zinc oxide upon use with dilution with water and/or saliva. Methods of making and using the dentifrices are also provided.
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